The CADENCE Pilot Trial – Promoting Physical Activity in Bladder Cancer Survivors: A Protocol Paper

Background: Participation in physical activity has been found to be beneficial for mental and physical health outcomes among cancer survivors. However, to date no intervention exists specifically to promote physical activity among bladder cancer survivors. In light of this knowledge a home-based exercise intervention was co-created for those recently diagnosed with bladder cancer. Aim: The aim of the present study, financially supported by Action Bladder Cancer UK [1], is to pilot the home-based exercise intervention tailored specifically for bladder cancer survivors (i.e. from the point of diagnosis) to improve physical and mental health outcomes (during treatment and beyond) in this population. Methods: This study will use a randomised controlled trial design. Arm one will consists of the 14 week home-based exercise intervention and arm two usual care (15 participants will be randomised to each arm). Baseline data collection will take place shortly after clinical diagnosis of bladder cancer, and follow-up approximately 7 weeks and then again approximately 14 weeks after commencement of the intervention. At each data collection point data will be collected from participants relating to demographics, physical and mental health. Participants will aslo be asked to wear an Actigraph Accelerometer at each data collection point for seven consecutive days. Immediately after baseline data collection participants in the intervention arm will be given the home-based exercise booklet. Ethics and dissemination: Ethical approval was obtained for the present study via The London- City and East Research Ethics Committee (ID:291676). Results of this study will be disseminated through peer-reviewed publications and scientific presentations

Chronic Skin Disease and Levels of Physical Activity in 17,777 Spanish Adults: A Cross-Sectional Study

Background: To date there is limited literature on the prevalence of chronic skin conditions and levels of physical activity (PA) in Spain. Aim: The present study aims to (i) determine the prevalence of chronic skin disease and (ii) compare levels of PA in those with chronic skin disease to those without in a large representative sample of Spanish adults aged 15‐69 years. Methods: Data from the Spanish National Health Survey 2017 were analysed. Chronic skin disease was assessed using a yes‐no question. PA was measured using the short form of the International Physical Activity Questionnaire (IPAQ). Total PA metabolic equivalent of task (MET)‐minutes/week were calculated, and PA was included in the analyses as a continuous and a five‐category variable. Results: This cross‐sectional study included 17,777 participants [52.0% women; mean (standard deviation) age 45.8 (14.1) years]. There were 940 (5.3%) adults with chronic skin disease. After adjusting for several potential confounders, there was a negative association between chronic skin disease and PA [odds ratio (OR)=0.87, 95% CI=0.76–1.00]. The association was significant in men (OR=0.76, 95% CI=0.62‐0.93) but not in women (OR=0.97, 95% CI=0.81‐1.16). Conclusions: In this large representative sample of Spanish adults, the prevalence of chronic skin disease was low. Levels of PA in men with chronic skin conditions, but not in women, were lower than those without

Prevalence and correlates of exercise addiction in the presence vs absence of indicated eating disorders

Despite the many benefits of regular, sustained exercise, there is evidence that exercise can become addictive, to the point where the exerciser experiences negative physiological and psychological symptoms, including withdrawal symptoms upon cessation, training through injury and the detriment of social relationships. Furthermore, recent evidence suggests that the aetiology of exercise addiction is different depending on the presence or absence of eating disorders. The aim of this study was to explore what extent was eating disorder status, body dysmorphic disorder, reasons for exercise, social media use and fitness instructor status were associated with exercise addiction, and to determine differences according to eating disorder status. The key findings showed that the aetiology of exercise addiction differed according to eating disorder status, with variables including social media use, exercise motivation and ethnicity being uniquely correlated with exercise addiction only in populations with indicated eating disorders. Furthermore, body dysmorphic disorder was highly prevalent in subjects without indicated eating disorders, and could be a primary condition in which exercise addiction is a symptom. It is recommended that clinicians and practitioners working with patients who present with symptoms of exercise addiction should be screened for eating disorders and body dysmorphic disorder before treatments are considered