5,819 research outputs found
Analytic Torsion on Hyperbolic Manifolds and the Semiclassical Approximation for Chern-Simons Theory
The invariant integration method for Chern-Simons theory for gauge group
SU(2) and manifold \Gamma\H^3 is verified in the semiclassical approximation.
The semiclassical limit for the partition function associated with a connected
sum of hyperbolic 3-manifolds is presented. We discuss briefly L^2 - analytical
and topological torsions of a manifold with boundary.Comment: 12 pages, LaTeX fil
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Asymmetry in Sexual Pheromones Is Not Required for Ascomycete Mating
Highlights
Asymmetric modification of pheromones is not required for yeast mating
Two yeast strains that express complementary pheromones and receptors mate with each other
Two yeast strains that express the same mating-type allele can mate with each other
Receptors and the pheromones determine the sexual identity of budding yeast
Summary
Background
We investigated the determinants of sexual identity in the budding yeast Saccharomyces cerevisiae. The higher fungi are divided into the ascomycetes and the basidiomycetes. Most ascomycetes have two mating types: one (called α in yeasts and MAT1-1 in filamentous fungi) produces a small, unmodified, peptide pheromone, and the other (a in yeasts and MAT1-2 in filamentous fungi) produces a peptide pheromone conjugated to a C-terminal farnesyl group that makes it very hydrophobic. In the basidiomycetes, all pheromones are lipid-modified, and this difference is a distinguishing feature between the phyla. We asked whether the asymmetry in pheromone modification is required for successful mating in ascomycetes.
Results
We cloned receptor and pheromone genes from a filamentous ascomycete and a basidiomycete and expressed these in the budding yeast, Saccharomyces cerevisiae, to generate novel, alternative mating pairs. We find that two yeast cells can mate even when both cells secrete a-like or α-like peptides. Importantly, this is true regardless of whether the cells express the a- or α-mating-type loci, which control the expression of other, sex-specific genes, in addition to the pheromones and pheromone receptors.
Conclusions
We demonstrate that the asymmetric pheromone modification is not required for successful mating of ascomycete fungi and confirm that, in budding yeast, the primary determinants of mating are the specificity of the receptors and their corresponding pheromones.Molecular and Cellular Biolog
Manejo do nitrogênio para o arroz Irrigado: doses e parcelamento da adubação em cobertura.
bitstream/item/30961/1/Circular-86.pd
Strong curvature singularities in quasispherical asymptotically de Sitter dust collapse
We study the occurrence, visibility, and curvature strength of singularities
in dust-containing Szekeres spacetimes (which possess no Killing vectors) with
a positive cosmological constant. We find that such singularities can be
locally naked, Tipler strong, and develop from a non-zero-measure set of
regular initial data. When examined along timelike geodesics, the singularity's
curvature strength is found to be independent of the initial data.Comment: 16 pages, LaTeX, uses IOP package, 2 eps figures; accepted for
publication in Class. Quantum Gra
Radion production in exclusive processes at CERN LHC
In the Randall-Sundrum (RS) scenario the compactification radius of the extra
dimension is stabilized by the radion, which is a scalar field lighter than the
graviton Kaluza-Klein states. It implies that the detection of the radion will
be the first signature of the stabilized RS model. In this paper we study the
exclusive production of the radion in electromagnetic and diffractive hadron -
hadron collisions at the LHC. Our results demonstrate that the diffractive
production of radion is dominant and should be feasible of study at CERN LHC.Comment: 6 pages, 3 figures, 1 tabl
Phases of massive scalar field collapse
We study critical behavior in the collapse of massive spherically symmetric
scalar fields. We observe two distinct types of phase transition at the
threshold of black hole formation. Type II phase transitions occur when the
radial extent of the initial pulse is less than the Compton
wavelength () of the scalar field. The critical solution is that
found by Choptuik in the collapse of massless scalar fields. Type I phase
transitions, where the black hole formation turns on at finite mass, occur when
. The critical solutions are unstable soliton stars with
masses \alt 0.6 \mu^{-1}. Our results in combination with those obtained for
the collapse of a Yang-Mills field~{[M.~W. Choptuik, T. Chmaj, and P. Bizon,
Phys. Rev. Lett. 77, 424 (1996)]} suggest that unstable, confined solutions to
the Einstein-matter equations may be relevant to the critical point of other
matter models.Comment: 5 pages, RevTex, 4 postscript figures included using psfi
Physico-chemical spectroscopic mapping of the planetary nebula NGC 40 and the 2D_NEB, a new 2D algorithm to study ionised nebulae
In this paper we present an analysis of the physical and chemical conditions
of the planetary nebula NGC 40 through spatially-resolved spectroscopic maps.
We also introduce a new algorithm --2D_NEB-- based on the well-established IRAF
nebular package, which was developed to enable the use of the spectroscopic
maps to easily estimate the astrophysical quantities of ionised nebulae. The
2D_NEB was benchmarked, and we clearly show that it works properly, since it
compares nicely with the IRAF nebular software.
Using this software, we derive the maps of several physical parameters of NGC
40. From these maps, we conclude that Te[NII] shows only a slight temperature
variation from region to region, with its values constrained between ~8,000 K
and ~9,500 K. Electron densities, on the other hand, have a much more prominent
spatial variation, as Ne[SII] values vary from ~1,000 cm^(-3) to ~3,000
cm^(-3). Maps of the chemical abundances also show significant variations. From
the big picture of our work, we strongly suggest that analysis with spatial
resolution be mandatory for more complete study of the physical and chemical
properties of planetary nebulae.Comment: 15 pages, 10 figures, 8 tables; Accepted for publication in MNRA
First-principles study of structure and magnetism in copper(Ii)-containing hybrid perovskites
We report a first-principles study of hybrid organic–inorganic perovskites with formula [A]Cu(H2 POO)3 (A = triazolium (Trz) and guanidinium (Gua), and H2 POO− = hypophosphite), and [HIm]Cu(HCO2)3 (HIm = imidazolium cation, HCO−2 = formate). The triazolium hypophosphite and the formate have been suggested as possible ferroelectrics. We study the fully relaxed structures with different magnetic orderings and possible phonon instabilities. For the [Trz]Cu hypophosphite, the Trz cation is shown to induce large octahedral distortions due to the Jahn-Teller effect, with Cu-O long-bond ordering along two perpendicular directions, which is correlated with antiferromagnetic ordering and strongly one-dimensional. We find that the structure is dynamically stable with respect to zone-center distortions, but instabilities appear along high symmetry lines in the Brillouin zone. On the other hand, for the [HIm]Cu formate, large octahedral distortions are found, with large Cu-O bonds present in half of the octahedra, in this case along a single direction, and correspondingly, the magnetism is almost two-dimensional
Training deep neural density estimators to identify mechanistic models of neural dynamics
Mechanistic modeling in neuroscience aims to explain observed phenomena in terms of underlying causes. However, determining which model parameters agree with complex and stochastic neural data presents a significant challenge. We address this challenge with a machine learning tool which uses deep neural density estimators-- trained using model simulations-- to carry out Bayesian inference and retrieve the full space of parameters compatible with raw data or selected data features. Our method is scalable in parameters and data features, and can rapidly analyze new data after initial training. We demonstrate the power and flexibility of our approach on receptive fields, ion channels, and Hodgkin-Huxley models. We also characterize the space of circuit configurations giving rise to rhythmic activity in the crustacean stomatogastric ganglion, and use these results to derive hypotheses for underlying compensation mechanisms. Our approach will help close the gap between data-driven and theory-driven models of neural dynamics
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