Lockheed modified an fittings for 3,000 psig hydraulic service engineering test report no. 10908

Hydraulic leakage of tube fittings - primary, temperature susceptibility, and deflection leakage test

Technology transfer - A selected bibliography

Selected bibliography on technology transfe

Trees, Forests, and Total Positivity: I. qq-Trees and qq-Forests Matrices

We consider matrices with entries that are polynomials inqarising from naturalq-generalisations of two well-known formulas that count: forests onnvertices withkcomponents; and rooted labelled trees onn+ 1 vertices wherekchildren of the rootare lower-numbered than the root. We give a combinatorial interpretation of thecorresponding statistic on forests and trees and show, via the construction of vari-ous planar networks and the Lindstr ̈om-Gessel-Viennot lemma, that these matricesare coefficientwise totally positive. We also exhibit generalisations of the entriesof these matrices to polynomials ineightindeterminates, and present some conjec-tures concerning the coefficientwise Hankel-total positivity of their row-generatingpolynomials

Climbing the cosmic ladder with stellar twins

Distances to stars are key to revealing a three-dimensional view of the Milky Way, yet their determination is a major challenge in astronomy. Whilst the brightest nearby stars benefit from direct parallax measurements, fainter stars are subject of indirect determinations with uncertainties exceeding 30%. We present an alternative approach to measuring distances using spectroscopically-identified twin stars. Given a star with known parallax, the distance to its twin is assumed to be directly related to the difference in their apparent magnitudes. We found 175 twin pairs from the ESO public HARPS archives and report excellent agreement with Hipparcos parallaxes within 7.5%. Most importantly, the accuracy of our results does not degrade with increasing stellar distance. With the ongoing collection of high-resolution stellar spectra, our method is well-suited to complement Gaia.Comment: published online on MNRA

Inhibition of oncogenic transcription factor REL by the natural product derivative calafianin monomer 101 induces proliferation arrest and apoptosis in human B-lymphoma cell lines

Increased activity of transcription factor NF-κB has been implicated in many B-cell lymphomas. We investigated effects of synthetic compound calafianin monomer (CM101) on biochemical and biological properties of NF-κB. In human 293 cells, CM101 selectively inhibited DNA binding by overexpressed NF-κB subunits REL (human c-Rel) and p65 as compared to NF-κB p50, and inhibition of REL and p65 DNA binding by CM101 required a conserved cysteine residue. CM101 also inhibited DNA binding by REL in human B-lymphoma cell lines, and the sensitivity of several B-lymphoma cell lines to CM101-induced proliferation arrest and apoptosis correlated with levels of cellular and nuclear REL. CM101 treatment induced both phosphorylation and decreased expression of anti-apoptotic protein Bcl-XL, a REL target gene product, in sensitive B-lymphoma cell lines. Ectopic expression of Bcl-XL protected SUDHL-2 B-lymphoma cells against CM101-induced apoptosis, and overexpression of a transforming mutant of REL decreased the sensitivity of BJAB B-lymphoma cells to CM101-induced apoptosis. Lipopolysaccharide-induced activation of NF-κB signaling upstream components occurred in RAW264.7 macrophages at CM101 concentrations that blocked NF-κB DNA binding. Direct inhibitors of REL may be useful for treating B-cell lymphomas in which REL is active, and may inhibit B-lymphoma cell growth at doses that do not affect some immune-related responses in normal cells.R01 GM094551 - NIGMS NIH HHS; P50 GM067041 - NIGMS NIH HHS; GM094551 - NIGMS NIH HHS; R24 GM111625 - NIGMS NIH HHS; GM067041 - NIGMS NIH HH

Comparison of rainfall energy and soil erosion parameters from a rainfall simulator and natural rain

The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file.Title from title screen of research.pdf file (viewed on October 25, 2007)Vita.Includes bibliographical references.Thesis (M.S.) University of Missouri-Columbia 2007.Dissertations, Academic -- University of Missouri--Columbia -- Soil and atmospheric sciences.Numerous studies have used artificial rainfall to quantify relationships for runoff and soil detachment. Application of these results to natural rainfall conditions is dependent in part on how well artificial rainfall mimics these natural conditions. In this study, an optical rainfall imaging system was used to determine the drop-size distributions (DSDs) of natural rain in Missouri. These observations have been compared to those from an indoor gravity rainfall simulator. This thesis reports the results of the DSD intercomparison, where a gamma distribution curve was expected, but a special form of a gamma distribution (exponential distribution) was found. This thesis also explores the impact of the increased velocity of drops due to wind can account for up to one quarter of the total kinetic energy of the rainfall (Helming 2001). However, the results presented here show that about one-half of the total kinetic energy was estimated from horizontal wind, although highly dependent on wind velocity. While there are differences between the shapes of the DSDs, the most significant difference between the natural and simulated rain observed in the cases to date is the temporal variation and the impact of wind that is associated with natural rain

Alcohol: taking a population perspective

Alcohol consumption is a global phenomenon, as is the resultant health, social and economic harm. The nature of these harms varies with different drinking patterns and with the societal and political responses to the burden of harm; nevertheless, alcohol-related chronic diseases have a major effect on health. Strong evidence exists for the effectiveness of different strategies to minimize this damage and those policies that target price, availability and marketing of alcohol come out best, whereas those using education and information are much less effective. However, these policies can be portrayed as anti-libertarian and so viewing them in the context of alcohol-related harm to those other than the drinker, such as the most vulnerable in society, is important. When this strategy is successful, as in Scotland, it has been possible to pass strong and effective legislation, such as for a minimum unit price for alcohol