Testing the EPR Locality using B-Mesons

We study the possibility of testing local realistic theory (LRT), envisioned implicitly by Einstein, Podolsky and Rosen in 1935, based on the Bell inequality for the correlations in the decay modes of entangled K or B-mesons. It is shown that such a test is possible for a restricted class of LRT, despite the passive nature of decay events and/or the non-unitary treatment of the correlations which invalidate the test for general LRT. Unfortunately, the present setup of the KEKB (Belle) experiment, where the coherence of entangled B-mesons has been confirmed recently, does not admit such a test due to the inability of determining the decay times of the entangled pairs separately. The indeterminacy also poses a problem for ensuring the locality of the test, indicating that improvement to resolve the indeterminacy is crucial for the test of LRT.Comment: 14 pages, PlainTeX, minor revisio

Tide-induced reworking of planktonic foraminifers on the outer shelf and slope off the Miyako Island, southern Ryukyus, Japan: Preliminary results

Significance of sediment reworking to a shallower environment is preliminarily discussed by occurrences and oxygen isotopes of planktonic foraminifer (Globolotalia inflata) tests collected from the sea bottom sediments on the insular shelf to slope, off the Miyako Islands, southern Ryukyus, Japan. The isotopic data and comparison with the present water temperature-depth profile indicate that vertical distribution of G. inflata with size of 300-355µm ranges from 135 to 250m (average 160m). Strong tidal currents between the East China Sea and the Pacific Ocean developed in the study area may induce the transpotation of sediment particles to a shallower environment. This is demonstrated by the occurrences of this species in sediment deposited in depth shallower than inhabiting depth. The analyzed tests were not altered by long-time contact with bottom water because they preserve surface structures and a narrow range of oxygen isotopic composition. Shortly after G. inflata died and settled on sea bottom, the tests were commonly transported to the shallower environment by the upwelling, which may result from strong tidal currents and the topographic feature of the Ryukyu Island Arc

Two cases of possible neuro-Sweet disease with meningoencephalitis as the initial manifestation

We report 2 cases that were considered to be neuro-Sweet disease. They initially manifested with meningoencephalitis and no skin lesions, and rapidly improved with corticosteroid therapy. In both cases, patients complained of meningitic symptoms such as fever and headache, and HLA-B54 and -Cw1 turned out to be positive over the clinical course. Cerebrospinal fluid analysis showed increased levels of lymphocytes and protein. In case #1, fluid-attenuated inversion recovery (FLAIR), magnetic resonance imaging (MRI) and diffusion-weighted images (DWI) showed high-intensity signals in the right dorsal medulla oblongata, bilateral dorsal midbrain, and left thalamus. In case #2, FLAIR and DWI showed high-intensity signals in the bilateral cerebellar cortex and left caudate nucleus. Symptoms and MRI images were markedly improved in both cases after corticosteroid pulse therapy. According to published diagnostic criteria, these 2 cases were considered possible neuro-Sweet disease. These cases suggest that the combination of meningoencephalitis and HLA specificity is important to consider the possibility of neuro-Sweet disease, even without skin lesions

Molecular and geographic analyses of vampire bat-transmitted cattle rabies in central Brazil

<p>Abstract</p> <p>Background</p> <p>Vampire bats are important rabies virus vectors, causing critical problems in both the livestock industry and public health sector in Latin America. In order to assess the epidemiological characteristics of vampire bat-transmitted rabies, the authors conducted phylogenetic and geographical analyses using sequence data of a large number of cattle rabies isolates collected from a wide geographical area in Brazil.</p> <p>Methods</p> <p>Partial nucleoprotein genes of rabies viruses isolated from 666 cattle and 18 vampire bats between 1987 and 2006 were sequenced and used for phylogenetic analysis. The genetic variants were plotted on topographical maps of Brazil.</p> <p>Results</p> <p>In this study, 593 samples consisting of 24 genetic variants were analyzed. Regional localization of variants was observed, with the distribution of several variants found to be delimited by mountain ranges which served as geographic boundaries. The geographical distributions of vampire-bat and cattle isolates that were classified as the identical phylogenetic group were found to overlap with high certainty. Most of the samples analyzed in this study were isolated from adjacent areas linked by rivers.</p> <p>Conclusion</p> <p>This study revealed the existence of several dozen regional variants associated with vampire bats in Brazil, with the distribution patterns of these variants found to be affected by mountain ranges and rivers. These results suggest that epidemiological characteristics of vampire bat-related rabies appear to be associated with the topographical and geographical characteristics of areas where cattle are maintained, and the factors affecting vampire bat ecology.</p

