The Ends of Literacy Education: Evangelical Protestantism and the Nineteenth-Century Origins of Contemporary Writing Instruction

This dissertation examines stories of transformation integral to representations of nineteenth-century American evangelical literacy instruction: transformations of literacy students into Christians and transformations of literate Christians into critics of authority. In particular, I describe how nineteenth-century evangelical literacy education was represented as a powerful engine of change for the literacy student and the student's community in novels, letter writing manuals, and tract society literature. As I read these texts, the historical representations of evangelical literacy instruction present this instruction as a two-step process of transformation in which, first, the student is transformed and, second, the student affects transformations on the people in his/her community . In unearthing these stories of transformation I am able to construct an overlooked history in which literacy and the literary intertwine with evangelical Protestantism. This history is valuable not only for what it tells us about the past, but it also sheds light on the assumptions we make today about the transformative potential of literacy education. I demonstrate, for instance, that these narratives of transformation have present-day analogues in secular, scholarly debates about transforming composition students into activists and policy-makers. In particular, I examine the metaphors and narratives composition scholars use to characterize the means by which composition courses are thought to prepare students to engage with "public" spheres

Wearable Hearing Accessory Technology

We set out in August 2017 to develop an active noise suppressing device that would be usable both in military and civilian activities. Due to constraints in knowledge and time, we decided our best course of action was to divide the project into two equal projects with the hope to be able to combine them into a single project at the end of the allotted time. This consisted of an active noise suppression device and a passive noise suppression device. The passive device would have no electronic components and the active device would be pure circuitry with no housing. This approach meant that if one of the two devices were to fail we would still have a working deliverable. Over the course of the project, the team faced many setbacks that needed to be overcome. Due to constraints with time we were unable to test as many components as we had wanted to. In future works we would want to work better with integrating the two prototypes together and testing to see if our specifications were met. We were able to however stay well below our budget when ordering our components. If we were given more time we are confident that we would be able to complete the project and make a production ready device

Trauma informed participatory research: Reflections on co-producing a research proposal

This article discusses the development of a co-produced research proposal. The authors reflect on the process of this work and some of the challenges that were experienced by a team who had a mix of lived, clinical and academic experience of the research topic. We highlight the need to embed trauma informed principles into co-produced research and the ways in which doing so can support the development of co-produced work. As such, the article focuses on how we established safety, choice, collaboration, trustworthiness and empowerment during the process of developing the proposal. Within this we offer our reflection on some of the challenges we experienced and our learning from undertaking this work

Stress-induced rearrangements of cellular networks: consequences for protection and drug design

The complexity of the cells can be described and understood by a number of networks such as protein-protein interaction, cytoskeletal, organelle, signalling, gene transcription and metabolic networks. All these networks are highly dynamic producing continuous rearrangements in their links, hubs, network-skeleton and modules. Here we describe the adaptation of cellular networks after various forms of stress causing perturbations, congestions and network damage. Chronic stress decreases link-density, decouples or even quarantines modules, and induces an increased competition between network hubs and bridges. Extremely long or strong stress may induce a topological phase transition in the respective cellular networks, which switches the cell to a completely different mode of cellular function. We summarize our initial knowledge on network restoration after stress including the role of molecular chaperones in this process. Finally, we discuss the implications of stress-induced network rearrangements in diseases and ageing, and propose therapeutic approaches both to increase the robustness and help the repair of cellular networks.Comment: 9 pages, 1 table, 2 figures, invited paper of FEBS Letters Cellular Stress special issu

Low-Level Laser Therapy Activates NF-kB via Generation of Reactive Oxygen Species in Mouse Embryonic Fibroblasts

Background Despite over forty years of investigation on low-level light therapy (LLLT), the fundamental mechanisms underlying photobiomodulation at a cellular level remain unclear. Methodology/Principal Findings In this study, we isolated murine embryonic fibroblasts (MEF) from transgenic NF-kB luciferase reporter mice and studied their response to 810 nm laser radiation. Significant activation of NF-kB was observed at fluences higher than 0.003 J/cm2 and was confirmed by Western blot analysis. NF-kB was activated earlier (1 hour) by LLLT compared to conventional lipopolysaccharide treatment. We also observed that LLLT induced intracellular reactive oxygen species (ROS) production similar to mitochondrial inhibitors, such as antimycin A, rotenone and paraquat. Furthermore, we observed similar NF-kB activation with these mitochondrial inhibitors. These results, together with inhibition of laser induced NF-kB activation by antioxidants, suggests that ROS play an important role in the laser induced NF-kB signaling pathways. However, LLLT, unlike mitochondrial inhibitors, induced increased cellular ATP levels, which indicates that LLLT also upregulates mitochondrial respiration. Conclusion We conclude that LLLT not only enhances mitochondrial respiration, but also activates the redox-sensitive NFkB signaling via generation of ROS. Expression of anti-apoptosis and pro-survival genes responsive to NFkB could explain many clinical effects of LLLT.National Institutes of Health (U.S.) (grant R01AI050875)Center for Integration of Medicine and Innovative Technology (DAMD17-02-2-0006)United States. Dept. of Defense (CDMRP Program in TBI, W81XWH-09-1-0514)United States. Air Force Office of Scientific Research (FA9950-04-1-0079

Introduction to 2022 Anthós Dossier

The articles in this dossier about Nella Larsen’s 1929 novel Passing emerged from projects the students did in my Honors 399: Honors Writing for Junior Transfer course (now numbered HON 360 in the catalog). The three pieces in this dossier demonstrate a variety of approaches to engaging in analyzing the novel

The tribological behaviour of the Fe-12Cr alloys Jethete M152 and Rex 535 from room-temperature to 600degC

SIGLEAvailable from British Library Document Supply Centre- DSC:D74311/87 / BLDSC - British Library Document Supply CentreGBUnited Kingdo