Doctoral Students\u27 Relational Communication with their Advisors: A Dyadic Examination using Chickering\u27s Theory of Psychosocial Development

The purpose of this dissertation was to explore how psychosocial development affects doctoral students\u27 relationships with their advisor and their success in graduate school. Toward this goal, three objectives were identified. The first objective was to integrate Chickering and Reisser\u27s (1993) vectors of psychosocial development into the doctoral education context to understand how mature students maintain their relationships and address conflict with their advisor. The second objective was to investigate the extent to which doctoral students\u27 psychosocial development and communication behaviors affected satisfaction in the student-advisor relationship. The third objective was to examine the effect of psychosocial development on doctoral students\u27 attrition and indicators of academic success. Self-report surveys were completed by both doctoral students and graduate faculty advisors. The results revealed that students who were further progressed along the vectors of psychosocial development were more likely to use relational maintenance behaviors and handle their conflict with integrative strategies, whereas students who were not as psychosocially developed were more inclined to use distributive and avoidance strategies to handle conflict in the student-advisor relationship. Psychosocial development also positively affected doctoral students\u27 persistence, perceived time to degree, and their general success in graduate school (i.e., academic preparedness, quality of work, research self-efficacy, research productivity). The results also indicated that students\u27 relational maintenance behaviors and conflict strategies played an essential role in explaining the positive effects of psychosocial development on student-advisor relational and communication satisfaction. Taken together, the findings support the importance of psychosocial development in graduate school and provide valuable information that may be used to improve the quality of doctoral programs

On the number of partition weights with Kostka multiplicity one

Given a positive integer n, and partitions lambda and mu of n, let K-lambda mu denote the Kostka number, which is the number of semistandard Young tableaux of shape lambda and weight mu. Let J(lambda) denote the number of mu such that K lambda mu = 1. By applying a result of Berenshtein and Zelevinskii, we obtain a formula for J(lambda) in terms of restricted partition functions, which is recursive in the number of distinct part sizes of lambda. We use this to classify all partitions lambda such that J(lambda) = 1 and all lambda such that J(lambda) = 2. We then consider signed tableaux, where a semistandard signed tableau of shape lambda has entries from the ordered set {0 \u3c \u3c 1 \u3c (2) over bar \u3c 2 \u3c ...}, and such that i and (i) over bar contribute equally to the weight. For a weight (omega(0), mu) with mu a partition, the signed Kostka number K-lambda(omega 0, mu)(+/-) is defined as the number of semistandard signed tableaux of shape lambda and weight (omega(0), mu), and J(+/-)(lambda) is then defined to be the number of weights (omega(0), mu) such that K-lambda(omega 0,mu)(+/-) = 1. Using different methods than in the unsigned case, we find that the only nonzero value which J((lambda))(+/-) can take is 1, and we find all sequences of partitions with this property. We conclude with an application of these results on signed tableaux to the character theory of finite unitary groups

Thrombocytopenia and disseminated histoplasmosis in immunocompetent adults

Disseminated histoplasmosis among immunocompetent patients is rare, but may be associated with clinically significant refractory thrombocytopenia. Platelet counts often return to normal levels following antifungal therapy. Therefore, the most important management of this refractory thrombocytopenia is the recognition and treatment of histoplasmosis infection

Grassroots Professional Development via the New England Research Data Management Roundtables

Objectives: To meet the changing needs of our campuses, librarians responsible for research data services are often tasked with starting new endeavors with new populations without much support. This paper reports on a collaborative effort to build a community of practice of librarians tasked with addressing the research data needs of their campuses, describes how this effort was evaluated, and presents future opportunities. Methods: In March of 2015, three librarians found themselves in a situation of serendipitous professional development: one was seeking to provide a new method of mentorship, and two more were working on an event, hoping to broadcast it to a wider community. From these two disparate goals, the Research Data Management (RDM) Roundtables were created. The RDM Roundtables planning committee developed a low-cost professional development day divided into two parts: a morning session that detailed an idea or solution relevant to our practice, and an afternoon roundtable discussion on practical aspects of research data services. Evaluations from these events were coded in NVivo and we report on the common themes. Results: Participants returned sixty-one evaluations from four events. Five themes emerged from the evaluations: learning, sharing, format, networking, and empathy. Conclusion: The events provide a valuable professional development experience for attendees, and the authors hope that by providing a description of the events’ development, others will establish their own local communities of practice

