Model-based prognostics for batteries which estimates useful life and uses a probability density function

This invention develops a mathematical model to describe battery behavior during individual discharge cycles as well as over its cycle life. The basis for the form of the model has been linked to the internal processes of the battery and validated using experimental data. Effects of temperature and load current have also been incorporated into the model. Subsequently, the model has been used in a Particle Filtering framework to make predictions of remaining useful life for individual discharge cycles as well as for cycle life. The prediction performance was found to be satisfactory as measured by performance metrics customized for prognostics for a sample case. The work presented here provides initial steps towards a comprehensive health management solution for energy storage devices

Investigation of BIN1 Isoform in Immortalized Human Diploid Fibroblasts Transformed by SV40 T-Antigen

Bridging intergrator-1, BIN1, functions in membrane recycling, cytoskeleton regulation, DNA repair, and cell proliferation. As a tumor suppressor, BIN1 binds to c-MYC to inhibit S-phase gene transcription aand the N-terminus sequesters PARP, stopping DNA repair, and promoting apoptosis. Decreases in overall levels if BIN1 correlate with poor cancer prognosis. Additionally, BIN1 message can be alternatively spliced, creating isoforms lacking the myc-binding domain. This study was designed to investigate a potential role of BIN1 in viral tumorigenesis by comparing the accumulated levels and isoforms in immortalized human diploid fibroblasts and their simian virus 40 transformed counterparts. RTPCR, revealed several processed transcripts and immunoblotting detected a doublet depending upon the antibody employed. Thus far we have not detected a qualitative difference between the RNA transcripts amplified; however, preliminary data indicate that the lower BIN1 protein band may predominate in the transformed cells. Studies are ongoing to answer these questions

MAGIC observations of Mkn 421 in 2008, and related optical/X-ray/TeV MWL study

The HBL-type blazar Markarian 421 is one of the brightest TeV gamma-ray sources of the Northern sky. From December 2007 until June 2008 it was intensively observed in the VHE (E>100 GeV) band by the MAGIC gamma-ray telescope. The source showed intense and prolonged activity during the whole period. In some nights the integral flux rose up to 3.6 Crab units (E>200 GeV). Intra-night rapid flux variations were observed. We compared the optical (KVA) and X-ray (RXTE-ASM, Swift-XRT) data with the MAGIC VHE data, investigating the correlations between different energy bands.Comment: 4 pages,4figures, Contribution to the 31st ICRC, Lodz, Poland, July 200