Cognitive, Behavioral, and Neural Consequences of Sex Chromosome Aneuploidy

The X chromosome has played a critical role in the development of sexually selected characteristics for over 300 million years, and during that time it has accumulated a disproportionate number of genes concerned with mental functions. There are relatively specific effects of X‐linked genes on social cognition, language, emotional regulation, visuospatial, and numerical skills. Many human X‐linked genes outside the X–Y pairing pseudoautosomal regions escape X‐inactivation. Dosage differences in the expression of such genes (which constitute at least 15% of the total) are likely to play an important role in male–female neural differentiation, and in cognitive deficits and behavioral characteristics, particularly in the realm of social communication, that are associated with sex chromosome aneuploidies

German employee inventors' compensation records: A window into the returns to patented inventions

This paper uses a novel data source, namely German employee inventors' compensation records compiled in compliance with the German Employee Invention Act of 1957 to estimate the returns to patented inventions. In contrast to patent value estimates obtained from surveys and renewals, these records primarily provide a measure of the value of the use of the invention and not the value of patent protection. While indicators of patent value explain much of the variation in these patent value estimates, the values are only weakly correlated with the estimated renewal value of the patents. The distribution of patent value from these records is highly skew, with the vast majority of the returns earned by a select set of high valued patents, consistent with finding for other measures of patent value. The value estimates however are considerably lower than recent survey estimates with most of the patents having little or no realized value, suggesting that the returns appropriated through the use of an invention may represent only a fraction of the value of a patented invention.Patents Inventors Intellectual property rights

Withdrawn behavior, leisure-time exercise behavior, and screen-time sedentary behavior in a clinical sample of youth

Few studies have explored the relation between withdrawn behavior (WB) and exercise and screen time. The current study used exploratory factor analysis to examine the factor structure of leisure-time exercise behavior (LTEB) and screentime sedentary behavior (STSB) in a clinical sample of youth. Structural equation modeling was employed to investigate the relations between WB and LTEB and STSB, conditional on gender. WB was assessed using the Child Behavior Checklist, and LTEB and STSB were measured using the Vermont Health Behavior Questionnaire. LTEB and STSB emerged as two separate factors. Gender moderated the structure of STSB only. For boys and girls, WB was inversely related to LTEB but not significantly related to STSB. LTEB and STSB are best represented as distinct, uncorrelated constructs. In addition, withdrawn youth may be at risk for poor health outcomes due to lower rates of LTEB. Mental health clinicians, sports psychologists, and related providers may be uniquely qualified to enhance motivation for sports participation in withdrawn youth. © 2016 Human Kinetics, Inc