11,994 research outputs found
Extracting high fidelity quantum computer hardware from random systems
An overview of current status and prospects of the development of quantum
computer hardware based on inorganic crystals doped with rare-earth ions is
presented. Major parts of the experimental work in this area has been done in
two places, Canberra, Australia and Lund, Sweden, and the present description
follows more closely the Lund work. Techniques will be described that include
optimal filtering of the initially inhomogeneously broadened profile down to
well separated and narrow ensembles, as well as the use of advanced
pulse-shaping in order to achieve robust arbitrary single-qubit operations with
fidelities above 90%, as characterized by quantum state tomography. It is
expected that full scalability of these systems will require the ability to
determine the state of single rare-earth ions. It has been proposed that this
can be done using special readout ions doped into the crystal and an update is
given on the work to find and characterize such ions. Finally, a few aspects on
the possibilities for remote entanglement of ions in separate
rare-earth-ion-doped crystals are considered.Comment: 19 pages, 9 figures. Written for The Proceedings of the
Nobelsymposium on qubits for future quantum computers, Gothenburg, May-0
Restorative Justice-Informed Moral Acquaintance: Resolving the Dual Role Problem in Correctional and Forensic Practice
The issue of dual roles within forensic and correctional fields has typically been conceptualized as dissonance—experienced by practitioners— when attempting to adhere to the conflicting ethical requirements associated with client well-being and community protection. In this paper, we argue that the dual role problem should be conceptualized more broadly; to incorporate the relationship between the offender and their victim. We also propose that Restorative Justice (RJ) is able to provide a preliminary ethical framework to deal with this common ethical oversight. Furthermore, we unite the RJ framework with that of Ward’s (2013) moral acquaintance model to provide a more powerful approach—RJ informed moral acquaintance—aimed at addressing the ethical challenges faced by practitioners within forensic and correctional roles
Peer mentorship and positive effects on student mentor and mentee retention and academic success
This study examined how the introduction of peer mentorship in an undergraduate health and social welfare programme at a large northern university affected student learning. Using an ethnographic case study approach, the study draws upon data collected from a small group of mentors and their mentees over a period of one academic year using interviews, reflective journals, assessment and course evaluation data.
Analysis of the data collected identified a number of key findings: peer mentorship improves assessment performance for both mentee and mentor; reduces stress and anxiety, enhances participation and engagement in the academic community, and adds value to student outcomes
Maximising transparency in a doctoral thesis: The complexities of writing about the use of QSR*NVIVO within a grounded theory study
This paper discusses the challenges of how to provide a transparent account of the use of the software programme QSR*NVIVO (QSR 2000) within a Grounded Theory framework (Glaser and Strauss 1967; Strauss and Corbin 1998). Psychology students are increasingly pursuing qualitative research projects such to the extent that the UK Economic and Social Research Council (ESRC) advise that students should have skill in the use of computer assisted qualitative data analysis software (CAQDAS) (Economic and Social Research Council 2001). Unlike quantitative studies, rigid formulae do not exist for writing-up qualitative projects for doctoral theses. Most authors, however, agree that transparency is essential when communicating the findings of qualitative research. Sparkes (2001) recommends that evaluative criteria for qualitative research should be commensurable with the aims, objectives, and epistemological assumptions of the research project. Likewise, the use of CAQDAS should vary according to the research methodology followed, and thus researchers should include a discussion of how CAQDAS was used. This paper describes how the evolving process of coding data, writing memos, categorising, and theorising were integrated into the written thesis. The structure of the written document is described including considerations about restructuring and the difficulties of writing about an iterative process within a linear document
The Glassy Wormlike Chain
We introduce a new model for the dynamics of a wormlike chain in an
environment that gives rise to a rough free energy landscape, which we baptise
the glassy wormlike chain. It is obtained from the common wormlike chain by an
exponential stretching of the relaxation spectrum of its long-wavelength
eigenmodes, controlled by a single stretching parameter. Predictions for
pertinent observables such as the dynamic structure factor and the
microrheological susceptibility exhibit the characteristics of soft glassy
rheology and compare favourably with experimental data for reconstituted
cytoskeletal networks and live cells. We speculate about the possible
microscopic origin of the stretching, implications for the nonlinear rheology,
and the potential physiological significance of our results.Comment: 12 pages, 8 figures. Minor correction
sscMap: An extensible Java application for connecting small-molecule drugs using gene-expression signatures
Background: Connectivity mapping is a process to recognize novel
pharmacological and toxicological properties in small molecules by comparing
their gene expression signatures with others in a database. A simple and robust
method for connectivity mapping with increased specificity and sensitivity was
recently developed, and its utility demonstrated using experimentally derived
gene signatures.
