5,395 research outputs found

    ACUTE OTITIS EXTERNA AS SEEN AT THE UNIVERSITY OF NIGERIA TEACHING HOSPITAL, ENUGU.

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    Aim: is to evaluate clinical features of AOE diagnosed in and to update the previous study from our facility.Methods: A prospective, clinical and laboratory study in a tertiary health facilityResults: A total of 3793 consecutive patients that attended the otorhinolaryngology clinics of the university of Nigeria teaching hospital Enugu during the period under study were assessed for clinical diagnosis of otitis externa. A total of 155 ears from127 patients were diagnosed clinically and confirmed by microbial studies as having acute otitis externa. There were 66 males and 61 females out of the 127 patients seen.71 ears had only bacteria isolated from the culture of their ear swab specimens, 28 fungus only and, 32 ears had both bacterial and fungal isolates while 24 ears had no isolates of microbes of the 3793 patients assessed.Conclusions: Acute otitis externa is a common disease in Enugu  with no gender biasand there were three times more cases of bacterial otitis externa than fungal otitis externa.

    Chemical composition of outdoor airborne particles at urban schools and possible implications for the air quality in classrooms

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    Vehicle emissions are a significant source of fine particles (Dp < 2.5 µm) in an urban environment. These fine particles have been shown to have detrimental health effects, with children thought to be more susceptible. Vehicle emissions are mainly carbonaceous in nature, and carbonaceous aerosols can be defined as either elemental carbon (EC) or organic carbon (OC). EC is a soot-like material emitted from primary sources while OC fraction is a complex mixture of hundreds of organic compounds from either primary or secondary sources (Cao et al., 2006). Therefore the ratio of OC/EC can aid in the identification of source. The purpose of this paper is to use the concentration of OC and EC in fine particles to determine the levels of vehicle emissions in schools. It is expected that this will improve the understanding of the potential exposure of children in a school environment to vehicle emissions

    Needs and challenges for assessing the environmental impacts of engineered nanomaterials (ENMs).

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    The potential environmental impact of nanomaterials is a critical concern and the ability to assess these potential impacts is top priority for the progress of sustainable nanotechnology. Risk assessment tools are needed to enable decision makers to rapidly assess the potential risks that may be imposed by engineered nanomaterials (ENMs), particularly when confronted by the reality of limited hazard or exposure data. In this review, we examine a range of available risk assessment frameworks considering the contexts in which different stakeholders may need to assess the potential environmental impacts of ENMs. Assessment frameworks and tools that are suitable for the different decision analysis scenarios are then identified. In addition, we identify the gaps that currently exist between the needs of decision makers, for a range of decision scenarios, and the abilities of present frameworks and tools to meet those needs

    Emergent trends in the reported incidence of prostate cancer in Nigeria

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    Godwin O Ifere1, Fisseha Abebe2, Godwin A Ananaba1,31Department of Biological Sciences, 2Department of Mathematical Sciences, 3Center for Cancer Research and Therapeutic Development, Clark Atlanta University, Atlanta, GA, USABackground: To date there has not been any nationwide age-standardized incidence data reported for prostate cancer in Nigeria. We examined and integrated diverse trends in the age-specific incidence of prostate cancer into a comprehensive trend for Nigeria, and examined how best the existing data could generate a countrywide age-standardized incidence rate for the disease.Methods: Data were obtained from studies undertaken between 1970 and 2007 in referral hospital-based cancer registries. Records from at least one tertiary hospital in each of the six geopolitical zones of Nigeria were examined retrospectively. Data were also reported for the rural population in cross-sectional prospective studies. Age-standardized incidence rates and the annual incidence of disease were calculated.Results: Higher incidence rates for prostate cancer during this period were recorded for patients aged 60&amp;ndash;69 years and 70&amp;ndash;79 years, with a lower incidence rate for patients aged younger than 50 years. An exponential annual incidence rate of disease was observed in the 50&amp;ndash;79 year age group and peaked at 70&amp;ndash;79 years before dropping again at age 80 years. The results showed metastasis in more than half of these hospital-based prostate tumors.Conclusion: Our results suggest that prostate cancer occurs at a relatively young age in Nigerians and that hospital-based registry reports may not appropriately reflect the incidence of the disease in Nigeria. A countrywide screening program is urgently needed. Finally, the difference in reported stages of disease found in Nigerians and African-Americans versus Caucasians suggests biological differences in the prognosis. Nigeria may thus typify one of the ancestral populations that harbor inherited genes predisposing African-Americans to high-risk prostate cancer.Keywords: prostate cancer, annual age-standardized incidence rate, Nigeria cancer registr

