Aluminum-26 in calcium-aluminum-rich inclusions and chondrules from unequilibrated ordinary chondrites

In order to investigate the distribution of ^(26)A1 in chondrites, we measured aluminum-magnesium systematics in four calcium-aluminum-rich inclusions (CAIs) and eleven aluminum-rich chondrules from unequilibrated ordinary chondrites (UOCs). All four CAIs were found to contain radiogenic ^(26)Mg (^(26)Mg^*) from the decay of ^(26)A1. The inferred initial ^(26)Al/^(27)Al ratios for these objects ((^(26)Al/^(27)Al)_0 ≅ 5 × 10^(−5)) are indistinguishable from the (^(26)Al/^(27)Al)_0 ratios found in most CAIs from carbonaceous chondrites. These observations, together with the similarities in mineralogy and oxygen isotopic compositions of the two sets of CAIs, imply that CAIs in UOCs and carbonaceous chondrites formed by similar processes from similar (or the same) isotopic reservoirs, or perhaps in a single location in the solar system. We also found ^(26)Mg^* in two of eleven aluminum-rich chondrules. The (^(26)Al/^(27)Al)_0 ratio inferred for both of these chondrules is ∼1 × 10^(−5), clearly distinct from most CAIs but consistent with the values found in chondrules from type 3.0–3.1 UOCs and for aluminum-rich chondrules from lightly metamorphosed carbonaceous chondrites (∼0.5 × 10^(−5) to ∼2 × 10^(−5)). The consistency of the (^(26)Al/^(27)Al)_0 ratios for CAIs and chondrules in primitive chondrites, independent of meteorite class, implies broad-scale nebular homogeneity with respect to ^(26)Al and indicates that the differences in initial ratios can be interpreted in terms of formation time. A timeline based on ^(26)Al indicates that chondrules began to form 1 to 2 Ma after most CAIs formed, that accretion of meteorite parent bodies was essentially complete by 4 Ma after CAIs, and that metamorphism was essentially over in type 4 chondrite parent bodies by 5 to 6 Ma after CAIs formed. Type 6 chondrites apparently did not cool until more than 7 Ma after CAIs formed. This timeline is consistent with ^(26)Al as a principal heat source for melting and metamorphism

A feasibility study of the delivery of online brief cognitive-behavioral therapy (CBT-T) for eating disorder pathology in the workplace

Objective CBT-T is a brief (10 sessions) version of cognitive behavioral therapy for non-underweight eating disorders. This report describes the protocol for a single center, single group, feasibility trial of online CBT-T in the workplace as an alternative to the health-service setting. By offering mental health services for eating disorders in the workplace, greater accessibility and increased help-seeking behaviors could be achieved. Method Treatment will be delivered online over 10 weeks and offered to employees based on self-referral rather than meeting diagnostic criteria, making treatment available to employees with sub-threshold eating disorder symptoms. Results Assessments will be conducted at baseline, mid-treatment (week 4), posttreatment (week 10) and at follow-up (1 month and 3 months posttreatment). For the primary outcome, measures will include recruitment, attrition and attendance data using pre-set benchmarks to determine high, medium or low feasibility and acceptability. Qualitative participant experiences data will be analyzed using thematic analysis. Impact on work engagement and effect sizes will be determined from secondary outcome measures; the latter enabling sample size calculations for future study. Discussion These pilot data will provide insights to recruitment, acceptability, effectiveness and viability of a future fully powered clinical trial of online CBT-T in the workplace. Public Significance Statement This study will present feasibility data from an eating disorders intervention (online CBT-T) using the workplace as an alternative to the healthcare setting to recruit and treat workers. Recruitment will be based on self-reported eating and weight concerns rather than diagnosis potentially enabling treatment to employees who have not previously sought help. The data will also provide insights to recruitment, acceptability, effectiveness, and future viability of CBT-T in the workplace

Hot topics, urgent priorities, and ensuring success for racial/ethnic minority young investigators in academic pediatrics.

