Síndrome de feminización en un perro con un tumor testicular de células de Sertoli

Un perro de 8 años, criptórquido unilateral, se presenta con signos de disuria, alteraciones cutáneas y una masa en abdomen caudal. La ecografía determina la presencia de un quiste prostático y un posible testículo tumoral. Después de la cirugía se realiza histopatología que confirma la preencia de un tumor testicular de cálulas de Sertoli.

Topical 1% cyclosporine eyedrops for the treatment of crystalline corneal dystrophy in dogs

Crystalline corneal dystrophy (CCD) is the most common type of corneal lipidic deposition in dogs. CCD is a primary metabolic disorder of the corneal fibroblast featuring an accumulation of extracellular and intracellular lipid deposits. Corneal lipid deposits create a corneal opacity and modify the interfibrillar collagen distance, inducing light scattering. Corneal vascularization is not usually associated with the disease, but, in case of chronicity, cell death may produce inflammation, and new corneal vessels are developed. To the best of the authors' knowledge, this is the first report of a medical approach for CCD treatment in veterinary medicine. To evaluate the efficacy of topical 1% cyclosporine eyedrops (1% CsA) for the treatment of CCD in dogs. Medical records of dogs with CCD were retrospectively reviewed (2009-2020). Corneal opacification description (COD) [size (mm), depth, and opacification degree (0-3)] was evaluated at 0, 3, 6, 9, 12, and 15 months postinitial diagnosis. Dogs were classified into three groups: the control group (G), the group receiving topical 1% CsA once per day (G), and the group receiving topical 1% CsA twice daily (G). Ninety-two client-owned dogs (163 eyes) of different breeds, ages, and gender fulfilled the inclusion criteria. When compared to G, where the eyes significantly increased COD (p < 0.001), G and Gsignificantly decreased COD (p < 0.001). In fact, the probability of reducing COD was about three times higher in G than in G, being nearly the same for the right [odds ratio (OR) = 2.94; 95% confidence interval (95% CI) = 0.55-15.78] and left eye (OR = 2.92; 95% CI = 0.49-17.26). In addition, for each additional month of treatment in G, the probability of reducing COD increased significantly (OR = 1.12; 95%CI = 1.00-1.26 for the right eye and OR = 1.16; 95%CI = 1.02-1.32 for the left eye). Long-term treatment with topical 1% CsA eyedrops significantly improved CCD in dogs, being the probability of reducing COD higher when applying the treatment twice daily

Therapy of ocular and visceral leishmaniasis in a cat

An 8-year-old, spayed female Domestic Short-haired cat was referred for further evaluation of chronic lymphocytic-plasmacytic stomatitis and bilateral ocular disease. The cat had been treated with systemic glucocorticoids for several months. Initial ophthalmic examination revealed bilateral deep stromal corneal ulcers, exudative panuveitis and secondary glaucoma. Mature mild neutrophilia and monocytosis were detected on complete blood cell count. Abnormalities in the serum profile were hyperglycemia, mild azotemia, hyperglobulinemia and moderate polyclonal gammapathy. Urinalysis revealed glucosuria without ketonuria. Diabetes mellitus was diagnosed and treatment with long-acting insulin was started. An enzyme-linked immunosorbent assay was highly positive for leishmaniasis, and treatment with allopurinol was started. Although specific topical treatment was applied, melting ulcers progressed to corneal perforation and both eyes were enucleated. Ocular histology showed large numbers of intracellular organisms compatible with amastigotes of the genus Leishmania located in the uveal tract, cornea, sclera and retina. Results of inmunohistochemistry staining on ocular samples were positive for Leishmania. Bone marrow cytology demonstrated numerous macrophages with intracytoplasmatic Leishmania. Polymerase chain reaction results on bone marrow for Leishmania were positive. Three weeks later, hypoglycemic episodes permitted withdrawal of the insulin therapy. To the authors' knowledge this is the first case of ocular and visceral leishmaniasis diagnosed in vivo and under systemic treatment in a cat

Claves clínicas para el diagnóstico y tratamiento de las úlceras corneales en el perro

En el perro, las úlceras corneales pueden clasificarse según su gravedad, en úlceras corneales simples y complicadas. En ambos casos la localización y eliminación de la causa es el punto más importante para tener éxito en el tratamiento. La elección de tratamiento médico o quirúrgico dependerá de la etiología, profundidad de la lesión, evolución, y del criterio del oftalmólogo. Este artículo proporciona las claves clínicas para el tratamiento de las úlceras corneales más frecuentes del perro

Palatosquisis en la especie canina

La palatosquisis o paladar secundario hendido es una de las anomalías congénitas más corrientes que presentan los cachorros alnacimiento. Se describen las técnicas más habituales de corrección y la utilizada por los autores.Paiaiosquisis or secondary cleft palate is one of the most frequent congenital abnormalities shown by newborn pups. Commonly used correction techniques and that used by the authors are described

Embolización cartilaginosa en la aorta abdominal secundaria a una lesión arterioesclerótica en la aorta torácica en un perro

Se describe un caso de paraplegia aguda no progresiva en una perra adulta ocasionado por una embolización cartilaginosa en la aorta abdominal cuyo origen se encontraba en una lesión arterioesclerótica en la aorta torácica.