10 research outputs found

    Spiritual Formation Training in Christian Psychology Doctoral Programs: Introduction to Special Issue

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    This article introduces a special issue on spiritual formation training in Christian psychology doctoral programs. The importance of spiritual formation in the integration of psychology and Christianity is discussed, with a focus on the person of the psychotherapist. Student-faculty collaboration was valued throughout the preparation of the special issue, from the initial idea to peer reviewing and final editing. Finally, themes observed in the various articles are summarized and continued dialog is encouraged

    Effects of an Electronically Guided Prayer Intervention

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    Abstract Hope has been identified as an important factor in a variety of positive outcomes in psychotherapy, medicine, academic success, and for general levels of functioning. However, until now most studies on hope have been correlational in nature, and researchers have rarely sought to understand how hope can be facilitated. The present study considered the effect of prayer on experiences of hope in a national sample of Christian college students. An intervention group completed a guided prayer exercise once a day for 2 weeks. Pre and post-test levels of hope were assessed and compared to a control group, and a group that underwent daily relaxation exercises over the same 2-week period. The expectation was that hope would be increased in the prayer intervention group, but not in the relaxation group or the control groups. Results showed no significant time x group interaction effect when all 3 were compared, but a significant interaction effect was found when the prayer group was compared with the control group. Implications and suggestions for future research are discussed

    Spiritual Formation Training in the George Fox University Graduate Department of Clinical Psychology

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    Spiritual formation training in the George Fox University Graduate Department of Clinical Psychology is described. An evangelical Quaker institution, the ethos of George Fox University is intended to foster experiential spiritual development and reflective self-awareness. In a 2008 curriculum revision the faculty attempted to strengthen the experiential dimensions of spiritual formation training even at the risk of reducing training in more academic dimensions of theology and integration. A 2013 program evaluation solicited student and alumni perspectives on the effectiveness of the spiritual formation training they received. Results of the program evaluation suggest areas for future development

    Development of spirulina for the manufacture and oral delivery of protein therapeutics

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    The use of the edible photosynthetic cyanobacterium Arthrospira platensis (spirulina) as a biomanufacturing platform has been limited by a lack of genetic tools. Here we report genetic engineering methods for stable, high-level expression of bioactive proteins in spirulina, including large-scale, indoor cultivation and downstream processing methods. Following targeted integration of exogenous genes into the spirulina chromosome (chr), encoded protein biopharmaceuticals can represent as much as 15% of total biomass, require no purification before oral delivery and are stable without refrigeration and protected during gastric transit when encapsulated within dry spirulina. Oral delivery of a spirulina-expressed antibody targeting campylobacter—a major cause of infant mortality in the developing world—prevents disease in mice, and a phase 1 clinical trial demonstrated safety for human administration. Spirulina provides an advantageous system for the manufacture of orally delivered therapeutic proteins by combining the safety of a food-based production host with the accessible genetic manipulation and high productivity of microbial platforms

    Comparisons and Uncertainty in Fat and Adipose Tissue Estimation Techniques: The Northern Elephant Seal as a Case Study

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    <div><p>Fat mass and body condition are important metrics in bioenergetics and physiological studies. They can also link foraging success with demographic rates, making them key components of models that predict population-level outcomes of environmental change. Therefore, it is important to incorporate uncertainty in physiological indicators if results will lead to species management decisions. Maternal fat mass in elephant seals (<i>Mirounga</i> spp) can predict reproductive rate and pup survival, but no one has quantified or identified the sources of uncertainty for the two fat mass estimation techniques (labeled-water and truncated cones). The current cones method can provide estimates of proportion adipose tissue in adult females and proportion fat of juveniles in northern elephant seals (<i>M</i>. <i>angustirostris</i>) comparable to labeled-water methods, but it does not work for all cases or species. We reviewed components and assumptions of the technique via measurements of seven early-molt and seven late-molt adult females. We show that seals are elliptical on land, rather than the assumed circular shape, and skin may account for a high proportion of what is often defined as blubber. Also, blubber extends past the neck-to-pelvis region, and comparisons of new and old ultrasound instrumentation indicate previous measurements of sculp thickness may be biased low. Accounting for such differences, and incorporating new measurements of blubber density and proportion of fat in blubber, we propose a modified cones method that can isolate blubber from non-blubber adipose tissue and separate fat into skin, blubber, and core compartments. Lastly, we found that adipose tissue and fat estimates using tritiated water may be biased high during the early molt. Both the tritiated water and modified cones methods had high, but reducible, uncertainty. The improved cones method for estimating body condition allows for more accurate quantification of the various tissue masses and may also be transferrable to other species.</p></div

    Donanemab in early symptomatic Alzheimer disease : the TRAILBLAZER-ALZ 2 randomized clinical trial

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    Cardiovascular Efficacy and Safety of Bococizumab in High-Risk Patients

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