BackgroundThe number of racial/ethnic minority children will exceed the number of white children in the USA by 2018. Although 38% of Americans are minorities, only 12% of pediatricians, 5% of medical-school faculty, and 3% of medical-school professors are minorities. Furthermore, only 5% of all R01 applications for National Institutes of Health grants are from African-American, Latino, and American Indian investigators. Prompted by the persistent lack of diversity in the pediatric and biomedical research workforces, the Academic Pediatric Association Research in Academic Pediatrics Initiative on Diversity (RAPID) was initiated in 2012. RAPID targets applicants who are members of an underrepresented minority group (URM), disabled, or from a socially, culturally, economically, or educationally disadvantaged background. The program, which consists of both a research project and career and leadership development activities, includes an annual career-development and leadership conference which is open to any resident, fellow, or junior faculty member from an URM, disabled, or disadvantaged background who is interested in a career in academic general pediatrics.MethodsAs part of the annual RAPID conference, a Hot Topic Session is held in which the young investigators spend several hours developing a list of hot topics on the most useful faculty and career-development issues. These hot topics are then posed in the form of six "burning questions" to the RAPID National Advisory Committee (comprised of accomplished, nationally recognized senior investigators who are seasoned mentors), the RAPID Director and Co-Director, and the keynote speaker.Results/conclusionsThe six compelling questions posed by the 10 young investigators-along with the responses of the senior conference leadership-provide a unique resource and "survival guide" for ensuring the academic success and optimal career development of young investigators in academic pediatrics from diverse backgrounds. A rich conversation ensued on the topics addressed, consisting of negotiating for protected research time, career trajectories as academic institutions move away from an emphasis on tenure-track positions, how "non-academic" products fit into career development, racism and discrimination in academic medicine and how to address them, coping with isolation as a minority faculty member, and how best to mentor the next generation of academic physicians

Weak isolation by distance and geographic diversity gradients persist in Scottish relict pine forest

Gene flow is one of the main factors shaping genetic diversity within and among tree populations, and occurs through pollen and seed dispersal. Recent findings of pollen-release asynchronies in distant populations of Scots pine (Pinus sylvestris L.) within Scotland suggest that gene dispersal among more distant populations might be less effective than previously thought. Limited gene dispersal is one of the major factors causing genetic structure for neutral markers, and pollen-release asynchrony could have driven isolation by distance (IBD) among Scottish populations. Previous studies of neutral markers found little differentiation among Scottish populations of Scots pine, however they did not consider IBD over the full Scottish range. We analysed data from 6 nuclear simple sequence repeats (SSR) and 5 chloroplast SSR loci in a total of 540 individuals of Scots pine from 18 populations across Scotland. Our aim was to assess contemporary levels and distribution of genetic variation and to test if the distribution of genetic diversity was consistent with IBD. We also analysed patterns of gene flow that could have contributed to the observed patterns of variation. Levels of genetic diversity were high, for both nuclear and chloroplast markers within populations, and there was no significant differentiation among populations. A weak signal of IBD was present. We found an increase in nuclear diversity towards the East along with greater gene flow in a West-East direction commensurate with the prevailing winds. Our findings suggest that this wind-driven gene flow is dominant over genetic drift and prevents differentiation among the Scottish populations. It may also counteract any pollen-release asynchronies among populations

Compact Hyperbolic Extra Dimensions: Branes, Kaluza-Klein Modes and Cosmology

We reconsider theories with low gravitational (or string) scale M_* where Newton's constant is generated via new large-volume spatial dimensions, while Standard Model states are localized to a 3-brane. Utilizing compact hyperbolic manifolds (CHM's) we show that the spectrum of Kaluza-Klein (KK) modes is radically altered. This allows an early universe cosmology with normal evolution up to substantial temperatures, and completely negates the constraints on M_* arising from astrophysics. Furthermore, an exponential hierarchy between the usual Planck scale and the true fundamental scale of physics can emerge with only order unity coefficients. The linear size of the internal space remains small. The proposal has striking testable signatures.Comment: 4 pages, no figure

Student Satisfaction and Performance in an Online Teacher Certification Program

The article presents a study which demonstrates the effectiveness of an online post baccalaureate teacher certification program developed by a Wisconsin university. The case method approach employing multiple methods and multiple data sources were used to investigate the degree to which pre-service teachers were prepared to teach. It was concluded that the study supports online delivery as an effective means of teacher preparation, but it was limited in the number of students followed into their first year of teaching

Physical activity outcomes in afterschool programs: A group randomized controlled trial

Afterschool programs (ASPs) across the US are working towards achieving the standard of all children accumulating 30minutes of moderate-to-vigorous physical activity (MVPA) during program time. This study describes the two-year impact of an intervention designed to assist ASPs meeting the 30min/d MVPA standard

Economics of some soil conservation practices

In applying conservation and fertility improvement plans, farmers have a choice between alternative combinations of land use, fertilizer applications and erosion control practices. Within limits, they may choose between different rotations and different fertilizer applications combined with different erosion control practices and still farm the land in accordance with the soil capabilities. While land use in accordance with soil capabilities and appropriate fertilization is basic to soil conservation, these measures need to be supplemented by supporting conservation practices such as contouring, sod waterways, mulching, drainage, flumes, etc., if soil is to be conserved and improved most efficiently. Successful conservation farming (that system which will increase total farm production, build up soil fertility, control erosion and maximize earnings) cannot be tailor-made to fit all farms but involves consideration of each individual\u27s situation. The farmer (and those working with him) must analyze his problem to determine his costs and returns for the farm as a whole under alternative combinations of crops, fertilization and supporting conservation measures to determine which system will best fit his capital position and abilities and still do the conservation job