Non-canonical odor coding in the mosquito

Aedes aegypti mosquitoes are a persistent human foe, transmitting arboviruses including dengue when they feed on human blood. Mosquitoes are intensely attracted to body odor and carbon dioxide, which they detect using ionotropic chemosensory receptors encoded by three large multi-gene families. Genetic mutations that disrupt the olfactory system have modest effects on human attraction, suggesting redundancy in odor cod-ing. The canonical view is that olfactory sensory neurons each express a single chemosensory receptor that defines its ligand selectivity. We discovered that Ae. aegypti uses a different organizational principle, with many neurons co-expressing multiple chemosensory receptor genes. In vivo electrophysiology demon-strates that the broad ligand-sensitivity of mosquito olfactory neurons depends on this non-canonical co-expression. The redundancy afforded by an olfactory system in which neurons co-express multiple chemosensory receptors may increase the robustness of the mosquito olfactory system and explain our long-standing inability to disrupt the detection of humans by mosquitoes

Spatio-temporal Models of Lymphangiogenesis in Wound Healing

Several studies suggest that one possible cause of impaired wound healing is failed or insufficient lymphangiogenesis, that is the formation of new lymphatic capillaries. Although many mathematical models have been developed to describe the formation of blood capillaries (angiogenesis), very few have been proposed for the regeneration of the lymphatic network. Lymphangiogenesis is a markedly different process from angiogenesis, occurring at different times and in response to different chemical stimuli. Two main hypotheses have been proposed: 1) lymphatic capillaries sprout from existing interrupted ones at the edge of the wound in analogy to the blood angiogenesis case; 2) lymphatic endothelial cells first pool in the wound region following the lymph flow and then, once sufficiently populated, start to form a network. Here we present two PDE models describing lymphangiogenesis according to these two different hypotheses. Further, we include the effect of advection due to interstitial flow and lymph flow coming from open capillaries. The variables represent different cell densities and growth factor concentrations, and where possible the parameters are estimated from biological data. The models are then solved numerically and the results are compared with the available biological literature.Comment: 29 pages, 9 Figures, 6 Tables (39 figure files in total

The UCSC cancer genomics browser: update 2011

The UCSC Cancer Genomics Browser (https://genome-cancer.ucsc.edu) comprises a suite of web-based tools to integrate, visualize and analyze cancer genomics and clinical data. The browser displays whole-genome views of genome-wide experimental measurements for multiple samples alongside their associated clinical information. Multiple data sets can be viewed simultaneously as coordinated ‘heatmap tracks’ to compare across studies or different data modalities. Users can order, filter, aggregate, classify and display data interactively based on any given feature set including clinical features, annotated biological pathways and user-contributed collections of genes. Integrated standard statistical tools provide dynamic quantitative analysis within all available data sets. The browser hosts a growing body of publicly available cancer genomics data from a variety of cancer types, including data generated from the Cancer Genome Atlas project. Multiple consortiums use the browser on confidential prepublication data enabled by private installations. Many new features have been added, including the hgMicroscope tumor image viewer, hgSignature for real-time genomic signature evaluation on any browser track, and ‘PARADIGM’ pathway tracks to display integrative pathway activities. The browser is integrated with the UCSC Genome Browser; thus inheriting and integrating the Genome Browser’s rich set of human biology and genetics data that enhances the interpretability of the cancer genomics data

Highlights From the Annual Meeting of the American Epilepsy Society 2022

With more than 6000 attendees between in-person and virtual offerings, the American Epilepsy Society Meeting 2022 in Nashville, felt as busy as in prepandemic times. An ever-growing number of physicians, scientists, and allied health professionals gathered to learn a variety of topics about epilepsy. The program was carefully tailored to meet the needs of professionals with different interests and career stages. This article summarizes the different symposia presented at the meeting. Basic science lectures addressed the primary elements of seizure generation and pathophysiology of epilepsy in different disease states. Scientists congregated to learn about anti-seizure medications, mechanisms of action, and new tools to treat epilepsy including surgery and neurostimulation. Some symposia were also dedicated to discuss epilepsy comorbidities and practical issues regarding epilepsy care. An increasing number of patient advocates discussing their stories were intertwined within scientific activities. Many smaller group sessions targeted more specific topics to encourage member participation, including Special Interest Groups, Investigator, and Skills Workshops. Special lectures included the renown Hoyer and Lombroso, an ILAE/IBE joint session, a spotlight on the impact of Dobbs v. Jackson on reproductive health in epilepsy, and a joint session with the NAEC on coding and reimbursement policies. The hot topics symposium was focused on traumatic brain injury and post-traumatic epilepsy. A balanced collaboration with the industry allowed presentations of the latest pharmaceutical and engineering advances in satellite symposia