Endoscopic Full-Thickness Resection of Synchronous Adenocarcinomas of the Distal Rectum

Endoscopic full-thickness resection (EFTR) with an innovative full-thickness resection device (FTRD; Ovesco Endoscopy, Tübingen, Germany) allows a safe and complete full-thickness resection of early colorectal cancer. We present the first case of two EFTR performed at the same time to treat synchronous rectal adenocarcinomas

Endoscopic Resection of a Giant Pedunculated Leiomyoma of the Sigmoid Colon

The leiomyoma is a benign smooth muscle tumor and may occur throughout the entire digestive tract, more frequently in the stomach, and small intestine, but is rarely seen in large bowel. Furthermore, a colonic giant pedunculated leiomyoma is very rare. The traditional management option for a colonic leiomyoma is surgical resection. However, the endoloop‑assisted polypectomy could be the treatment of choice even for very large lesions

Superficial neoplasia involving the Ileocecal valve: Clinical outcomes of endoscopic submucosal dissection

BACKGROUND: Endoscopic submucosal dissection (ESD) is the treatment of choice for colorectal superficial neoplasia, but certain anatomical locations are challenging even for skilled endoscopists. Ileocecal valve (ICV) is considered a technically challenging site for ESD. OBJECTIVE: Aim of this study was to analyze efficacy and safety of Endoscopic Submucosal Dissection in the treatment of colorectal neoplasia involving the ileocecal valve (ICV) DESIGN: Retrospective study. PATIENTS: We retrospectively evaluated 1507 consecutive patients undergoing ESD at two tertiary referral centres for ESD (Italy and Japan) from January 2008 to March 2020. MAIN OUTCOME MEASURES: Demographic, clinical, procedural, and follow-up data was collected, analysed, and compared between patients with ileocecal valve lesions (ICVL) and patients with non-ICVL. RESULTS: Overall, 1507 patients were enrolled (872 M, 57.8%), of these 53 patients had lesions involving the ICV. Mean age was 70.2 years (range, 53-83 years). En-bloc resection was achieved in 52 (98%) patients. The median specimen size of ICVL was 36.4 mm (range, 8-80 mm), significantly smaller than non-ICVL (p = 0.005). Procedure time was significantly longer in the ICVL group, (71.3 vs. 58.9 min; p = 0.03). Non Granular Type Laterally Spreading Tumors (LST-NG) were significantly more frequent in the ICVL group compared to rectum (52.8% vs. 25.7; p = 0.0001). En-bloc resection rate in the ileocecal region did not differ significantly between groups (p = 0.20). Complications such as perforation and postoperative occurred respectively in 3/53 (5.7%) and 1/53 (2%) patient, and were treated conservatively. At first surveillance colonoscopy performed at 6 months, recurrent adenoma was detected in 2/53 patients (3.9%). CONCLUSIONS: ESD is safe and effective for the treatment of colorectal neoplasia involving the ileocecal valve if performed by expert endoscopist in referral centres

Giant arteriovenous malformation of the colon mimicking lipoma

Giant arteriovenous malformation of the colon mimicking lipom