Road geometry identification with mobile mapping techniques

Durante il mio dottorato mi sono occupato di Tecniche e Tecnologie innovative per la ricostruzione della geometria dei tracciati stradali esistenti, quali ad esempio Mobile Mapping, analisi immagini e dati GIS; a fronte degli elevatissimi costi oggi richiesti per l’utilizzo di veicoli strumentati già reperibili in commercio per il raggiungimento di tali scopi, il valore aggiunto del lavoro di dottorato riguarda l’uso di strumenti a basso costo che comportano un rilevante lavoro di analisi, trattamento e correzione del dato che risente in maniera decisiva della medio/bassa qualità della strumentazione in uso. L’obiettivo della ricerca è consistito nella realizzazione di un algoritmo di riconoscimento (in ambiente MATLAB) che sia in grado di restituire la geometria as-built di una strada esistente. Parte del lavoro è stata svolta nell’analisi e nell’estrazione delle curvature locali con approcci differenti (successive circonferenze locali, funzioni polinomiali di fitting locale di vario grado e con ampiezza di analisi variabile), nonché sullo studio degli angoli di deviazione locali. Usando questi parametri, nel resto del lavoro, si è prima ricercata una metodologia d’identificazione dei diversi elementi che compongono la geometria stradale, e poi si è lavorato su procedure di fitting con svariate tecniche (minimi quadrati, metodi robusti e altri algoritmi) cercando di estrarre informazioni di carattere geometrico, quali raggi di curvatura e relativi centri, lunghezza e orientamento dei rettifili, fattori di scala delle curve di transizione

The reform of the Italian legislation on childhood immunization

Upon the proposal of the Italian government, Law n. 191/2017 has been enacted, meant to considerably raise the number of mandatory vaccinations, while leaving several others merely "recommended" (non-mandatory). Such a reform has proven necessary in light of the latest epidemiologic data reflecting a steady decrease in the rates of immunization coverage in most Italian regions over the past few years, including mandatory vaccinations. Court rulings that held vaccinations may have caused autism, or even a child's death, have probably contributed to decrease in coverage. Early interventions to mandate immunization had been put in place at the regional level, yet the Italian Government and Parliament have opted for a national piece of legislation devised to make mandatory vaccinations a requirement to gain access to the preschool system or day care services. The authors elaborate on the reform's contents and shed a light on the medical, ethical and legal elements underpinning the mandate to immunize children. As a matter of fact, possible risks arising from vaccinations are rare, and largely offset by the benefits to both the children and society at large. On the heels of the reform in question, the doctor-patient relationship is still at the forefront. In fact, citizens need to understand the value and usefulness of non-mandatory, recommended vaccines as well. Therefore, it appears necessary to improve the quality of vaccination counseling practices in childcare, but such activities need to take place within the framework of a broader strategy, centered on the fostering of a culture of prevention, backed by scientific research to the fullest extent possible

Grey-box Modelling of a Household Refrigeration Unit Using Time Series Data in Application to Demand Side Management

This paper describes the application of stochastic grey-box modeling to identify electrical power consumption-to-temperature models of a domestic freezer using experimental measurements. The models are formulated using stochastic differential equations (SDEs), estimated by maximum likelihood estimation (MLE), validated through the model residuals analysis and cross-validated to detect model over-fitting. A nonlinear model based on the reversed Carnot cycle is also presented and included in the modeling performance analysis. As an application of the models, we apply model predictive control (MPC) to shift the electricity consumption of a freezer in demand response experiments, thereby addressing the model selection problem also from the application point of view and showing in an experimental context the ability of MPC to exploit the freezer as a demand side resource (DSR).Comment: Submitted to Sustainable Energy Grids and Networks (SEGAN). Accepted for publicatio

The emergent city. Interactive relational systems between public administration and citizen to foster sustainable processes of urban development

