Public Relations: A role for women?

In an effort to seek coherence, continuity and connection in the communication discipline, this paper explores the issue of gender and culture within the field of public relations. This paper examines how gender affects the disciplinary detachment of public relations from the many communication disciplines. Secondary research that has emerged over the last 25 years is analyzed by discussing the feminization and perspectives of gender’s influence in the discipline of public relations. Future opportunities for both universities and the industry are explored, in order to help bridge the gap of detachment of public relations to that of similar disciplines

Roundtable Discussion Examining Ritual, Technology, and Community in Urban Communication

Pervasive technologies that now exist in the urban setting have greatly improved the ability to connect on a macro-level, but have minimized the intimate shared experience of community on a micro level. This paper explores how technology has changed rituals within the global community and has contributed new methods to the process of human interaction. Technology’s influence on civic engagement, business meetings, shopping and socializing are examined to assess the impact technology has on human connections

Improving the First Impression of an Online Scientific Publishing Service: A Usability Test

A study of the Human-Oriented Technology Lab at Carleton University shows that users form an opinion (first impression) regarding a new website in 50 milliseconds (Lindgaard et al (2006)). Furthermore, the Halo effect causes that the first impression will be transferred on the whole organization. For this reason, it is very important to optimize a website before one starts with marketing activities. There is no thing as a second first impression. In this contribution, we analyse the website of a new scientific journal. The usability test covers 2 areas: The layout and the functionality of the website on a variety of devices (mobile devices (Android, iOS), Macs, PCs with different browsers)

The Impact of the General Data Protection Regulation on the Design and Measurement of Marketing Activities: Introducing Permission Marketing and Tracking for Improved Marketing & CRM Compliance with Legal Requirements

It is important to design marketing and CRM campaigns in accordance with the customer’s requirements. A good way to collect information for the creation of a purposeful campaign is the usage of feedback and knowledge of previous campaigns. But the introduction of the GDPR 2016/679 in May 2018 makes the measurement of consumer behavior in a law-conforming way more challenging. This contribution discusses user behavior measurement methods which are compatible with the GDPR. It illustrates the impact of the new regulation on user communication in the context of email campaigns and of social media marketing in Facebook. We show that the implementation of Godin’s permission marketing approach is a blueprint for GDPR compatible marketing communication activities (Godin, 1999)

Classroom to Boardroom: The Role of Gender in Leadership Style, Stereotypes and Aptitude for Command in Public Relations

This study uses scholarly literature grounded in organizational communication theory, feminist perspectives and gender theory on the public relations industry to provide a theoretical framework for primary research conducted on both undergraduate public relations majors and public relations practitioners. Results from primary research (interviews with undergraduate students and a survey administered to public relations practitioners) reveals parallels and disconnects between student expectations and professional realities of the role gender plays in the public relations discipline. To help foster diversity and reduce gendered stereotypes within undergraduate public relations programs and the public relations industry fresh, pedagogical recommendations are explored. Cameron, Lariscy, and Sweep (1992) found that education influences the way public relations is practiced. Thus, with pedagogical changes at the undergraduate level, there is hope for a rebalance of equal gender distribution for female practitioners at all professional levels, as well the capacity to provide more comprehensive and accurate images of the discipline

Restoration of Sp4 in Forebrain GABAergic Neurons Rescues Hypersensitivity to Ketamine in Sp4 Hypomorphic Mice.

BackgroundKetamine produces schizophrenia-like behavioral phenotypes in healthy people. Prolonged ketamine effects and exacerbation of symptoms after the administration of ketamine have been observed in patients with schizophrenia. More recently, ketamine has been used as a potent antidepressant to treat patients with major depression. The genes and neurons that regulate behavioral responses to ketamine, however, remain poorly understood. Sp4 is a transcription factor for which gene expression is restricted to neuronal cells in the brain. Our previous studies demonstrated that Sp4 hypomorphic mice display several behavioral phenotypes relevant to psychiatric disorders, consistent with human SP4 gene associations with schizophrenia, bipolar disorder, and major depression. Among those behavioral phenotypes, hypersensitivity to ketamine-induced hyperlocomotion has been observed in Sp4 hypomorphic mice.MethodsIn the present study, we used the Cre-LoxP system to restore Sp4 gene expression, specifically in either forebrain excitatory or GABAergic inhibitory neurons in Sp4 hypomorphic mice. Mouse behavioral phenotypes related to psychiatric disorders were examined in these distinct rescue mice.ResultsRestoration of Sp4 in forebrain excitatory neurons did not rescue deficient sensorimotor gating nor ketamine-induced hyperlocomotion. Restoration of Sp4 in forebrain GABAergic neurons, however, rescued ketamine-induced hyperlocomotion, but did not rescue deficient sensorimotor gating.ConclusionsOur studies suggest that the Sp4 gene in forebrain GABAergic neurons regulates ketamine-induced hyperlocomotion