Estudo imunológico e genético de 10 isolados do vírus da raiva de morcegos do Rio de Janeiro, Sudeste do Brasil

O presente trabalho visou estudar dez isolados de vírus da raiva de morcegos hematófagos e não-hematófagos do Estado do Rio de Janeiro em suas características genéticas quanto aos genes N e G. Além disso, estudou-se a resposta de camundongos vacinados com a vacina antirrábica produzida pela replicação da amostra Pitman-Moore em cultivo celular, frente ao desafio com estes isolados virais, utilizando-se um ensaio imunológico baseado no teste de potência NIH. A vacina antirrábica utilizada na imunização dos camundongos ofereceu proteção em mais de 80% dos camundongos vacinados com a diluição 1:5 da vacina, frente à maioria dos isolados. A análise filogenética do gene da proteína N apresentou um padrão de agregação dividido em variante de morcego hematófago e variante de morcego insetívoro, com todos os isolados de morcegos frugívoros Artibeus sp. tendo sido segregados com a variante característica de morcegos Desmodus rotundus. Foram observadas diferenças filogenéticas entre as variantes do vírus da raiva de morcego hematófago isoladas na Região Noroeste do Estado do Rio de Janeiro e aquelas isoladas nas Regiões Metropolitana e Sul do Estado. A substituição do resíduo ácido aspártico por ácido glutâmico na posição 118, encontradas na caracterização genética da proteína G dos isolados 704/97BR-DR e 151/98BR-DR, permite inferir que esta posição esteja relacionada à antigenicidade viral. Não foram observadas diferenças genéticas temporais entre os isolados estudados. A vacina antirrábica utilizada ofereceu proteção satisfatória contra a maioria dos isolados estudados.In the present study we analyzed ten bats rabies viruses isolated from Rio de Janeiro State, focusing on its genetic characteristics from genes N and G, and also in the response of mice vaccinated with cell-culture rabies vaccine, produced with the Pitman-Moore strain, after viral challenge with bat rabies isolates, using an immunologic essay based on NIH vaccine potency test. The vaccine used conferred protection in more than 80% of the mice vaccinated with 1:15 vaccine dilution, after viral challenge. N gene genetic analysis divided the rabies virus isolates into haematophagous and insectivorous bat variants, with all isolates from Artibeus sp. frugivorous bats being clustered with the variant characteristic of the Desmodus rotundus vampire bat. Phylogenetic differences between isolates from Northeast Region and those from the Metropolitan and South Regions of Rio de Janeiro State were observed. The substitution of an aspartic acid to a glutamic acid found in the position 118 of G gene genetic characterization from samples 704/97BR-DR and 151/98BR-DR seems to be related to viral antigenicity. There were no time-related genetic differences between the studied samples. The vaccine employed was found with satisfactory protection against the majority of the isolates used

Screw driving sounding test; a new technology in soil investigation work particularly for soft soil

Screw Driving Sounding (SDS) test has been developed in Japan as the improved version of the Swedish Weight Sounding (SWS) test. The development of SDS is to reduce the drawbacks of the SWS with the integration of rod friction estimation. Deep boring with Standard Penetration Tests (SPT) together with soil sampling for laboratory tests have been the common procedure for determining the subsurface soil profile and geotechnical engineering properties. However, the SPT which is associated with deep boring, uses high fossil fuels, needs high skilled workers and expensive. This paper presents the SDS technology and the SDS test results in comparison with the existing SPT data from six (6) selected sites in Malaysia. Results show that there is a strong correlation between SPT and SDS data, and the soil profile is better identified using SDS than the SPT. It is predicted that SDS test has the potential to replace conventional soil investigation methods, particularly in soft soils area. It is not just fast, cheap and does not require highly skilled workers but SDS tests supports green technology and sustainability in construction. Quality results are guaranteed from the usage of Industrial Revolution 4.0 technology through automation in testing and making use of the cloud computing to manage the data