16 research outputs found
The TOTEM Experiment at the CERN Large Hadron Collider
Get PDFThe TOTEM Experiment will measure the total pp cross-section with the luminosity independent method and study elastic and diffractive scattering at the LHC. To achieve optimum forward coverage for charged particles emitted by the pp collisions in the interaction point IP5, two tracking telescopes, T1 and T2, will be installed on each side in the pseudorapidity region 3,1 <h< 6,5, and Roman Pot stations will be placed at distances of 147m and 220m from IP5. Being an independent experiment but technically integrated into CMS, TOTEM will first operate in standalone mode to pursue its own physics programme and at a later stage together with CMS for a common physics programme. This article gives a description of the TOTEM apparatus and its performance
Meal use of premixed insulin analogs vs. human regular insulins improves life quality in healthy T1DM basally treated with insulin glargine or detemir
No full textDiffusion-weighted 3T MR imaging with b-multiple SE- EPI in the differential diagnosis of cystic pancreatic lesions
No full textPERMANENT PACING:“OPTIMAL” A-V DELAY SELECTED BY ECHO-COLOR-DOPPLER EVALUATION OF COMMON CAROTID ARTERY FLOW.
No full textIncidental findings in preoperative chest radiograph: is it an effective tool on patient outcome?
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Valutazione ecocardiografica sotto sforzo della funzione ventricolare sinistra nelle miocardiopatie dilatative
No full textEvaluation of taxol cardiotoxicity in metastatic breast cancer.
No full textCardiac safet of taxol has been documente
Matrix metalloproteinases and airway remodeling and function in primary ciliary dyskinesia
No full textBACKGROUND: The balance between matrix metalloproteinases (MMPs) and their tissue
inhibitors (TIMPs) is important in the regulation of airway damage.
OBJECTIVE: To evaluate whether they are important in the pathophysiology of
primary and secondary ciliary dyskinesia (PCD, SCD).
METHODS: We measured sputum bacteriology, lung CT changes, MMPs, TIMPs and lung
function in 86 patients (51 PCD, 35 SCD) in a cross-sectional study; the 10
controls studied did not have HRCT or sputum cultures. MMPs, TIMPs and lung
function were evaluated longitudinally for up to one year in 38 PCD patients.
RESULTS: At baseline, there were no differences in MMPs, TIMPs and MMPs/TIMPs,
between PCD and SCD but lower levels were found in controls. There was an
association between poorer lung function with increasing levels of MMPs in PCD,
while in SCD only MMP-9/TIMP-1 values correlated with FRC z-scores. Levels of
MMPs and TIMPs significantly correlated with severity HRCT changes.
Longitudinally, there were significant correlations between slope of changes in
spirometric parameters and slope of change in sputum MMPs in PCD patients.
CONCLUSIONS: In conclusion, we report for the first time that increased MMPs are
associated with worse airway damage in PCD and SCD, and thus are potential
therapeutic targets
