186 research outputs found

    Mastering the Devil: A Sociological Analysis of the Practice of a Catholic Exorcist

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    This study takes the documented growth in the ministry of exorcism within the Catholic Church as a significant challenge to some accounts of secularization. After clarifying how, according to Catholic doctrine, the devil can operate in people\u2019s lives, this study offers a sociological interpretation of exorcism. This interpretation is illustrated and tested by a sociological analysis of data collected, over a period of 10 years, by a well-established Catholic priest in Italy who himself was well trained and well grounded in philosophical analysis. This sociological case study offers fresh insights into the contemporary social significance of exorcism and provides challenges for future research. In the analysis of the data, it was discovered that only 5% of the initial consultations lead to a ritual of exorcism and that a rapprochement with rituals of deliverance is found for the large majority of the cases

    Measuring the Social Perception of Religious Freedom: A Sociological Perspective

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    This article discusses the construction of the measuring instrument for the study of social perception of religious freedom (SPRF). We provide an overview of existing definitions of religious freedom from a social-science perspective, which ground the empirical research of religious freedom and describe the conceptualization of SPRF. We focus on the operationalization model and introduce the operational variables for the SPRF research, also emphasizing the political, religious, and human rights contexts of independent variables. Finally, the results of exploratory factor analysis that allow to construct the balanced model of SPRF based on statistically weighted factors and scales are presented. The theoretical and statistically tested instrument is discussed as a result of this analysis

    The persistence of spiritual experience among churchgoing and non-churchgoing Italians : sociological and psychological perspectives

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    The study presented in this article draws on theories and methods developed within the psychology of religion to examine, from a fresh perspective, a problem established within the sociology of religion: the ‘oddity of the Italian situation’. The study employs the notion of openness to mystical experience as an indicator of the level of spiritual awareness among a sample of 1,155 Italians ranging in age from 14 to 80 years. The data demonstrated that, while levels of openness to mystical experience remain quite high among non-churchgoing Italians, these levels are significantly associated with sex, age, religious attendance, and personal prayer. Moreover, the differences between attenders and non-attenders are sensitive to the ways in which aspects of mystical experience are expressed. The dialogue between the psychology of religion and the sociology of religion generates fresh insight into the religious and spiritual landscape of Italy today

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    Perceptions of the functions of religion and attitude toward religious freedom : introducing the New Indices of the Functions of Religion (NIFoR)

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    This article proposes, tests, and introduces the New Indices of the Functions of Religion (NIFoR) and explores their relevance for explaining individual differences in attitude toward religious freedom. The theory being tested is that openness to the principles of religious freedom is related to perceptions of the functions of religion in society. A review of extant literature on the functions of religion identified eleven conceptually distinct functions. These functions were operationalised by thirty items. Drawing on data provided by 1035 students in Northern Italy, factor analysis reduced these thirty items to seven latent functions of religion. Regression analysis employing these seven latent functions demonstrated that a more positive attitude toward religious freedom was associated with conceptualising religion as primarily concerned with offering meaning and moral guidance

    Edge-to-Edge Technique to Minimize Ovelapping of Multiple Bioresorbable Scaffolds Plus Drug Eluting Stents in Revascularization of Long Diffuse Left Anterior Descending Coronary Artery Disease

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    Background: Implantation of Drug Eluting Stents (DES) plus bioresorbable scaffolds (BVS) in very long diffuse left anterior descending coronary artery (LAD) disease may be problematic because of multiple devices overlapping. We sought to assess the short and mid-tern outcomes of combined implantation of DES and BVS using a novel "edge-to-edge" technique in patients with diffuse LAD disease. Methods: Patients with long diffuse LAD disease were enrolled in a prospective registry from 1st August 2014 to 1st August 2015 and treated with IVUS-aided percutaneous coronary intervention using a DES plus a single or multiple BVS using a novel "edge-to-edge" technique. Clinical follow up and invasive follow up driven by clinical justification was performed. Results: Twenty-three patients (5 females, mean age 59.1 +/- 9.1 years) were enrolled. Mean length of LAD disease was 73.1 +/- 20.6 mm. Mean number of DES and BVS implanted was 1.2 +/- 0.4 and 1.7 +/- 1.3, respectively. At a mean follow-up of 11.3 +/- 3.8 months, no stent thrombosis or MACE were observed. Angiographic and IVUS follow-up at a mean of 6.6 +/- 0.7 months showed no significant angiographic restenosis and no appreciable stent gaps. Conclusions: In revascularization of long diffuse disease of the LAD, the edge-to-edge implantation technique appears to be feasible resulting in no restenosis or thrombosis on the short-term follow-up

    Protein microarray analysis of aberrant signaling pathways in Acute Myeloid Leukemia to predict the patients responsiveness to PI3K/Akt/mTOR inhibitors

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    Mapping of deregulated kinases and protein signalling networks within tumors can provide a means to stratify patients with shared biological characteristics to the most optimal treatment, and identify drug targets. In particular, the PI3K/AKT/mTOR signaling pathways are frequently activated in blast cells from patients with acute myelogenous leukemia (AML), a neoplastic disorder characterized by the accumulation of genetically altered myelogenous cells displaying deregulated intracellular signalling pathways and aggressive clinical behavior with poor prognosis. Using Reverse Phase Protein Microarrays (RPMA), we have analyzed the phosphorylated epitopes of signal pathway proteins of 81 peripheral blood and bone marrow specimens with newly diagnosed AML. Patients are diagnosed according to blast content, FAB classification and cytogenetic analysis. Samples are enriched for leukemic cells by performing Ficoll separation to yield a mononuclear fraction with >60% blast cells. The objective of the study was to predict the sensitivity of each patient to PI3K/Akt/mTor inhibitors, to avoid unnecessary and toxic ineffective treatment of non-responsive patients. To this goal, fresh blast cells were grown for 16 h untreated or treated with phase I or phase II mTor or Akt inhibitors either alone or in combination. Remarkably, by unsupervised hierarchical clustering a strong phosphorylation/activity of most of the sampled members of the PI3K/Akt/mTOR pathway was observed in 70% of samples from AML patients. This confirms that this pathway might indeed represent a pharmacological target in many patients. Moreover, treatment with the above inhibitors had no effect on the phosphorylation of other selected targets, demonstrating the specificity of the above results (more than one different inhibitor was used to avoid off-target effects). More importantly, by the use of the above drugs, we have been able to discriminate within the “high pAkt” population a PI3K/Akt/mTOR inhibitor-responsive group of patients and a PI3K/Akt/mTOR inhibitor non-responsive group. In addition, our data indicate that the Akt pathway is hyper-activated in M4, M5 patients, compared to M0, M2 patients, and that a strong activation of most upstream and downstream Akt effectors correlates with an over-expression of the c-kit receptor (CD117). We believe these data are important because they, have the potential to define a profile for the personalized administration of targeted drugs
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