55 research outputs found

    Sedimentological and palynological constraints on the basal Triassic sequence in Central Switzerland

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    In Central Switzerland, Mesozoic sedimentation began after erosion and peneplainisation of the Hercynian relief and late Paleozoic continental deposition in SW-NE striking pull-apart basins. The first Triassic sedimentary sequence overlaying a weathered crystalline basement consists of a relatively thin (<10 m), lithologically highly variable unit with coarse-grained siliciclastic deposits at the base, grading into a mixed sandstone/shale-dolomite sequence followed by well-bedded dolomites with chert nodules. Sedimentary texture analyses and petrological investigations revealed four different sedimentary units starting at the base with a regolith unit that represents the weathered crystalline basement. It is overlain by terrestrial plain deposits, followed by mixed siliciclastic-carbonaceous sediments and a sequence of dolomites, deposited between the supralittoral and eulittoral zones of a tidal flat (Mels-Formation), and the eulittoral to sublittoral zones of a carbonate tidal flat environment (Röti-Dolomit), respectively. Palynological data from four localities in Central Switzerland indicate a heterochronous early Anisian age (Aegean - Bithynian/Pelsonian) for the supra- to eulittoral mixed siliciclastic-carbonaceous sediments. These new biostratigraphic ages suggest that the first Triassic marine transgression in Central Switzerland is time equivalent with those of the basal Wellendolomit in Northern Switzerland but slightly older than in the Germanic Basin. Consequently, Central Switzerland was located at this time at the northern shoreline of the Tethys and not on the southern limit of the Germanic Basi

    The Bank of Japan Operations in the Period of IMF Article 14 Status--Changes of Restrictions on International Capital Movements and the Transfigurations of Artificial Cheap Money Policy -

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    This article examines the role of lay persons in the thinking and working of experts in different fields at the borders of academic knowledge production. The status of lay persons has been studied in the Public Understanding of Science (PUS) research, which has shed light on the implicit assumptions of the deficit model that experts usually apply to lay persons. This deficit model has been consistently criticized for its inadequacy. The purpose of this article is not to contribute to this critique but to focus on the conceptions of the expertise of lay persons as a necessary prerequisite of science-based recommendations in the context of application. We call such conceptions `imagined lay persons' (ILP). We argue that such conceptions fulfil a functional purpose in the interaction between different fields in knowledge societies, and that such conceptions should not be checked against some alleged essential features of lay persons. Based on four different case studies of science centres, environmental science and consultations, as well as state regulations of genetically modified organisms, the authors examine the image of these imagined lay persons and what role they play in expertise

    Essentials from the 2015 European AIDS Clinical Society (EACS) guidelines for the treatment of adult HIV-positive persons

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    BACKGROUND: The European AIDS Clinical Society (EACS) guidelines are intended for all clinicians involved in the care of HIV-positive persons, and are available in print, online, and as a free App for download for iPhone and Android. GUIDELINE HIGHLIGHTS: The 2015 version of the EACS guidelines contains major revisions in all sections; antiretroviral treatment (ART), comorbidities, coinfections and opportunistic diseases. Among the key revisions is the recommendation of ART for all HIV-positive persons, irrespectively of CD4 count, based on the Strategic Timing of AntiRetroviral Treatment (START) study results. The recommendations for the preferred and the alternative ART options have also been revised, and a new section on the use of pre-exposure prophylaxis (PrEP) has been added. A number of new antiretroviral drugs/drug combinations have been added to the updated tables on drug-drug interactions, adverse drug effects, dose adjustment for renal/liver insufficiency and for ART administration in persons with swallowing difficulties. The revisions of the coinfection section reflect the major advances in anti-hepatitis C virus (HCV) treatment with direct-acting antivirals with earlier start of treatment in individuals at increased risk of liver disease progression, and a phasing out of interferon-containing treatment regimens. The section on opportunistic diseases has been restructured according to individual pathogens/diseases and a new overview table has been added on CD4 count thresholds for different primary prophylaxes. CONCLUSIONS: The diagnosis and management of HIV infection and related coinfections, opportunistic diseases and comorbidities continue to require a multidisciplinary effort for which the 2015 version of the EACS guidelines provides an easily accessable and updated overview

    Membrane-Based Scanning Force Microscopy

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    We report the development of a scanning force microscope based on an ultrasensitive silicon nitride membrane optomechanical transducer. Our development is made possible by inverting the standard microscope geometry - in our instrument, the substrate is vibrating and the scanning tip is at rest. We present topography images of samples placed on the membrane surface. Our measurements demonstrate that the membrane retains an excellent force sensitivity when loaded with samples and in the presence of a scanning tip. We discuss the prospects and limitations of our instrument as a quantum-limited force sensor and imaging tool.</p

    Work-in-Progress-Enhancing Training in Virtual Reality with Hand Tracking and a Real Tool

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    The main goal of Virtual Training Environments(VTEs) is to maximize training success, which can be achievedby increasing the degree of immersion. While prior work mainlyfocused on the visual, auditory, and navigational aspects of im-mersion, proprioceptive aspects may be particularly important.In this work-in-progress paper, we explore this potential byimplementing an industrial VTE, which can be interacted with,using VR gloves and a tracked real tool. Further, we evaluatethe VTE in a pilot study with industry apprentices, providinginitial evidence that participants experienced high presence andlow task load, while being generally satisfied with the training

    Designing Virtual Training Environments: Does Immersion increase Task Performance?

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    One of the main characteristic of virtual reality (VR) is immersion, which leads to the creation of sophisticated illusions of reality. Accordingly, VR is already used for a wide spectrum of applications like entertainment, marketing, and training. Especially in training applications, the effect of immersion on training success is still not entirely clear, since too much immersion may cause side effects such as users experiencing high mental demand whereas too little may disturb users’ well-being. To further investigate the matter, we developed two virtual training environments, wherein users train a typical industrial assembly task either in low or high immersive VR. In a controlled pilot study, we additionally introduced a third condition, the control group, which justifies the necessity of the training. Immediately after the VR Training session, each participant completed the corresponding real assembly task in which their performance was measured. Preliminary results from our pilot study show that participants trained in high immersive VR performed better, while negative side effects could not be detected
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