43 research outputs found
Lettura di due prose liriche reboriane: Stralcio e Perdono
La questione filologica e cronologica relativa a un «volume di poesie-prosa » sulla guerra, progettato e mai ultimato da Clemente Rebora, è stata presentata e indagata nel modo più completo in un lavoro di Attilio Bettinzoli del 2002, dal quale ogni ulteriore ricognizione e ipotesi deve prendere le mosse: ad esso si rinvia per la definizione generale del problema. Problema se non vera e propria crux, a meno di un improbabile e cospicuo affioramento di nuove carte reboriane, la ricostruzione congetturale del progetto del libro deve fondarsi sui pochi ma estremamente significativi testi sparsi stampati tra il 1916 e il 1920 su riviste quali «La Brigata», «La Riviera Ligure», «La Tempra», «La Diana », «La Raccolta», «Rivista di Milano», e sui brani epistolari nei quali l’autore lascia filtrare notizie riguardanti il volume.Il progetto fu concepito, elaborato e abbandonato «tra l’estate del 1916 e i primi mesi del 1917» (BETTINZOLI 2002, p. 63), anche se è probabile che i primi impulsi a scrivere per testimoniare l’orrenda realtà della guerra risalgano già al 1915 (è questo l’anno in cui Rebora, richiamato alle armi, combatte sul fronte goriziano e viene congedato per un grave trauma nervoso seguìto allo scoppio ravvicinato di un obice da 305, pochi giorni prima del Natale). Diceva infatti il poeta all’amica Lavinia Mazzucchetti in una lettera dalla zona di guerra datata 3 dicembre 1915: «Si vive e si muore come uno sputerebbe: i cadaveri insepolti, come una pratica non emarginata – il tutto in una esasperazione militaresca in débacle. Non so più scrivere né esprimere: saprò – non che voglia – quando canterò, perché non intendo morire»
L’odore del sangue di Goffredo Parise: fascinazione della gioventù, tentazioni di un reporter
1. Uno dei pochi margini di discussione lasciati da Cesare Garboli nella sua esauriente Prefazione a L’odore del sangue, il romanzo postumo di Goffredo Parise, riguarda l’interpretazione di un tratto fondamentale dell’opera. Il ragazzo di cui Silvia s’innamora tradendo il marito Filippo, il giovane violento e senza volto che incarna in breve l’ossessione di Filippo, è fascista. Costituzionalmente fascista, si direbbe, dal momento che questa connotazione politica precede nel romanzo ogni sua d..
Il rombo dall’«Emilia Paranoica». Altri libertini di Tondelli
È un dato acquisito, per merito di molti lettori di Tondelli, che la cifra violenta condensata da Altri libertini sia frutto di una reazione ad un contesto sociale e culturale inibente nei confronti della vita, claustrofobico: da vari racconti affiora nettamente l’idiosincrasia che oppone i personaggi – e lo stesso autore – alle piccole patrie-prigione di Reggio Emilia, Correggio, Modena, Parma. Persino il titolo manifesta con poche possibilità di fraintendimento la dimensione fondante dell’«..
Endometriosis: 10 keys points for MRI
Endometriosis is a chronic disease and a clinical problem in women of fertile age, with a high impact on quality of
life, work productivity and health care management.
Two imaging modalities are employed in the diagnosis and evaluation of extent of disease: ultrasound examination
with endovaginal approach and magnetic resonance imaging (MRI). MRI, thanks to its high contrast and
resolution characteristics, offers a high level of accuracy in the study of endometriosis and adenomyosis.
We illustrate here 10 key MRI points for the detection and diagnosis of endometriosis
Dandy-Walker malformation: is the "tail sign" the key sign?
OBJECTIVE.To demonstrate the value of the "tail sign" in the assessment of Dandy-Walker Malformation (DWM).
METHODS:
A total of 31fetal MRI, performed before 24 weeks of gestation after second-line US examination between May 2013 and September 2014, were examined retrospectively. All MRI examinations were performed using a 1.5 Tesla magnet without maternal sedation.
