Clustering and Combining Pattern of High-Risk Behaviors among Iranian University Students: A Latent Class Analysis

Background: High-risk behaviors are increasing among young adults worldwide. We aimed to identify university students’ subgroups on the basis of high-risk behaviors and to assess the role of age, living alone, religious beliefs, and parental support in the membership of specific subgroups. Study design: A cross-sectional study Methods: The study was conducted in Bushehr (the south of Iran) from November to December 2016. The sample included 977 university students selected through random sampling. The data were collected using a self-administered questionnaire. Then, latent class analysis was used to classify the students. Results: Totally, five latent classes were identified as follows: low risk, high risk, somewhat low risk, hookah user, and very high risk. Notably, 7.7% and 2.5% of the students belonged to high risk and very high risk classes, respectively. The results suggested the protective effect of familial support and religiosity on high-risk behaviors. Conclusions: This study indicated the co-occurrence of high-risk behaviors. The findings can be used to plan and evaluate interventions by considering risk factors and protective factors in universities

Comparison Of Chemical Profiles Of Black Cumin Seed (Nigella Sativa .L) Extracts And Evaluation Of Their Cytotoxic Effect On Breast Cancer Mcf-7 And Mda-Mb- 231 Cell Lines

Breast cancer is one of the main life-threatening diseases that a woman may have to face during her lifetime. This study was proposed in order to investigate the anticancer effects of the active ingredients of Nigella sativa crude extract, Thymoquinone (TQ), and Linoleic Acid (LA) on breast cancer MCF-7 and MDAMB- 231 cell lines. According to study design of this research, the study was performed in two parts respectively: 1. Extraction and Identification of Nigella sativa composition The main objective of this part of the present study was to compare the extract and oil composition of Iranian and Indian Nigella sativa L. extracted, using Super Critical Fluid Extraction (SFE) and solvent extraction

Cigarette smoking and its relationship with perceived familial support and religiosity of university students in Tabriz

Objective: The goal of the present study was to assess the prevalence of cigarette smoking and its relationship to other risk taking behaviors, perceived familial support and religiosity among college students in Tabriz, Iran . Method: In this study, 1837 randomly selected students participated and completed a self-administered questionnaire inquiring demographic characteristics, risk taking behaviors, Aneshensel and Sucoff's 13-items one-dimensional perceived Parental support scale and 28 - items Kendler's general religiosity scale. Results: In general, 15.8 of the students were cigarette smokers. The results indicated that being male (OR = 3.21), living alone or with friends (OR = 2.00), having a part-time job (OR = 1.98), alcohol consumption during the past 30 days (OR = 3.67), hookah use (OR = 5.23), substance abuse (OR = 1.69), familial support (OR = 0.97) and religiosity (OR = 0.98) have statistically significant relationships with cigarette smoking . Conclusion: Our study represents the co-occurrence of risky behaviors. Cultural context in the traditional communities seems to show the crucial role of familial support and religiosity traits with the female gender as predictive factors to not smoke cigarette and perform other risky behaviors

Case Fatality Rate of COVID-19: A Systematic Review and Meta-Analysis

Objective: The ongoing novel coronavirus disease 2019 (COVID-19) is the main cause of morbidity and mortality due to its contagious nature and absence of vaccine and treatment. Although there are considerable primary studies that reported extremely variable case fatality rate (CFR) of COVID-19, there is no review study that attempted to estimate CFR of COVID-19. The current systematic review and meta-analysis was aimed to estimate the pooled CFR of COVID-19. Methods: Electronic databases: PubMed, Science Direct, Scopus and Google Scholar were searched to retrieve the eligible primary studies that reported CFR of COVID-19. Keywords: ("COVID-19"OR "COVID-2019" OR "severe acute respiratory syndrome coronavirus 2"OR "severe acute respiratory syndrome coronavirus 2" OR "2019-nCoV" OR "SARS-CoV-2" OR "2019nCoV" OR (("Wuhan" AND ("coronavirus" OR "coronavirus")) AND (2019/12[PDAT] OR 2020[PDAT]))) AND ("mortality "OR "mortality" OR ("case" AND "fatality" AND "rate") OR "case fatality rate") were used as free text and MeSH term in searching process. Random-effects model used to estimate the CFR in this study. I2 statistic, Cochran’s Q test and T2 were used to assess the available heterogeneity between included studies. Results: The overall pooled CFR of COVID 19 was 10.0 %( 95% CI: 8.0-11.0); P<0.001; I2 = 99.7). The pooled CFR of COVID 19 in general population was 1.0% (95% CI: 1.0–3.0); P<0.001; I2 = 94.3), while in hospitalized patients was 13.0 % (95% CI: 9.0–17.0); P<0.001, I2 = 95.6). The pooled CFR in patients admitted in intensive care unit (ICU) was 37.0 % (95% CI: 24.0–51.0); P<0.001, I2 = 97.8) and in patients older than 50 years was 19.0 % (95% CI: 13.0–24.0); P<0.001; I2 = 99.8). Conclusion: The present review results highlighted the need of transparency in testing and reporting policies and denominators used in CFR estimation. It is also necessary reporting the cases age, sex and the comorbidity distribution of all patients which important in comparing the CFR among different segments of population

