Steroid estrogen determination in sediment and sewage sludge: A critique of chromatographic / mass spectrometry methods incorporating a case study in method development

Current analytical methods for determining steroids in sewage sludge and sediment are reviewed and experimental data comparing LC/MS ESI and GC/MS quantification of extracts from these matrices is presented. The effect of matrix influence on method analysis and steroid recoveries was investigated and a comparison of GC and LC determination with mass spectrometry performed. Consequently upon this, an environmental analytically robust methodology is presented and using this technique analysis of sediments determined E1 to be the main steroid (<18 ng/g), EE2 and E3 were determined at far lower concentrations with minimal detection of E

An assessment of the bioaccumulation of estrone in Daphnia magna

The bioaccumulation of estrone by Daphnia magna was determined. Direct uptake via the aqueous medium occurred within the first 16 hours. A bioconcentration factor of 228 was established over all temporal periods. Ingestion via Chlorella vulgaris gave a partitioning factor of 24 which may approximate to a biomagnification factor assuming steady state conditions. These preliminary results indicate that the partitioning to Daphnia magna via the food source, Chorella vulgaris is less significant than bioconcentration

Climate justice for the southwestern coastal region of Bangladesh

Climate change is considered a moral, ethical and social issue, which makes it dierent from other developmental issues. The foremost instance of lack of justice regarding climate change is that the worst impacted areas are the ones with the lowest contribution to greenhouse gas emissions, such as the southwestern coastal region of Bangladesh (SWCRB). Climate change is principally triggered by the presence and eventual spread of industrialization. This study employed themixedmethod, combining qualitative and quantitative methods of data collection and analysis for development of a framework for climate justice. Data and information were obtained from both primary and secondary sources. In primary sources, quantitative data were collected from climate vulnerable community households using a structured close ended questionnaire and interactive sessions such as focus group discussions, in-depth interviews, key informant interviews, workshops, and case studies. This study explored the perceptions of people in the SWCRB, currently experiencing devastating eects of climate change and sea level rise including extreme natural disasters, seasonal changes, flooding, salinization, riverbank erosion, and water logging. These climate-induced changes are causing loss of housing, livelihoods, and land to the natives, in addition to a lack of access to proper nutrition, potable water, and healthcare thus exacerbating social injustice. A capability-based approach to climate justice is introduced in this paper, which allows for residents of this region to prepare and rebuild their own communities and create adaptive mechanisms based on their specific capabilities.info:eu-repo/semantics/publishedVersio

The development of GPS navigation systems in civil aircraft

The industry of civil aviation is developing in a fast manner to occupy the increasing needs for a fast, safe and comfortable transportation. To achieve these needs, some effective programs, plans, and systems designs are required. The current reliable aircraft navigation and landing systems have relatively a low level of accuracy especially in aircraft landing stage. The best landing category could be achieved requires a runway visual range up to 50 meters and automatic landing system is not in operation yet all over the world. Aircraft navigates using Radar, Radio and Satellite navigation systems. The Federal Aviation Administration (FAA) plans to replace legacy navigation systems with satellite based navigation technology. Currently, the Global Positioning System (GPS) and its augmentations is the main satellite navigation system used all over the world for air navigation applications. The development of aircraft navigation has been performed with the enhancement of GPS augmentation systems. In this paper, aircraft navigation systems and techniques will be presented in this paper to evaluate the integrity and reliability of each system, and to make a comparison among these systems according to accuracy, integrity and availability

Exploring Gender and Climate Change Nexus, and Empowering Women in the South Western Coastal Region of Bangladesh for Adaptation and Mitigation

This study has been conducted to identify vulnerabilities and effects of climate change on women in 12 unions in Shyamnagar upazila in the Satkhira district in the Southwestern Coastal Region of Bangladesh (SWCRB). Climate vulnerability and gender inequality may increase due to climate change. Women may, thus, face specific conditions of vulnerability in society and daily livelihood. This paper focuses on investigating factors that influence women’s vulnerability from climate change, their adaptations, and the importance of women empowerment to reduce their inequality in SWCRB. This study also emphasizes gender inequality caused by climate change, and looks at accommodations for women to reduce hostile influences of climate change. From the 9 unions in SWCRB, a total of 320 household respondents were randomly selected to complete a questionnaire. The results of the statistical analysis showed that most of the survey’s perimeter has significant. Interviews, case studies, focus group discussions, workshops, and key informant interviews were also conducted from 12 unions, and it was found that climate change impacts men and women differently, with women being more vulnerable than men. Through case study this paper investigated the main factors influencing the vulnerability of women. In terms of empowerment women may also be well positioned to lead adaptation efforts alongside men, as this analysis represent that gender inequalities are leading by social norms. Women being more vulnerable both in short-term i.e., major natural disasters, cyclones, flood, and long-term i.e., sea level rise, salinity intrusion in water and soil, land erosion, droughts, climatic events, as they enhance gender inequalities. Further, gender inequality is seen in illiteracy, food shortages and poor health conditions, traditional norms, religious taboos, and patriarchy. Moreover, gender-based economic opportunities, women’s mobility, and income are changing, while household authority relations and gender-based socio-economic, cultural, and institutional constraints remain. This study examines the increased vulnerability of women in SWCRB to climate change, which can be mitigated through women empowerment; female involvement with environmentally friendly stoves, rural electrification and renewable energy development, microfinancing, and nakshikantha. (Nakshikantha is a special type of sewing art that is made by creating designs with different types of colored threads on plain stitches). Lastly, women may also lead adaptation efforts alongside men, make decisions, and promote their participation.info:eu-repo/semantics/publishedVersio

