7,200 research outputs found
New doors to open...and so many!
The pursuit of science is a wonderful journey of discovery along which there are a myriad of avenues to be explored. There have always been so many objects of fascination, so many questions to ask along the way, so many possibilities to understand new principles, that making the decision about which problem to address and then having the self-discipline to explore it in depth challenge all who practice the art. How then are we, as cell biologists, to cope with the mountain of information that is accumulating as we enter the twenty-first century
Power grids vulnerability: a complex network approach
Power grids exhibit patterns of reaction to outages similar to complex
networks. Blackout sequences follow power laws, as complex systems operating
near a critical point. Here, the tolerance of electric power grids to both
accidental and malicious outages is analyzed in the framework of complex
network theory. In particular, the quantity known as efficiency is modified by
introducing a new concept of distance between nodes. As a result, a new
parameter called net-ability is proposed to evaluate the performance of power
grids. A comparison between efficiency and net-ability is provided by
estimating the vulnerability of sample networks, in terms of both the metrics.Comment: 16 pages, 3 figures. Figure 2 and table II modified. Typos corrected.
Version accepted for publication in Chao
Failure of pronuclear migration and repeated divisions of polar body nuclei associated with MTOC defects in polo eggs of Drosophila
The meiotic spindle of Drosophila oocytes is acentriolar but develops an unusual central microtubule organising centre (MTOC) at the end of meiosis I. In polo oocytes, this common central pole for the two tandem spindles of meiosis II was poorly organised and in contrast to wild-type failed to maintain its associated Pav-KLP motor protein. Furthermore, the polar body nuclei failed to arrest at metaphase, and the four products of female meiosis all underwent repeated haploid division cycles on anastral spindles. This was linked to a failure to form the astral array of microtubules with which the polar body chromosomes are normally associated. The MTOC associated with the male pronucleus was also defective in polo eggs, and the sperm aster did not grow. Migration of the female pronucleus did not take place and so a gonomeric spindle could not form. We discuss these findings in relation to the known roles of polo like kinases in regulating the behaviour of MTOCs
Failure of pronuclear migration and repeated divisions of polar body nuclei associated with MTOC defects in polo eggs of Drosophila
The meiotic spindle of Drosophila oocytes is acentriolar but develops an unusual central microtubule organising centre (MTOC) at the end of meiosis I. In polo oocytes, this common central pole for the two tandem spindles of meiosis II was poorly organised and in contrast to wild-type failed to maintain its associated Pav-KLP motor protein. Furthermore, the polar body nuclei failed to arrest at metaphase, and the four products of female meiosis all underwent repeated haploid division cycles on anastral spindles. This was linked to a failure to form the astral array of microtubules with which the polar body chromosomes are normally associated. The MTOC associated with the male pronucleus was also defective in polo eggs, and the sperm aster did not grow. Migration of the female pronucleus did not take place and so a gonomeric spindle could not form. We discuss these findings in relation to the known roles of polo like kinases in regulating the behaviour of MTOCs
In vitro measurement of nucleus pulposus swelling pressure: A new technique for studies of spinal adaptation to gravity
Swelling of the intervertebral disc nucleus pulposus is altered by posture and gravity. We have designed and tested a new osmometer for in vitro determination of nucleus pulposus swelling pressure. The functional principle of the osmometer involves compressing a sample of nucleus pulposus with nitrogen gas until saline pressure gradients across a 0.45 microns Millipore filter are eliminated. Swelling pressure of both pooled dog and pooled pig lumbar disc nucleus pulposus were measured on the new osmometer and compared to swelling pressures determined using the equilibrium dialysis technique. The osmometer measured swelling pressures comparable to those obtained by the dialysis technique. This osmometer provides a rapid, direct, and accurate measurement of swelling pressure of the nucleus pulposus
Development of a drainage variable facility for soil and crop management studies on a lakebed clay soil
Jet Investigations Using the Radial Moment
We define the radial moment, , for jets produced in hadron-hadron
collisions. It can be used as a tool for studying, as a function of the jet
transverse energy and pseudorapidity, radiation within the jet and the quality
of a perturbative description of the jet shape. We also discuss how
non-perturbative corrections to the jet transverse energy affect .Comment: 14 pages, LaTeX, 6 figure
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