Multilevel Cloud Structures over Svalbard

The presented picture of the month is a superposition of spaceborne lidar observations and high-resolution temperature fields of the ECMWF Integrated Forecast System (IFS). It displays complex tropospheric and stratospheric clouds in the Arctic winter of 2015/16. Near the end of December 2015, the unusual northeastward propagation of warm and humid subtropical air masses as far north as 80N lifted the tropopause by more than 3 km in 24 h and cooled the stratosphere on a large scale. A widespread formation of thick cirrus clouds near the tropopause and of synoptic-scale polar stratospheric clouds (PSCs) occurred as the temperature dropped below the thresholds for the existence of cloud particles. Additionally, mountain waves were excited by the strong flow at the western edge of the ridge across Svalbard, leading to the formation of mesoscale ice PSCs. The most recent IFS cycle using a horizontal resolution of 8 km globally reproduces the large-scale and mesoscale flow features and leads to a remarkable agreement with the wave structure revealed by the spaceborne observations

Airborne coherent wind lidar measurements of the momentum flux profile from orographically induced gravity waves

In the course of the GW-LCYCLE II campaign, conducted in Jan/Feb 2016 from Kiruna, Sweden, coherent Doppler wind lidar (2 µm DWL) measurements were performed from the DLR Falcon aircraft to investigate gravity waves induced by flow across the Scandinavian Alps. During a mountain wave event on 28 January 2016, a novel momentum flux (MF) scan pattern with fore and aft propagating laser beams was applied to the 2 µm DWL. This allows us to measure the vertical wind and the horizontal wind along the flight track simultaneously with a high horizontal resolution of ≈800 m and hence enables us to derive the horizontal MF profile for a broad wavelength spectrum from a few hundred meters to several hundred kilometers. The functionality of this method and the corresponding retrieval algorithm is validated using a comparison against in situ wind data measured by the High Altitude and Long Range (HALO) aircraft which was also deployed in Kiruna for the POLSTRACC (Polar Stratosphere in a Changing Climate) campaign. Based on that, the systematic and random error of the wind speeds retrieved from the 2 µm DWL observations are determined. Further, the measurements performed on that day are used to reveal significant changes in the horizontal wavelengths of the vertical wind speed and of the leg-averaged momentum fluxes in the tropopause inversion layer (TIL) region, which are likely to be induced by interfacial waves as recently presented by Gisinger et al. (2020).</p

Mountain Wave Propagation under Transient Tropospheric Forcing: A DEEPWAVE Case Study

The impact of transient tropospheric forcing on the deep vertical mountain wave propagation is investigated by a unique combination of in-situ and remote-sensing observations and numerical modeling. The temporal evolution of the upstream low-level wind follows approximately a cos2 shape and was controlled by a migrating trough and connected fronts. Our case study reveals the importance of the time-varying propagation conditions in the upper troposphere, lower stratosphere (UTLS). Upper-tropospheric stability, the wind profile as well as the tropopause strength affected the observed and simulated wave response in the UTLS. Leg-integrated along-track momentum fluxes (−MFtrack) and amplitudes of vertical displacements of air parcels in the UTLS reached up to 130 kN m−1 and 1500 m, respectively. Their maxima were phase-shifted to the maximum low-level forcing by ≈ 8 h. Small-scale waves (λx ≈ 20–30 km) were continuously forced and their flux values depended on wave attenuation by breaking and reflection in the UTLS region

Mountain-Wave Propagation under Transient Tropospheric Forcing: A DEEPWAVE Case Study

