7,750 research outputs found
About possible contribution of intrinsic charm component to inclusive spectra of charmed mesons
We calculate differential energy spectra (-distributions) of charmed
particles produced in proton-nucleus collisions, assuming the existence of
intrinsic heavy quark components in the proton wave function. For the
calculation, the recently proposed factorization scheme is used, based on the
Color Glass Condensate theory and specially suited for predictions of a
production of particles with large rapidities. It is argued that the intrinsic
charm component can, if it exists, dominate in a sum of two components,
intrinsic + extrinsic, of the inclusive spectrum of charmed particles produced
in proton-nucleus collisions at high energies, in the region of medium ,
, and can give noticeable contribution to atmospheric fluxes
of prompt muons and neutrinos.Comment: 10 pages, 4 figures. Version published in J. Phys. G
Mini-laparoscopic hysterectomy for adenocarcinoma in situ of the uterine cervix using interchangeable 5-mm end effectors: a way to cross the line of minimally invasive surgery in gynaecologic oncology
The incidence of adenocarcinoma of the uterine cervix is increasing. It poses the affected women in risk and the definitive treatment requires hysterectomy. Here we describe a case of adenocarcinoma in situ of the uterine cervix successfully managed by minilaparoscopic hysterectomy using interchangeable 5-mm end effectors.info:eu-repo/semantics/publishedVersio
Non-linear QCD dynamics and exclusive production in collisions
The exclusive processes in electron-proton () interactions are an
important tool to investigate the QCD dynamics at high energies as they are in
general driven by the gluon content of proton which is strongly subject to
parton saturation effects. In this paper we compute the cross sections for the
exclusive vector meson production as well as the deeply virtual Compton
scattering (DVCS) relying on the color dipole approach and considering the
numerical solution of the Balitsky-Kovchegov equation including running
coupling corrections. We show that the small- evolution given by this
evolution equation is able to describe the DESY-HERA data and is relevant for
the physics of the exclusive observables in future electron-proton colliders
and in photoproduction processes to be measured in coherent interactions at the
LHC.Comment: 6 pages, 4 figure
Marketing authorization procedures for advanced cancer drugs: exploring the views of patients, oncologists, healthcare decision makers and citizens in France
International audienceBackground. The past decades have seen advances in cancer treatments in terms of toxicity and side effects but progress in the treatment of advanced cancer has been modest. New drugs have emerged improving progression free survival but with little impact on overall survival, raising questions about the criteria on which to base decisions to grant marketing authorizations and about the authorization procedure itself. For decisions to be fair, transparent and accountable, it is necessary to consider the views of those with relevant expertise and experience. Methods. We conducted a Q-study to explore the views of a range of stakeholders in France, involving: 54 patients (18 months after diagnosis); 50 members of the general population; 27 oncologists; 19 healthcare decision makers; and 2 individuals from the pharmaceutical industry. Results. Three viewpoints emerged, focussing on different dimensions entitled: 1) ‘Quality of life (QoL), opportunity cost and participative democracy’; 2)‘QoL and patient-centeredness’; and 3) ‘Length of life’. Respondents from all groups were associated with each viewpoint, except for healthcare decision makers, who were only associated with the first one. Conclusion. Our results highlight plurality in the views of stakeholders, emphasize the need for transparency in decision making processes, and illustrate the importance of a re-evaluation of treatments for all 3 viewpoints. In the context of advanced cancer, our results suggest that QoL should be more prominent amongst authorization criteria, as it is a concern for 2 of the 3 viewpoints
- …