Epidemiological characteristics of human brucellosis in Shahin Dezh, Western Azarbaijan, Iran, 2008-2012

Background: Brucellosis is still one of the most challenging issues for health and the economy in many developing countries such as Iran. Objectives: This study investigated the epidemiological features of brucellosis in Shahin Dezh, Western Azarbaijan province, North West of Iran. Patients and Methods: This study had across-sectional design and data was collected from private and public sectors over a five-year period (2008-2012). All cases were studied between years 2008 and 2012 in Shahin Dezh. Results: In total, 492 cases of brucellosis were reported. The prevalence of brucellosis decreased from 152 cases/100000 inhabitants in 2008 to 97 cases/100000 inhabitants at the beginning of 2012. About 52.3 of subjects were male, and most cases of brucellosis were aged 25-30 years. Eighty-one percent of subjects lived in rural areas. There was a statistically significant difference regarding contact with livestock between rural and urban areas (91.7 vs. 68.8) (P value <0.001). Raw milk was the most commonly consumed dairy product; consumed by 37 of cases. Finally, during winter and spring a high prevalence rate of brucellosis was reported. Conclusions: Comprehensive health-related interventions need to empower communities at risk, especially young men and young and adult women in the Shahin Dezh County. Health education is needed to raise awareness of people in the studied area. © 2015, Infectious Diseases and Tropical Medicine Research Center

Comparison of sf-36 and whoqol-bref in measuring quality of life in patients with type 2 diabetes

Peer reviewedPublisher PD

Prevalence of cigarette smoking and its related factors among Iranian

Background: Smoking is considered as the second leading risk factor of early death and disability throughout the world. Smoking is the second leading risk factor of early death and disability in the world. The workplace is an important setting for the implementation of cigarette smoking prevention and control interventions. This study aimed to determine the prevalence of cigarette smoking and related factors by focusing on ADHD and risk-taking behaviors among a sample of Iranian workers. Methods: This cross-sectional study was conducted on 2434 male workers of Kaveh Industrial City in Saveh. Random cluster sampling was used in the selection of workers. All workers completed five sets of anonymous and validated questionnaires. ADHD was measured by Conner�s Adult ADHD Rating Scales. Data analysis was done using chi-square, independent t-test and logistic regression model in STATA 10. Also, P-value < 0.05 was considered statistically significant. Results: The mean age of the workers was 32.80±7.05 years. The prevalence of cigarette smoking in the lifetime, last year, last month, and daily or almost daily in the last month were 26.2, 20 6, 18.5, and 13.1 respectively. After adjustment, age (OR=1.08), sensation seeking (OR=1.57), hookah smoking (OR=4.21), alcohol use (OR=2.51), sexual risk behaviors (OR=2.25), religiosity (OR=0.95) and self-esteem (OR=2.02) were associated with cigarette smoking. Conclusion: Our results showed that 13.1 of workers were regular smokers (daily or almost daily). Specific programs in workplaces, including interventions to enhance self-steam and reduce anxiety, can be effective in lowering cigarette smoking prevalence. Also, comprehensive interventions to reduce or prevent different risk-taking behaviors can be considered as elements of preventive action plans. © 202