The impact of transient tropospheric forcing on the deep vertical mountain-wave propagation is investigated by a unique combination of in situ and remote sensing observations and numerical modeling. The temporal evolution of the upstream low-level wind follows approximately a cos2 shape and was controlled by a migrating trough and connected fronts. Our case study reveals the importance of the time-varying propagation conditions in the upper troposphere and lower stratosphere (UTLS). Upper-tropospheric stability, the wind profile, and the tropopause strength affected the observed and simulated wave response in the UTLS. Leg-integrated along-track momentum fluxes (-MFtrack) and amplitudes of vertical displacements of air parcels in the UTLS reached up to 130 kN m-1 and 1500 m, respectively. Their maxima were phase shifted to the maximum low-level forcing by ≈8 h. Small-scale waves (λx ≈ 20 - 30 km) were continuously forced, and their flux values depended on wave attenuation by breaking and reflection in the UTLS region. Only maximum flow over the envelope of the mountain range favored the excitation of longer waves that propagated deeply into the mesosphere. Their long propagation time caused a retarded enhancement of observed mesospheric gravity wave activity about 12–15 h after their observation in the UTLS. For the UTLS, we further compared observed and simulated MFtrack with fluxes of 2D quasi-steady runs. UTLS momentum fluxes seem to be reproducible by individual quasi-steady 2D runs, except for the flux enhancement during the early decelerating forcing phase

Multilevel cloud structures over Svalbard

The presented picture of the month is a superposition of space-borne lidar observations and high-resolution temperature fields of the ECMWF integrated forecast system (IFS). It displays complex tropospheric and stratospheric clouds in the Arctic winter 2015/16. Near the end of December 2015, the unusual northeastward propagation of warm and humid subtropical air masses as far north as 80°N lifted the tropopause by more than 3 km in 24 h and cooled the stratosphere on a large scale. A widespread formation of thick cirrus clouds near the tropopause and of synoptic-scale polar stratospheric clouds (PSCs) occurred as the temperature dropped below the thresholds for the existence of cloud particles. Additionally, mountain waves were excited by the strong flow at the western edge of the ridge across Svalbard, leading to the formation of mesoscale ice PSCs. The most recent IFS cycle using a horizontal resolution of 8 km globally reproduces the large-scale and mesoscale flow features and leads to a remarkable agreement with the wave structure revealed by the space-borne observations

PMC Turbo : Studying Gravity Wave and Instability Dynamics in the Summer Mesosphere Using Polar Mesospheric Cloud Imaging and Profiling From a Stratospheric Balloon

The Polar Mesospheric Cloud Turbulence (PMC Turbo) experiment was designed to observe and quantify the dynamics of small-scale gravity waves (GWs) and instabilities leading to turbulence in the upper mesosphere during polar summer using instruments aboard a stratospheric balloon. The PMC Turbo scientific payload comprised seven high-resolution cameras and a Rayleigh lidar. Overlapping wide and narrow camera field of views from the balloon altitude of ~38 km enabled resolution of features extending from ~20 m to ~100 km at the PMC layer altitude of ~82 km. The Rayleigh lidar provided profiles of temperature below the PMC altitudes and of the PMCs throughout the flight. PMCs were imaged during an ~5.9-day flight from Esrange, Sweden, to Northern Canada in July 2018. These data reveal sensitivity of the PMCs and the dynamics driving their structure and variability to tropospheric weather and larger-scale GWs and tides at the PMC altitudes. Initial results reveal strong modulation of PMC presence and brightness by larger-scale waves, significant variability in the occurrence of GWs and instability dynamics on time scales of hours, and a diversity of small-scale dynamics leading to instabilities and turbulence at smaller scales. At multiple times, the overall field of view was dominated by extensive and nearly continuous GWs and instabilities at horizontal scales from ~2 to 100 km, suggesting sustained turbulence generation and persistence. At other times, GWs were less pronounced and instabilities were localized and/or weaker, but not absent. An overview of the PMC Turbo experiment motivations, scientific goals, and initial results is presented here. © 2019. The Authors

Gravity waves excited during a minor sudden stratospheric warming

An exceptionally deep upper-air sounding launched from Kiruna airport (67.82 degrees N, 20.33 degrees E) on 30 January 2016 stimulated the current investigation of internal gravity waves excited during a minor sudden stratospheric warming (SSW) in the Arctic winter 2015/16. The analysis of the radiosonde profile revealed large kinetic and potential energies in the upper stratosphere without any simultaneous enhancement of upper tropospheric and lower stratospheric values. Upward-propagating inertia-gravity waves in the upper stratosphere and downward-propagating modes in the lower stratosphere indicated a region of gravity wave generation in the stratosphere. Two-dimensional wavelet analysis was applied to vertical time series of temperature fluctuations in order to determine the vertical propagation direction of the stratospheric gravity waves in 1-hourly high-resolution meteorological analyses and short-term forecasts. The separation of upward- and downward-propagating waves provided further evidence for a stratospheric source of gravity waves. The scale-dependent decomposition of the flow into a balanced component and inertia-gravity waves showed that coherent wave packets preferentially occurred at the inner edge of the Arctic polar vortex where a sub-vortex formed during the minor SSW