The fate of steroid estrogens: Partitioning during wastewater treatment and onto river sediments

This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2010 Springer Science+Business Media B.V.The partitioning of steroid estrogens in wastewater treatment and receiving waters is likely to influence their discharge to, and persistence in, the environment. This study investigated the partitioning behaviour of steroid estrogens in both laboratory and field studies. Partitioning onto activated sludge from laboratory-scale Husmann units was rapid with equilibrium achieved after 1 h. Sorption isotherms and Kd values decreased in the order 17α-ethinyl estradiol > 17α-estradiol > estrone > estriol without a sorption limit being achieved (1/n >1). Samples from a wastewater treatment works indicated no accumulation of steroid estrogens in solids from primary or secondary biological treatment, however, a range of steroid estrogens were identified in sediment samples from the River Thames. This would indicate that partitioning in the environment may play a role in the long-term fate of estrogens, with an indication that they will be recalcitrant in anaerobic conditions.EPSR

Intratumoral patterns of clonal evolution in gliomas

Few studies have explored the patterns of clonal evolution in gliomas. Here, we investigate the cytogenetic patterns of intratumoral clonal evolution of gliomas and their impact on tumor histopathology and patient survival. Cytogenetic analysis of 90 gliomas was performed in individual tumor cells (>200 cells/tumor) using multicolor (N = 16 probes) interphase-FISH. Overall, chromosome gains were more frequent than chromosome losses. Gains of chromosome 7 and/or EGFR amplification were detected in 91% of the cases, whereas del(9p21) (77%) and del(10q23) (78%) were the most frequent chromosome losses. Virtually, all cases (99%) showed >/=2 tumor cell clones, with higher numbers among high- versus low-grade gliomas (p = 0.001). Nine different cytogenetic patterns were found in the ancestral tumor clones. In most gliomas, ancestral clones showed abnormalities of chromosome 7, 9p, and/or 10q and cytogenetic evolution consisted of acquisition of additional abnormalities followed by tetraploidization. Conversely, early tetraploidization was associated with low-grade astrocytomas-2/3 pilocytic and 3/6 grade II diffuse astrocytomas-and combined loss of 1p36/19q13 with oligodendrogliomas, respectively; both aberrations were associated with a better patient outcome (p = 0.03). Overall, our results support the existence of different pathways of intratumoral evolution in gliomas

Imaging high-dimensional spatial entanglement with a camera

The light produced by parametric down-conversion shows strong spatial entanglement that leads to violations of EPR criteria for separability. Historically, such studies have been performed by scanning a single-element, single-photon detector across a detection plane. Here we show that modern electron-multiplying charge-coupled device cameras can measure correlations in both position and momentum across a multi-pixel field of view. This capability allows us to observe entanglement of around 2,500 spatial states and demonstrate Einstein-Podolsky-Rosen type correlations by more than two orders of magnitude. More generally, our work shows that cameras can lead to important new capabilities in quantum optics and quantum information science.Comment: 5 pages, 4 figure

A force-balanced control volume finite element method for multi-phase porous media flow modelling

A novel method for simulating multi-phase flow in porous media is presented. The approach is based on a control volume finite element mixed formulation and new force-balanced finite element pairs. The novelty of the method lies in: (a) permitting both continuous and discontinuous description of pressure and saturation between elements; (b) the use of arbitrarily high-order polynomial representation for pressure and velocity and (c) the use of high-order flux-limited methods in space and to time avoid introducing non-physical oscillations while achieving high-order accuracy where and when possible. The model is initially validated for two-phase flow. Results are in good agreement with analytically obtained solutions and experimental results. The potential of this method is demonstrated by simulating flow in a realistic geometry composed of highly permeable meandering channels

Internalized HIV/AIDS-related Stigma in a Sample of HIV-positive People in Bangladesh

Internalized stigma among people living with HIV/AIDS (PLHA) is prevalent in Bangladesh. A better understanding of the effects of stigma on PLHA is required to reduce this and to minimize its harmful effects. This study employed a quantitative approach by conducting a survey with an aim to know the prevalence of internalized stigma and to identify the factors associated with internalized stigma among a sample of 238 PLHA (male=152 and female=86) in Bangladesh. The findings suggest that there is a significant difference between groups with the low and the high-internalized HIV/AIDS stigma in terms of both age and gender. The prevalence of internalized stigma varied according to the poverty status of PLHA. An exploratory factor analysis (EFA) found 10 of 15 items loaded highly on the three factors labelled self-acceptance, self-exclusion, and social withdrawal. About 68% of the PLHA felt ashamed, and 54% felt guilty because of their HIV status. More than half (87.5% male and 19.8% female) of the PLHA blamed themselves for their HIV status while many of them (38.2% male and 8.1% female) felt that they should be punished. The male PLHA more frequently chose to withdraw themselves from family and social gatherings compared to the female PLHA. They also experienced a higher level of internalized stigma compared to the female PLHA. The results suggest that the prevalence of internalized stigma is high in Bangladesh, and much needs to be done by different organizations working for and with the PLHA to reduce internalized stigma among this vulnerable group