Factor analysis of attentional set-shifting performance in young and aged mice

<p>Abstract</p> <p>Background</p> <p>Executive dysfunction may play a major role in cognitive decline with aging because frontal lobe structures are particularly vulnerable to advancing age. Lesion studies in rats and mice have suggested that intradimensional shifts (IDSs), extradimensional shifts (EDSs), and reversal learning are mediated by the anterior cingulate cortex, the medial prefrontal cortex, and the orbitofrontal cortex, respectively. We hypothesized that the latent structure of cognitive performance would reflect functional localization in the brain and would be altered by aging.</p> <p>Methods</p> <p>Young (4 months, n = 16) and aged (23 months, n = 18) C57BL/6N mice performed an attentional set-shifting task (ASST) that evaluates simple discrimination (SD), compound discrimination (CD), IDS, EDS, and reversal learning. The performance data were subjected to an exploratory factor analysis to extract the latent structures of ASST performance in young and aged mice.</p> <p>Results</p> <p>The factor analysis extracted two- and three-factor models. In the two-factor model, the factor associated with SD and CD was clearly separated from the factor associated with the rest of the ASST stages in the young mice only. In the three-factor model, the SD and CD loaded on distinct factors. The three-factor model also showed a separation of factors associated with IDS, EDS, and CD reversal. However, the other reversal learning variables, ID reversal and ED reversal, had somewhat inconsistent factor loadings.</p> <p>Conclusions</p> <p>The separation of performance factors in aged mice was less clear than in young mice, which suggests that aged mice utilize neuronal networks more broadly for specific cognitive functions. The result that the factors associated with SD and CD were separated in the three-factor model may suggest that the introduction of an irrelevant or distracting dimension results in the use of a new/orthogonal strategy for better discrimination.</p

Transplantation of schistosome sporocysts between host snails: A video guide.

Schistosomiasis is an important parasitic disease, touching roughly 200 million people worldwide. The causative agents are different Schistosoma species. Schistosomes have a complex life cycle, with a freshwater snail as intermediate host. After infection, sporocysts develop inside the snail host and give rise to human dwelling larvae. We present here a detailed step-by-step video instruction in English, French, Spanish and Portuguese that shows how these sporocysts can be manipulated and transferred from one snail to another. This procedure provides a technical basis for different types of ex vivo modifications, such as those used in functional genomics studies

Transplantation of schistosome sporocysts between host snails::A video guide

Schistosomiasis is an important parasitic disease, touching roughly 200 million people worldwide. The causative agents are different Schistosoma species. Schistosomes have a complex life cycle, with a freshwater snail as intermediate host. After infection, sporocysts develop inside the snail host and give rise to human dwelling larvae. We present here a detailed step-by-step video instruction in English, French, Spanish and Portuguese that shows how these sporocysts can be manipulated and transferred from one snail to another. This procedure provides a technical basis for different types of ex vivo modifications, such as those used in functional genomics studies

Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production

α-galactosidase (α-GAL) and α-N-acetylgalactosaminidase (α-NAGAL) are two glycosyl hydrolases responsible for maintaining cellular homeostasis by regulating glycan substrates on proteins and lipids. Mutations in the human genes encoding either enzyme lead to neurological and neuromuscular impairments seen in both Fabry- and Schindler/Kanzaki- diseases. Here, we investigate whether the parasitic blood fluke Schistosoma mansoni, responsible for the neglected tropical disease schistosomiasis, also contains functionally important α-GAL and α-NAGAL proteins. As infection, parasite maturation and host interactions are all governed by carefully-regulated glycosylation processes, inhibiting S. mansoni’s α-GAL and α-NAGAL activities could lead to the development of novel chemotherapeutics. Sequence and phylogenetic analyses of putative α-GAL/α-NAGAL protein types showed Smp_089290 to be the only S. mansoni protein to contain the functional amino acid residues necessary for α-GAL/α-NAGAL substrate cleavage. Both α-GAL and α-NAGAL enzymatic activities were higher in females compared to males (p α-GAL), which was consistent with smp_089290’s female biased expression. Spatial localisation of smp_089290 revealed accumulation in parenchymal cells, neuronal cells, and the vitellaria and mature vitellocytes of the adult schistosome. siRNA-mediated knockdown (>90%) of smp_089290 in adult worms significantly inhibited α-NAGAL activity when compared to control worms (siLuc treated males, p<0.01; siLuc treated females, p<0.05). No significant reductions in α-GAL activities were observed in the same extracts. Despite this, decreases in α-NAGAL activities correlated with a significant inhibition in adult worm motility as well as in egg production. Programmed CRISPR/Cas9 editing of smp_089290 in adult worms confirmed the egg reduction phenotype. Based on these results, Smp_089290 was determined to act predominantly as an α-NAGAL (hereafter termed SmNAGAL) in schistosome parasites where it participates in coordinating movement and oviposition processes. Further characterisation of SmNAGAL and other functionally important glycosyl hydrolases may lead to the development of a novel anthelmintic class of compounds