41 research outputs found

    Geometry and procedure for benchmarking SFF and hybrid fabrication process resolution

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    ABSTRACT Since the advent of SFF and RP a number of SFF benchmarking geometries and methodologies have been developed and employed with some similarities but limited standardization. Minimal information has been published in regard to a standard method of measuring the resolution limits or capabilities of SFF and SFF-based hybrid processes. In an effort to benchmark resolution limits of SFF and Hybrid Fabrication processes, several benchmarking geometries were developed to capture the resolution capabilities, specifically hole size and rod size range, of multiple hybrid fabrication path steps and a hybrid path as a whole. These useful geometries are shared with the SFF community and procedures for their use are described in this paper

    Antimicrobial Activity of two Mentha Species Essential Oil and its Dependence on Different Origin and Chemical Diversity

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    Genus Mentha presents group of plants which are the most studied in family Lamiaceae. Aboveground parts are used for different purposes in pharmacy, food industry or confectionery. Most important is natural product extracted from leaves - essential oil (EO). The aim of presented experiment was to demonstrate different chemotype and compare antibacterial activity of two Mentha species EO. Plant samples were obtained from various environments – from Slovakia and from Italy. Dominant compounds were determined by GC/MS. The results showed high amount of menthol and menthone in tested Slovak peppermint EO. On the other hand, carvone and 1,8-cineole were determinate as dominant compounds in Italian spearmint EO. The antimicrobial activity of the EO was investigated by disc diffusion and broth micro dilution methods. EO was evaluated for their antibacterial activity against 7 microorganisms: Enterobacter cloacae, Salmonella spp., Klebsiella pneumoniae, Escherichia coli, Staphylococcus aureus, Streptococcus pyogenes. The determination results of antibacterial activity by agar disk diffusion method ranged from 7 to 14 mm of the growth inhibition zone. MIC of tested mint EO varied from 0.625 to 2.5 μg/mL. In addition, both EO showed relatively the same antibacterial activity against the selected Gram-negative bacteria. However, there is a variation in the antibacterial activity against Gram-positive bacteria

    Similarity and differences in elderly patients with fixed airflow obstruction by asthma and by chronic obstructive pulmonary disease.

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    SummaryBackgroundEpidemiologic studies have demonstrated that elderly patients with fixed airflow obstruction can be affected by asthma or chronic obstructive pulmonary disease (COPD).MethodsWe studied 49 consecutive elderly outpatients, presenting fixed airflow obstruction, by clinical history (smoking), pulmonary function tests, blood gas analysis, and induced sputum.ResultsThe age was not different in patients with COPD (n=28) and asthma (n=21) (70.2±3.9 years vs. 69.6±3.7 years), also the degree of fixed airflow obstruction was similar (FEV1: 58.3±1.5% vs. 59.0±1.4% of predicted). Patients with asthma had significantly more eosinophils in peripheral blood (0.43±0.05×10−3μL vs. 0.27±0.1×10−3μL, P<0.0001), and in induced sputum (5.0% [(p25th and p75th) 5.0–6.0%] vs. 1.0% [(p25th and p75th) 0.01–1.0%]; P<0.0001), as well as serum ECP (18.6±4.9ng/mL vs. 7.7±4.7ng/mL, P<0.0001) and ECP in the induced sputum (31.6±2.9ng/mL vs. 5.6±4.9ng/mL, P<0.0001). Finally, in induced sputum the eosinophils EG2+ were higher in patients with asthma than in patients with COPD (40.5 [(p25th and p75th) 39.3–44.3] MFI vs. 3.9 [(p25th and p75th) 0–11.4] MFI, P<0.0001). They also had significantly higher diffusing capacity, and a greater reversibility to steroids, after 14-day course of therapy, whereas the reversibility to 400μg of salbutamol was similar.ConclusionDespite similar fixed airflow obstruction, elderly patients with asthma have distinct characteristics compared with patients with COPD
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