Linking anthropogenic resources to wildlife-pathogen dynamics: a review and meta-analysis

Urbanisation and agriculture cause declines for many wildlife, but some species benefit from novelresources, especially food, provided in human-dominated habitats. Resulting shifts in wildlife ecol-ogy can alter infectious disease dynamics and create opportunities for cross-species transmission,yet predicting host–pathogen responses to resource provisioning is challenging. Factors enhancingtransmission, such as increased aggregation, could be offset by better host immunity due toimproved nutrition. Here, we conduct a review and meta-analysis to show that food provisioningresults in highly heterogeneous infection outcomes that depend on pathogen type and anthropo-genic food source. We also find empirical support for behavioural and immune mechanismsthrough which human-provided resources alter host exposure and tolerance to pathogens. Areview of recent theoretical models of resource provisioning and infection dynamics shows thatchanges in host contact rates and immunity produce strong non-linear responses in pathogen inva-sion and prevalence. By integrating results of our meta-analysis back into a theoretical frame-work, we find provisioning amplifies pathogen invasion under increased host aggregation andtolerance, but reduces transmission if provisioned food decreases dietary exposure to parasites.These results carry implications for wildlife disease management and highlight areas for futurework, such as how resource shifts might affect virulence evolution

A simple two-module problem to exemplify building-block assembly under crossover

Theoretically and empirically it is clear that a genetic algorithm with crossover will outperform a genetic algorithm without crossover in some fitness landscapes, and vice versa in other landscapes. Despite an extensive literature on the subject, and recent proofs of a principled distinction in the abilities of crossover and non-crossover algorithms for a particular theoretical landscape, building general intuitions about when and why crossover performs well when it does is a different matter. In particular, the proposal that crossover might enable the assembly of good building-blocks has been difficult to verify despite many attempts at idealized building-block landscapes. Here we show the first example of a two-module problem that shows a principled advantage for cross-over. This allows us to understand building-block assembly under crossover quite straightforwardly and build intuition about more general landscape classes favoring crossover or disfavoring it

Curved Tails in Polymerization-Based Bacterial Motility

The curved actin ``comet-tail'' of the bacterium Listeria monocytogenes is a visually striking signature of actin polymerization-based motility. Similar actin tails are associated with Shigella flexneri, spotted-fever Rickettsiae, the Vaccinia virus, and vesicles and microspheres in related in vitro systems. We show that the torque required to produce the curvature in the tail can arise from randomly placed actin filaments pushing the bacterium or particle. We find that the curvature magnitude determines the number of actively pushing filaments, independent of viscosity and of the molecular details of force generation. The variation of the curvature with time can be used to infer the dynamics of actin filaments at the bacterial surface.Comment: 8 pages, 2 figures, Latex2

Propagation of short-period gravity waves at high-latitudes during the MaCWAVE winter campaign

As part of the MaCWAVE (Mountain and Convective Waves Ascending Vertically) winter campaign an all-sky monochromatic CCD imager has been used to investigate the properties of short-period mesospheric gravity waves at high northern latitudes. Sequential measurements of several nightglow emissions were made from Esrange, Sweden, during a limited period from 27–31 January 2003. Coincident wind measurements over the altitude range (~80–100 km) using two meteor radar systems located at Esrange and Andenes have been used to perform a novel investigation of the intrinsic properties of five distinct wave events observed during this period. Additional lidar and MSIS model temperature data have been used to investigate their nature (i.e. freely propagating or ducted). Four of these extensive wave events were found to be freely propagating with potential source regions to the north of Scandinavia. No evidence was found for strong orographic forcing by short-period waves in the airglow emission layers. The fifth event was most unusual exhibiting an extensive, but much smaller and variable wavelength pattern that appeared to be embedded in the background wind field. Coincident wind measurements indicated the presence of a strong shear suggesting this event was probably due to a large-scale Kelvin-Helmholtz instability

Gravitational waveforms from a point particle orbiting a Schwarzschild black hole