Results: This paper introduces sscMap (statistically significant connections'
map), a Java application designed to undertake connectivity mapping tasks using
the recently published method. The software is bundled with a default
collection of reference gene-expression profiles based on the publicly
available dataset from the Broad Institute Connectivity Map 02, which includes
data from over 7000 Affymetrix microarrays, for over 1000 small-molecule
compounds, and 6100 treatment instances in 5 human cell lines. In addition, the
application allows users to add their custom collections of reference profiles
and is applicable to a wide range of other 'omics technologies.
Conclusions: The utility of sscMap is two fold. First, it serves to make
statistically significant connections between a user-supplied gene signature
and the 6100 core reference profiles based on the Broad Institute expanded
dataset. Second, it allows users to apply the same improved method to
custom-built reference profiles which can be added to the database for future
referencing. The software can be freely downloaded from
http://purl.oclc.org/NET/sscMapComment: 3 pages, 1 table, 1 eps figur
Achieving provider engagement: providers' perceptions of implementing and delivering integrated care
The literature on integrated care is limited with respect to practical learning and experience. Although some attention has been paid to organizational processes and structures, not enough is paid to people, relationships, and the importance of these in bringing about integration. Little is known, for example, about provider engagement in the organizational change process, how to obtain and maintain it, and how it is demonstrated in the delivery of integrated care. Based on qualitative data from the evaluation of a large-scale integrated care initiative in London, United Kingdom, we explored the role of provider engagement in effective integration of services. Using thematic analysis, we identified an evolving engagement narrative with three distinct phases: enthusiasm, antipathy, and ambivalence, and argue that health care managers need to be aware of the impact of professional engagement to succeed in advancing the integrated care agenda
State-of-the-Art: the quality of case study research in innovation management
The practice of innovation management is developing fast. As new concepts emerge, exploratory studies are needed and case study research is often appropriate. To investigate the usage and quality of case study research in innovation management, all of the articles published in five top journals over 20 years (1997–2016) were reviewed. Case study research accounted for 818 of the published articles in this period (12%) and an evaluation template (termed case study evaluation template: CASET) was developed to objectively assess these articles against 10 quality criteria. It was found that the quality of case study research has often been low, although it has improved over time. Similarly, quality was found to fluctuate both within and between the different innovation journals. This indicates that the peer review process for case study research is not as robust as it should be. The assessment of individual articles using the evaluation template found significant deficiencies. Many articles: did not justify why case study research was appropriate; did not apply theoretical sampling criteria; were not transparent on how conclusions were drawn from the data; did not consider validity and reliability adequately; and did not go beyond description in their interpretation. However, the evaluation template also identified 23 “exemplary studies,” which clearly addressed nearly every criterion. Such exemplary studies provide innovation management researchers with “benchmark” reading, which can help shape their own research. This article makes four contributions to the innovation management discipline. First, the evaluation template and exemplary studies can help innovation researchers improve the quality of their case study research. Second, clear recommendations are given for how reviewers can use the template to make the peer review process more consistent and robust. Third, journal editors are encouraged to consider the implications of the findings for their particular journal. Fourth, the article should stimulate a long overdue debate on methodology in innovation management research, including the use of case study research
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