RESULTS:
MRI diagnosed 15/31 cases of Dandy-Walker Malformation, 6/31 cases of vermian partial caudal agenesis, 2/31 of vermian hypoplasia, 4/31 of vermian malrotation, 2/31 of Walker-Warburg Syndrome, 1/31 of Blake pouch cyst, 1/31 of rhombencephalosynapsis. All data were compared with fetopsy results, Fetal MR after the 30th week or postnatal MRI; the follow up depended on the maternal decision to terminate or continue pregnancy. In our review study we found the presence of the "tail sign"; this sign was visible only in Dandy-Walker Malformation and Walker-Warburg Syndrome.
CONCLUSION:
The "tail sign" could be helpful in the difficult differential diagnosis between Dandy Walker, vermian malrotation, vermian hypoplasia and vermian partial agenesis
Role of fetal MRI in the evaluation of isolated and non-isolated corpus callosum dysgenesis: results of a cross-sectional study
PURPOSE:
The aims of this study were to characterize isolated and non-isolated forms of corpus callosum dysgenesis (CCD) at fetal magnetic resonance imaging (MRI) and to identify early predictors of associated anomalies.
METHODS:
We retrospectively analyzed 104 fetuses with CCD undergoing MRI between 2006 and 2016. Corpus callosum, cavum septi pellucidi, biometry, presence of ventriculomegaly, gyration anomalies, cranio-encephalic abnormalities and body malformations were evaluated. Results of genetic tests were also recorded.
RESULTS:
At MRI, isolated CCD was 26.9%, the rest being associated to other abnormalities. In the isolated group, median gestational age at MRI was lower in complete agenesis than in hypoplasia (22 vs 28 weeks). In the group with additional findings, cortical dysplasia was the most frequently associated feature (P = 0.008), with a more frequent occurrence in complete agenesis (70%) versus other forms; mesial frontal lobes were more often involved than other cortical regions (P = 0.006), with polymicrogyria as the most frequent cortical malformation (40%). Multivariate analysis confirmed the association between complete agenesis and cortical dysplasia (odds ratio = 7.29, 95% confidence interval 1.51-35.21).
CONCLUSIONS:
CCD is often complicated by other intra-cranial and extra-cranial findings (cortical dysplasias as the most prevalent) that significantly affect the postnatal prognosis. The present study showed CCD with associated anomalies as more frequent than isolated (73.1%). In isolated forms, severe ventriculomegaly was a reliable herald of future appearance of associated features
Dynamics of Viral Infection and Evolution of SARS-CoV-2 Variants in the Calabria Area of Southern Italy
In this study, we report on the results of SARS-CoV-2 surveillance performed in an area of Southern Italy for 12 months (from March 2021 to February 2022). To this study, we have sequenced RNA from 609 isolates. We have identified circulating VOCs by Sanger sequencing of the S gene and defined their genotypes by whole-genome NGS sequencing of 157 representative isolates. Our results indicated that B.1 and Alpha were the only circulating lineages in Calabria in March 2021; while Alpha remained the most common variant between April 2021 and May 2021 (90 and 73%, respectively), we observed a concomitant decrease in B.1 cases and appearance of Gamma cases (6 and 21%, respectively); C.36.3 and Delta appeared in June 2021 (6 and 3%, respectively); Delta became dominant in July 2021 while Alpha continued to reduce (46 and 48%, respectively). In August 2021, Delta became the only circulating variant until the end of December 2021. As of January 2022, Omicron emerged and took over Delta (72 and 28%, respectively). No patient carrying Beta, Iota, Mu, or Eta variants was identified in this survey. Among the genomes identified in this study, some were distributed all over Europe (B1_S477N, Alpha_L5F, Delta_T95, Delta_G181V, and Delta_A222V), some were distributed in the majority of Italian regions (B1_S477N, B1_Q675H, Delta_T95I and Delta_A222V), and some were present mainly in Calabria (B1_S477N_T29I, B1_S477N_T29I_E484Q, Alpha_A67S, Alpha_A701S, and Alpha_T724I). Prediction analysis of the effects of mutations on the immune response (i.e., binding to class I MHC and/or recognition of T cells) indicated that T29I in B.1 variant; A701S in Alpha variant; and T19R in Delta variant were predicted to impair binding to class I MHC whereas the mutations A67S identified in Alpha; E484K identified in Gamma; and E156G and ΔF157/R158 identified in Delta were predicted to impair recognition by T cells. In conclusion, we report on the results of SARS-CoV-2 surveillance in Regione Calabria in the period between March 2021 and February 2022, identified variants that were enriched mainly in Calabria, and predicted the effects of identified mutations on host immune response