    Population mapping in informal settlements with high-resolution satellite imagery and equitable ground-truth

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    We propose a generalizable framework for the population estimation of dense, informal settlements in low-income urban areas–so called ’slums’–using high-resolution satellite imagery. Precise population estimates are a crucial factor for efficient resource allocations by government authorities and NGO’s, for instance in medical emergencies. We utilize equitable ground-truth data, which is gathered in collaboration with local communities: Through training and community mapping, the local population contributes their unique domain knowledge, while also maintaining agency over their data. This practice allows us to avoid carrying forward potential biases into the modeling pipeline, which might arise from a less rigorous ground-truthing approach. We contextualize our approach in respect to the ongoing discussion within the machine learning community, aiming to make real-world machine learning applications more inclusive, fair and accountable. Because of the resource intensive ground-truth generation process, our training data is limited. We propose a gridded population estimation model, enabling flexible and customizable spatial resolutions. We test our pipeline on three experimental site in Nigeria, utilizing pre-trained and fine-tune vision networks to overcome data sparsity. Our findings highlight the difficulties of transferring common benchmark models to real-world tasks. We discuss this and propose steps forward

    Impact of luminance and spatial parameters on the generation of the human pattern electroretinogram.

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    The current work assessed some of the key hypotheses behind the generation of the pattern electroretinogram (PERG) response. The first of these hypotheses states that the PERG response is the result of linear cancellation of simultaneous increment and decrement retinal responses, as generated by the retinal ON- and OFF-pathways. Experiment 1 evaluated the possibility of simulating the PERG by summing the ERG responses elicited by increment and decrement flashes, and found that it was indeed possible to simulate the PERG from these responses. However, only the steady-state PERG could be modeled consistently. The second hypothesis evaluated a theory that the retinal ganglion cells (RGCs) which generate the PERG response should be sensitive to spatial scaling of the PERG stimulus, and that an optimal spatial stimulus can be constructed based on the density of RGCs as a function of eccentricity. Validity of this claim was assessed by comparing the spatial tuning from uniform checkerboard stimuli to spatially-scaled gratings that mimicked the continuous change in RGC receptive field size. Spatial tuning was only found in response to uniform checkerboard stimuli. Experiment 3 tested the validity of the results from Experiment 1 in a population of glaucoma patients. Both the N95 and steady-state amplitudes from simulations could be modeled in patients and age-similar controls. While the PERG response and the simulated PERG both appear to track perimetric data, the sample size was too small to address the predictive validity of the PERG modeling as a tool for tracking disease progression

    M-1 injector development - Philosophy and implementation

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    Subscale and full scale test firings of M-1 injector to improve combustion efficienc

    An Economic analysis of the potential for precision farming in UK cereal production

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    The results from alternative spatial nitrogen application studies are analysed in economic terms and compared to the costs of precision farming hardware, software and other services for cereal crops in the UK. At current prices, the benefits of variable rate application of nitrogen exceed the returns from a uniform application by an average of £22 ha−1 The cost of the precision farming systems range from £5 to £18 ha−1 depending upon the system chosen for an area of 250 ha. The benefits outweigh the associated costs for cereal farms in excess of 80 ha for the lowest price system to 200–300 ha for the more sophisticated systems. The scale of benefits obtained depends upon the magnitude of the response to the treatment and the proportion of the field that will respond. To be cost effective, a farmed area of 250 ha of cereals, where 30% of the area will respond to variable treatment, requires an increase in crop yield in the responsive areas of between 0·25 and 1.00 t ha−1 (at £65 t−1) for the basic and most expensive precision farming systems, respectively

    Trade openness and economic growth in East African Community economies: A panel causality test

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    Abstract. In spite of financial liberalization that has been discussed and studied over the past decades, the debate for the East African Community (EAC) still remain open on the relationship between trade openness and economic growth that has a link with trade-economic policies. This paper analyzes the relationship by employing the modern methodology of Dumistrescu &amp; Hurlin (2012) Panel Causality test, The Test involved a scope of 46 years from 1970-2016. The empirical finding shows that there is a bidirectional movement (causality) as trade openness increase or relaxed lead to the growth of the economy in the East African Community. The results are supported by the endogenous growth theory that openness increases economic growth. There is a feedback relationship. The main operational implication of these empirical results is that the governments of the East African economies should dismantle barriers to trade to make sure that their intended objective is not ephemeral.Keywords. East African Community, Economic growth, Panel causality test, Trade openness.JEL. C59, F43, O24
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