368 research outputs found

    Wasting Time on the Internet

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    Curatorial note from Digital Pedagogy in the Humanities: The course Wasting Time on the Internet starts with this basic premise: How do you make art out of the enormity of the Web, the Internet, and everything in between? What happens if you start with the premise that there will be no textbook, nothing you need to buy at the bookstore, nothing the library needs to license on your behalf, and you simply set students loose to do what they will, and make what they can? Wasting Time on the Internet depends upon an open Internet for the students to ramble through. As such, it is a fascinating case study, as Katy Waldman notes in “Frontiers of the Stuplime,” in not just meeting students where they are but pushing them to move beyond multitasking into a mode of pure distraction and play, all the while encouraging a level of self-awareness and reflection on what it means to create art in an age of information excess, and how the Internet shapes knowledges and identity

    Using HSV-Thymidine Kinase for Safety in an Allogeneic Salivary Graft Cell Line

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    Extreme salivary hypofunction is a result of tissue damage caused by irradiation therapy for cancer in the head and neck region. Unfortunately, there is no currently satisfactory treatment for this condition that affects up to 40,000 people in the United States every year. As a novel approach to managing this problem, we are attempting to develop an orally implantable, fluid-secreting device (an artificial salivary gland). We are using the well-studied HSG salivary cell line as a potential allogeneic graft cell for this device. One drawback of using a cell line is the potential for malignant transformation. If such an untoward response occurred, the device could be removed. However, in the event that any HSG cells escaped, we wished to provide additional patient protection. Accordingly, we have engineered HSG cells with a hybrid adeno-retroviral vector, AdLTR.CMV-tk, to express the herpes simplex virus thymidine kinase (HSV-tk) suicide gene as a novel safety factor. Cells were grown on plastic plates or on poly-L-lactic acid disks and then transduced with different multiplicities of infection (MOIs) of the hybrid vector. Thereafter, various concentrations of ganciclovir (GCV) were added, and cell viability was tested. Transduced HSG cells expressed HSV-tk and were sensitive to GCV treatment. Maximal effects were seen at a MOI of 10 with 50 ÎĽM of GCV, achieving 95% cell killing on the poly-L-lactic acid substrate. These results suggest that engineering the expression of a suicide gene in an allogeneic graft cell may provide additional safety for use in an artificial salivary gland device.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/63119/1/10763270152436463.pd

    Control and visualisation of a software defined radio system on the Xilinx RFSoC platform using the PYNQ framework

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    The availability of commercial Radio Frequency System on Chip (RFSoC) devices brings new possibilities for implementing Software Defined Radio (SDR) systems. Such systems are of increasing interest given the pace of innovation in wireless technology, and the pressure on RF spectrum resources, leading to a growing need to access the spectrum in more dynamic and innovative ways. In this paper, we present an SDR demonstration system based on the Xilinx RFSoC platform, which leverages the Python- based 'PYNQ' (Python Productivity for Zynq) software framework. In doing so, we highlight features that can be extremely useful for prototyping radio system design. Notably, our developed system features Python-based control of hardware processing blocks and Radio Frequency (RF) data converters, as well as direct visualisation of communications signals captured within the chip. The system architecture is reviewed, hardware and software components are discussed, functionality is demonstrated, and aspects of the system's performance are evaluated. Finally, it is noted that this combined RFSoC + PYNQ approach is readily extensible for other SDR systems; we highlight our online shared resources, and invite other engineers to investigate and build upon our work

    Manual / Issue 2 / Lorem Ipsum

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    Manual, a journal about art and its making. Lorem Ipsum.The second issue. In potently meaningful and deliberately meaningless ways, this issue, “Lorem ipsum,” celebrates text. The standard placeholder text used by designers and printers, lorem ipsum isn’t really Latin. Mangled over centuries of use, the passage has become meaningless and untranslatable—and yet it is highly useful in that in its incomprehensibility, it occupies space. Over the centuries and across many inventions and innovations in type and printing, lorem ipsum has acted as a space filler and form shaper in conventional printing, desktop publishing, and electronic typesetting. Join us as we read and read into calls to action, incantations, prayers, portrayals, missives, notes, proclamations, and musings. Softcover, 60 pages. Published 2014 by the RISD Museum. Manual 2 (Lorem Ipsum) contributors include James Allen, Alison W. Chang, Kenneth Goldsmith, Cyrus Highsmith, Jan Howard, Kate Irvin, Antoine Revoy, and Nancy Skolos.https://digitalcommons.risd.edu/risdmuseum_journals/1001/thumbnail.jp

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