Description and genetic analysis of H-2 associated genes controlling early embryo development

Genes associated with the H-2 complex were shown to control the timing of early development. The gene(s) responsible for the effects was named Ped for preimplantation embryo development. Using congenic mice, it was shown that slow development is associated with the H-2(\u27k) haplotype. The gene(s) shows its effect as early as the first cleavage division, but not as early as the time of ovulation. The Ped gene(s) was shown to control not only the timing of the first cleavage division but the subsequent rate of development as well. Genetic analysis of F(,1) embryos showed dominant expression of the gene(s) and no maternal effects. Analysis of F(,2) and backcross embryos showed that background genes and environment are also involved in control of the timing of early development;With the purpose of searching for the Ped gene products, monoclonal antibodies were produced against H-2 antigens. Using a cytotoxicity assay previously developed in the laboratory and monoclonal ascites fluid, it was shown that early embryos express H-2 antigens. It was observed that expression can vary among strains. This supports the theory that the Ped product(s) could be the H-2 antigens themselves;This is the first description of H-2 associated genes involved in the control of early development. A quantitative genetics interpretation of the results is also included

The small town arts organizer : a manual for South Carolinians

The Small Town Arts Organizer was commissioned by the South Carolina Arts Commission especially for people in small towns and rural areas. It is meant to be used as a guidebook by those of you who wish to help start or operate community arts projects. In the manual we've tried to give you a complete picture of all the decisions and policies an arts organization needs to make. As you read through this manual, we suggest that you make notes or underline anything that seems to relate to your own project. Then you can use The Small Town Arts Organizer section by section, as you take care of business

Description and genetic analysis of H-2 associated genes controlling early embryo development

Genes associated with the H-2 complex were shown to control the timing of early development. The gene(s) responsible for the effects was named Ped for preimplantation embryo development. Using congenic mice, it was shown that "slow" development is associated with the H-2('k) haplotype. The gene(s) shows its effect as early as the first cleavage division, but not as early as the time of ovulation. The Ped gene(s) was shown to control not only the timing of the first cleavage division but the subsequent rate of development as well. Genetic analysis of F(,1) embryos showed dominant expression of the gene(s) and no maternal effects. Analysis of F(,2) and backcross embryos showed that background genes and environment are also involved in control of the timing of early development;With the purpose of searching for the Ped gene products, monoclonal antibodies were produced against H-2 antigens. Using a cytotoxicity assay previously developed in the laboratory and monoclonal ascites fluid, it was shown that early embryos express H-2 antigens. It was observed that expression can vary among strains. This supports the theory that the Ped product(s) could be the H-2 antigens themselves;This is the first description of H-2 associated genes involved in the control of early development. A quantitative genetics interpretation of the results is also included.</p

Nine Ways of Looking at Ourselves (Looking at Cities)

This essay appears in What We See: Advancing the Observations of Jane Jacobs (New Village Press 2010), an anthology co-published by New Village Press and The Center for the Living City collecting original essays by leading thinkers to honor the late Jane Jacobs, best-known for her first book, The Death and Life of Great American Cities. This essay explores nine different ways our own habits of perception affect our view of the culture of cities and their possible futures. An interactive website has been created for What We See at: www.whatwesee.org. Reprinted in this issue of Culture and Local Governance with permission of the author and New Village Press.Cet essai est issu d‘un ouvrage intitulé What We See: Advancing the Observations of Jane Jacobs (New Village Press 2010), une anthologie co-publiée par New Village Press et par le Center for the Living City et qui rassemble des textes originaux publiés par des auteurs prestigieux réunis afin d‘honorer la mémoire de Jane Jacobs, mieux connue pour son premier ouvrage The Death and Life of Great American Cities. Cet essai explore neuf manières différentes d‘aborder les perceptions et coutumes qui affectent notre compréhension de la culture des villes et leurs futurs possibles. Un site webinteractif a été créé pour What We See at: www.whatwesee.org

Community, Culture and Globalization

New York376 p.; bibl., illus; 27 cm

Adela Goldbard, image from RISD faculty page

https://digitalcommons.risd.edu/experimentalandfoundationstudies_history_facultyandstaffportraits/1125/thumbnail.jp

Adela Goldbard and Norm Paris

https://digitalcommons.risd.edu/experimentalandfoundationstudies_history_facultyandstaffportraits/1124/thumbnail.jp

Congenital esophageal stenosis: report of a case

Congenital esophageal stenosis is a rare condition, the most common cause is the persistency of embryonic tracheobronchial remnants. A tentative diagnosis is based on a physical examination and imaging studies. Dysphagia and vomiting are the most common complaints. A definitive diagnosis is based on a histopathologic study. The treatment of choice is surgical excision. We report a case of a four–year old girl with congenital esophageal stenosis succesfully treated with surgical excision