The widespread of Information and Communication Technologies and the consequently redefinition of roles in the usage and management of the city brought along new systems of relationships and interactions that produce an auto-organisation of territories or communities, showed also through temporary transformation of the environment. In effect, cities are continuously redefined by emergent properties that may, both be originated and then impact on social, political, cultural, and economical people practices. On the other hand, through the arrangement of its patterns the city shapes the social and connective relations occurring among people. So, the city can be regarded as a complex system, that in the last years has been expanded by the widespread of communication devices and sensors connected to the Internet. In this context, the design of new patterns of interactions that focuses on the new relationship opportunities, in part offered by the Information and Communication Technologies, but not limited to them, may significantly affect sustainable processes of urban development. This paper focuses on the civic aspect of the so-called smart cities, and, in details, on the relation between citizens and Public Administration. Some existing interaction patterns are illustrated in order to support the visualisation of the dynamic relationships between citizens and Public Administration, while new possible relations derived by the interaction with the urban space are supposed

Adrenal pheochromocytoma incidentally discovered in a patient with parkinsonism

To evaluate the diagnostic route of pheochromocytoma (PHEO) in a patient under dopaminergic treatment. A 70-year-old man with Parkinsonism and under treatment with levodopa and carbidopa came to our observation for evaluation of arterial hypertension and right adrenal mass discovered incidentally. To evaluate adrenal hormone levels we performed a dexamethasone suppression test, plasma aldosterone levels and 24-hr urinary metanephrine, which revealed elevated levels of catecholamines metabolities. 123-I-metaiodobenzylguanidine SPECT scintiscan revealed raised activity within the right adrenal gland concordant with the mass. The diagnosis of PHEO was posed and an elective laparoscopic adrenalectomy was performed; histopathological examination confirmed the PHEO diagnosis. Recently the coexistence of PHEO and Parkinsonism is a very rare association of diseases, with only 3 cases reported in literature. In this article, another case is reported and diagnostic procedures are discusse

Female obesity and infertility: outcomes and regulatory guidance

: Obesity has been associated with reduced fertility, although the dynamics and mechanisms which link excess weight to reduced fertility are not yet fully clarified. Obese women, especially those with central obesity, are less likely to conceive per cycle. Obese women suffer from perturbations of the hypothalamus-pituitary-ovary axis, disturbances of the menstrual cycle and are up to three times more likely to suffer from oligo/anovulation. A delicate hormonal balance regulates follicular development and the maturation of oocytes and it has been observed that obesity can alter the hormonal environment: adipocytes, in fact, are responsible for the production of a hormone called leptin (present in high quantities in obese women) which has been associated with reduced fecundity. In addition to compromising ovulation, obesity negatively affects the development and implantation of the endometrium. The expression of polycystic ovary syndrome (PCOS) is regulated, in part, by weight, so obese women with PCOS often have a more severe phenotype and higher subfertility rates. Furthermore, obesity impairs women's response to medically assisted procreation (MAP) treatments. The authors have set out to delineate a broad-ranging overview of obesity's impact on female fertility, by drawing upon sources spanning the 1994-2022 period. Assisted reproductive technology (ART) procedures are also discussed as they relate to obese patients. In addition the dynamics by which maternal obesity reportedly affects fetal, neonatal and child development have also been briefly enunciated

Sex- and Gender-Specific Drug Abuse Dynamics: The Need for Tailored Therapeutic Approaches

Sex and gender have been gaining ever greater attention due to their associated risks, dynamics, patterns and protective factors underlying substance abuse and addiction. Such differentiations and the clarification of complexities thereof take on even greater relevance in light of drug abuse scope worldwide. According to the 2022 World Drug Report released by the United Nations Office on Drugs and Crime (UNODC), in 2020 an estimated 284 million people worldwide aged 15–64 had used a drug within the last 12 months. The authors have set out to shed a light on determinants and contributing factors of drug abuse based on sex and gender and outline policy and medicolegal remarks aimed at delineating sex- and gender-based approaches towards drug abuse therapeutic interventions that are both therapeutically and ethically/legally viable and grounded in an evidence-based set of standards. Neurobiological data suggest that estrogen may facilitate drug taking by interacting with reward- and stress-related systems. In animal research, the administration of estrogen increases drug taking and facilitates the acquisition, escalation, and reinstatement of cocaine-seeking behavior. From a medicolegal perspective, it is of utmost importance to take into account the whole picture constituting each patient profile, which certainly includes gender factors and contributors, when outlining a therapeutic approach. Failure to do so could lead to negligence-based malpractice allegations, in light of the scientific findings representing best practices with which clinicians need to comply when caring for SUD patients

Introducing TrønderMaaS : investigating business models, sustainability and users' acceptance of a MaaS system in Stjørdal and Trondheim region, Norway

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