We numerically solve the inhomogeneous Zerilli-Moncrief and Regge-Wheeler equations in the time domain. We obtain the gravitational waveforms produced by a point-particle of mass $\mu$ traveling around a Schwarzschild black hole of mass M on arbitrary bound and unbound orbits. Fluxes of energy and angular momentum at infinity and the event horizon are also calculated. Results for circular orbits, selected cases of eccentric orbits, and parabolic orbits are presented. The numerical results from the time-domain code indicate that, for all three types of orbital motion, black hole absorption contributes less than 1% of the total flux, so long as the orbital radius r_p(t) satisfies r_p(t)> 5M at all times.Comment: revtex4, 24 pages, 23 figures, 3 tables, submitted to PR

Low noise amplication of an optically carried microwave signal: application to atom interferometry

In this paper, we report a new scheme to amplify a microwave signal carried on a laser light at $\lambda$=852nm. The amplification is done via a semiconductor tapered amplifier and this scheme is used to drive stimulated Raman transitions in an atom interferometer. Sideband generation in the amplifier, due to self-phase and amplitude modulation, is investigated and characterized. We also demonstrate that the amplifier does not induce any significant phase-noise on the beating signal. Finally, the degradation of the performances of the interferometer due to the amplification process is shown to be negligible

Introduction of Empirical Topology in Construction of Relationship Networks of Informative Objects

Understanding the structure of relationships between objects in a given database is one of the most important problems in the field of data mining. The structure can be defined for a set of single objects (clustering) or a set of groups of objects (network mapping). We propose a method for discovering relationships between individuals (single or groups) that is based on what we call the empirical topology, a system-theoretic measure of functional proximity. To illustrate the suitability and efficiency of the method, we apply it to an astronomical data base

Weak Lensing of the CMB: Cumulants of the Probability Distribution Function

We discuss the real-space moments of temperature anisotropies in the cosmic microwave background (CMB) due to weak gravitational lensing by intervening large-scale structure. We show that if the probability distribution function of primordial temperature anisotropies is Gaussian, then it remains unchanged after gravitational lensing. With finite resolution, however, non-zero higher-order cumulants are generated both by lensing autocorrelations and by cross-correlations between the lensing potential and secondary anisotropies in the CMB such as the Sunayev-Zel'dovich (SZ) effect. Skewness is produced by these lensing-SZ correlations, while kurtosis receives contributions from both lensing alone and lensing-SZ correlations. We show that if the projected lensing potential is Gaussian, all cumulants of higher-order than the kurtosis vanish. While recent results raise the possibility of detection of the skewness in upcoming data, the kurtosis will likely remain undetected.Comment: 11 pages, 4 figures, submitted to PR

Evaluation of Hungarian Wines for Resveratrol by Overpressured Layer Chromatography

A method, including solid phase extraction sample preparation, overpressured layer chromatographic separation and subsequent densitometric evaluation, was developed for measurement of total resveratrol (cis- and trans-isomers) content of wine. The amount of resveratrol was determined in wine samples from different winemaking regions of Hungary. The total resveratrol was high in Hungarian red wines (3.6–11 mg/L), and much lower in white ones (0.04–1.5 mg/L)

Non-Equilibrium Statistical Physics of Currents in Queuing Networks

We consider a stable open queuing network as a steady non-equilibrium system of interacting particles. The network is completely specified by its underlying graphical structure, type of interaction at each node, and the Markovian transition rates between nodes. For such systems, we ask the question ``What is the most likely way for large currents to accumulate over time in a network ?'', where time is large compared to the system correlation time scale. We identify two interesting regimes. In the first regime, in which the accumulation of currents over time exceeds the expected value by a small to moderate amount (moderate large deviation), we find that the large-deviation distribution of currents is universal (independent of the interaction details), and there is no long-time and averaged over time accumulation of particles (condensation) at any nodes. In the second regime, in which the accumulation of currents over time exceeds the expected value by a large amount (severe large deviation), we find that the large-deviation current distribution is sensitive to interaction details, and there is a long-time accumulation of particles (condensation) at some nodes. The transition between the two regimes can be described as a dynamical second order phase transition. We illustrate these ideas using the simple, yet non-trivial, example of a single node with feedback.Comment: 26 pages, 5 figure