Paraneoplastic brainstem encephalomyelitis and atypical form of chronic inflammatory demyelinating polyneuropathy in patient with testicular germinal tumor—Is this an overlap syndrome? A case report

Paraneoplastic neurologic syndromes are diagnosed when neurologic symptoms are associated with neoplasm and other causative factors are excluded. They may precede or be simultaneous to various types of neoplasms, mainly malignant. In men up to 45–50 years old the most common cancer causing the paraneoplastic syndrome is testicle tumor, manifesting usually as limbic/brain stem encephalitis and myelitis. Usually effective treatment of underlying neoplasm brings resolution of neurologic symptoms. But corticosteroids and intravenuous immunoglobulins are also used. In the presented case a 37-year-old man was primarily diagnosed and treated for progressive tetraparesis with signs of both upper and lower motor neuron dysfunction, associated with bulbar symptoms. Having various diagnostic procedures performed an atypical form of chronic inflammatory demyelinating polyradiculoneuronopathy was primarily suspected, but eventually a discovery of endodermal sinus tumor in the testicle enabled to state the diagnosis of possible paraneoplastic syndrome. In spite of chemotherapy the patient died shortly after the diagnosis because of infectious complications. Histopathology displayed intense inflammatory changes in the brain stem as well as in cranial nerves and cervical spinal cord. The same immunological process evoked by various pathogenetic factors (infection vs. neoplasm) may cause similar clinical picture and hinder the diagnosis. Most importantly it may delay the proper way of treatment

The Nose

“The Nose” is a satirical short story of an official in St. Petersburg Russia whose nose leaves his face. This edition of “The Nose” was translated by Claud Field and originally published in 1916

Modern approaches to formation of marketing strategies in agricultural enterprises

The article considers the scientific basis for forming the directions marketing services and proposes the creation of agricultural and marketing center in the Department of Agricultural Development Kamenets-Podolsky district administrations that have developed actionable strategies of agricultural enterprises Khmelnitsky region and ensure effectiveness of their activities in the future. Suggestions in effective enterprise development based on modern research are offered – justified strategies for a matter of choice of strategy is determined by different factors that might affect in the future

The Nose

“The Nose” is a satirical short story of an official in St. Petersburg Russia whose nose leaves his face. This edition of “The Nose” was translated by Claud Field and originally published in 1916

Effect of goserelin and leuprolide added to the semen on reproductive performance in rabbits — Short communication

The aim of this study was to evaluate the ability of two synthetic GnRH analogues, goserelin and leuprolide, to induce ovulation in rabbit does using intravaginal administration. A total of 252 primiparous lactating does were randomly divided into five groups that, at the time of insemination, received the following treatments for ovulation induction: 1 µg of buserelin administered intramuscularly (control group), 5 µg of goserelin added to the semen dose (Group G5), 10 µg of goserelin added to the semen dose (Group G10), 5 µg of leuprolide added to the semen dose (Group L5), and 10 µg of leuprolide added to the semen dose (Group L10). The kindling rate was 80.5% in Group G10 and 75.0% in Group L10; these values are comparable to the kindling rate obtained in the control group (85.9%). The kindling rates in Groups G5 and L5 were significantly lower than in the control group (60.0%, 54.2% and 85.9%, respectively). The number of live-born rabbits was not significantly affected by the ovulation induction treatment. As regards the total number of rabbits born the only significant difference was observed between Groups G5 and L5. This study shows the possibility of inducing ovulation in rabbits by adding goserelin and leuprolide directly to the semen dose

The Nose

Collegiate Assessor Kovalyov awakens to discover that his nose is missing, leaving a smooth, flat patch of skin in its place. He finds and confronts his nose in the Kazan Cathedral, but from its clothing it is apparent that the nose has acquired a higher rank in the civil service than he and refuses to return to his face. Translated by Claud Field

The Nose

“The Nose” is a satirical short story of an official in St. Petersburg Russia whose nose leaves his face. This edition of “The Nose” was translated by Claud Field and originally published in 1916

Accounting and reporting in small businesses: managerial aspect Учет и отчетность на предприятиях малого бизнеса: управленческий аспект

The article states that development of small businesses envisages formation and use of a wide spectrum of economic information for providing managerial structure with timely and quality information, which requires creation of a system of managerial accounting and reporting, which should not contradict to the principle of expenses – benefits relation, when expenses on introduction of such a system would exceed the effect obtained from its functioning. It adds that the main requirements of building the system of managerial accounting in a small business should be simplicity, accessibility and clearness. The author studies interconnection of the system of managerial accounting in small businesses with the system of book-keeping and reporting on the basis of a simplified mechanism of accounting of economic operations. The article proceeds that formation of a limited volume of information in the system of accounting and analytical provision does not give a possibility to carry out timely and quality control and analysis of financial and economic state of activity and negatively influences planning and forecasting activity of a company in general. The article marks main components for formation of a subsystem of managerial accounting and reporting, develops methods of formation of reporting in the system of managerial accounting in a small business and also analyses units of managerial information in accordance with requirements of users and develops an organisational scheme of formation of economic information about production, realisation and financial flows in the system of accounting and analytical provision of activity of a small business (using example of an industrial enterprise).Развитие малых предприятий предполагает формирование и использование широкого спектра экономической информации для обеспечения управленческой структуры своевременной и качественной информацией, что требует создания системы управленческого учета и отчетности, которая не должна противоречить принципу соотношения «затраты – выгоды», когда затраты на внедрение такой системы будут превышать эффект, полученный от ее функционирования. Главными требованиями построения системы управленческого учета на небольшом предприятии должны стать простота, доступность и понятность. Автором была исследована взаимосвязь системы управленческого учета на малых предприятиях с системой бухгалтерского учета и отчетности на основе упрощенного механизма учета хозяйственных операций. Формирование ограниченного объема информации в системе учетно-аналитического обеспечения не дает возможности проведения своевременного и качественного контроля и анализа финансово-хозяйственного состояния деятельности и негативно влияет на планирование и прогнозирование деятельности предприятия в целом. В статье автором выделены основные составляющие для формирования подсистемы управленческого учета и отчетности, разработана методика формирования отчетности в системе управленческого учета на малом предприятии, а также проанализированы блоки управленческой информации в соответствии с потребностями пользователей и разработана организационная схема формирования экономической информации о производстве, реализации и финансовых потоках в системе учетно-аналитического обеспечения деятельности малого предприятия (на примере промышленного предприятия)

The compressive strength of fly ash concrete and its mineralogy

Includes bibliographical references.The use of fly ash as a cement extender in portland cement concrete is well established. Strict requirements are set for the fly ash on its physical properties and chemical composition to ensme its successful application as a partial replacement material for cement. An investigation was undertaken into the effectiveness and properties of a high carbon clinker ash when used as a cement extender at a 30 direct mass to mass substitution for portland cement. The clinker ash came from the Van Eck power station in Windhoek, Namibia and was milled to pass a 63micron sieve. For comparison fly ashes from the Escom power stations of Lethabo, Duvha and Matla were used. Both concrete and pure paste specimens were prepared for the evaluations