Clinical Outcomes of 2-Drug Regimens vs 3-Drug Regimens in Antiretroviral Treatment–Experienced People Living With Human Immunodeficiency Virus

BACKGROUND: Limited data exist comparing clinical outcomes of two-drug regimens (2DRs) and three-drug regimens (3DRs) in people living with HIV. METHODS: Antiretroviral treatment-experienced individuals in RESPOND switching to a new 2DR or 3DR from 1/1/12-1/10/18 were included. The incidence of clinical events (AIDS, non-AIDS cancer, cardiovascular disease, end-stage liver and renal disease, death) was compared between regimens using Poisson regression. RESULTS: Of 9791 individuals included, 1088 (11.1%) started 2DRs and 8703 (88.9%) 3DRs. The most common 2DRs were dolutegravir plus lamivudine (22.8%) and raltegravir plus boosted darunavir (19.8%); the most common 3DR was dolutegravir plus 2 nucleoside reverse transcriptase inhibitors (46.9%). Individuals on 2DRs were older (median 52.6 years [interquartile range 46.7-59.0] vs 47.7 [39.7-54.3]), and a higher proportion had ≥1 comorbidity (81.6% vs 73.9%).There were 619 events during 27,159 person-years of follow-up (PYFU): 540 (incidence rate [IR] 22.5/1000 PYFU [95% CI 20.7-24.5]) on 3DRs, 79 (30.9/1000 PYFU [24.8-38.5]) on 2DRs. The most common events were death (7.5/1000 PYFU [95% CI 6.5-8.6]) and non-AIDS cancer (5.8/1000 PYFU [4.9-6.8]). After adjustment for baseline demographic and clinical characteristics, there was a similar incidence of events on both regimen types (2DRs vs 3DRs IR ratio: 0.92 [0.72-1.19]; p=0.53). CONCLUSIONS: This is the first large, international cohort assessing clinical outcomes on 2DRs. After accounting for baseline characteristics, there was a similar incidence of events on 2DRs and 3DRs. 2DRs appear to be a viable treatment option with regard to clinical outcomes; further research on resistance barriers and long-term durability of 2DRs is needed

PMC Turbo: Studying Gravity Wave and Instability Dynamics in the Summer Mesosphere Using Polar Mesospheric Cloud Imaging and Profiling From a Stratospheric Balloon

The Polar Mesospheric Cloud Turbulence (PMC Turbo) experiment was designed to observe and quantify the dynamics of small‐scale gravity waves (GWs) and instabilities leading to turbulence in the upper mesosphere during polar summer using instruments aboard a stratospheric balloon. The PMC Turbo scientific payload comprised seven high‐resolution cameras and a Rayleigh lidar. Overlapping wide and narrow camera field of views from the balloon altitude of ~38 km enabled resolution of features extending from ~20 m to ~100 km at the PMC layer altitude of ~82 km. The Rayleigh lidar provided profiles of temperature below the PMC altitudes and of the PMCs throughout the flight. PMCs were imaged during an ~5.9‐day flight from Esrange, Sweden, to Northern Canada in July 2018. These data reveal sensitivity of the PMCs and the dynamics driving their structure and variability to tropospheric weather and larger‐scale GWs and tides at the PMC altitudes. Initial results reveal strong modulation of PMC presence and brightness by larger‐scale waves, significant variability in the occurrence of GWs and instability dynamics on time scales of hours, and a diversity of small‐scale dynamics leading to instabilities and turbulence at smaller scales. At multiple times, the overall field of view was dominated by extensive and nearly continuous GWs and instabilities at horizontal scales from ~2 to 100 km, suggesting sustained turbulence generation and persistence. At other times, GWs were less pronounced and instabilities were localized and/or weaker, but not absent. An overview of the PMC Turbo experiment motivations, scientific goals, and initial results is presented here