Grounded in Experience: Entering Higher-Higher Education as a Pilipino American

The decision to go back to school in pursuit of higher-higher education is an extremely strenuous, anxiety-stricken, self-reflective, and courageous process, especially for those that have been “out of school” for two years or more. Although there is some existing literature on nontraditional students and their journey going to college, there is even less literature on the experiences of returning students that decide to pursue a graduate degree after being academically removed from their undergraduate institution for quite some time. Thus, this paper seeks to examine some of the more specific instances experienced by graduate students, particularly those that returned to academia after working for two years or more. Additionally, this article will further study and highlight this multi-faceted and experiential process: the anxieties, challenges, and overall development of these “returners to the academy.” Lastly, through the lens of the Pilipino American identity, the author will discuss how working within an institution of higher education before attending graduate school has impacted and shaped their personal and professional development as a first-year graduate student, scholar, and practitioner

Enrique de Malacca: Pagsasalin sa Imperyalismong Español

Habang idiniriin ng karamihan sa mga salaysay hinggil sa pagdating ng mga Español sa ating kapuluan ang naging gampanin ni Ferdinand Magellan, Sebastian Elcano, at ng katutubong datu ng Mactan na si Lapulapu, halos wala pang nababanggit tungkol sa tapat na alipin ni Magellan na si Enrique. Bagamat sa kabila ng kaniyang napakahalagang gampanin sa ekspedisyong Magellan-Elcano at malalim na impluwensiya sa kasaysayan ng Pilipinas, halos gatala lamang ang pansing naipagkaloob kay Enrique sa mga matatagpuang salaysay hinggil sa pangyayaring ito. Sa gayon, sa pamamagitan ng matalik na pagbasa sa mga teksto mula sa arkibo at sa mga pamantayang sangguniang pangkasaysayan na nailimbag, nilalayon ng papel na ito hindi lamang ang pagbibigay ng ilang bago at makatotohanang detalye tungkol kay Enrique kundi pati na rin ang paghahabi ng higit na malawak na kontekstong pangkasaysayan ng pinagsasama-samang mga kultural na abot-tanaw, sa pamamagitan na rin ng kaniyang naging gawain ng pagsasalin

Quantifying Isoniazid Levels in Small Hair Samples: A Novel Method for Assessing Adherence during the Treatment of Latent and Active Tuberculosis.

BackgroundTuberculosis (TB) is the leading cause of death from an infectious pathogen worldwide and the most prevalent opportunistic infection in people living with HIV. Isoniazid preventive therapy (IPT) reduces the incidence of active TB and reduces morbidity and mortality in HIV-infected patients independently of antiretroviral therapy. However, treatment of latent or active TB is lengthy and inter-patient variability in pharmacokinetics and adherence common. Current methods of assessing adherence to TB treatment using drug levels in plasma or urine assess short-term exposure and pose logistical challenges. Drug concentrations in hair assess long-term exposure and have demonstrated pharmacodynamic relevance in HIV.MethodsA large hair sample from a patient with active TB was obtained for assay development. Methods to pulverize hair and extract isoniazid were optimized and then the drug detected by liquid chromatography/ tandem mass spectrometry (LC/MS-MS). The method was validated for specificity, accuracy, precision, recovery, linearity and stability to establish the assay's suitability for therapeutic drug monitoring (TDM). Hair samples from patients on directly-observe isoniazid-based latent or active TB therapy from the San Francisco Department of Public Health TB clinic were then tested.ResultsOur LC/MS-MS-based assay detected isoniazid in quantities as low as 0.02ng/mg using 10-25 strands hair. Concentrations in spiked samples demonstrated linearity from 0.05-50ng/mg. Assay precision and accuracy for spiked quality-control samples were high, with an overall recovery rate of 79.5%. In 18 patients with latent or active TB on treatment, isoniazid was detected across a wide linear dynamic range.ConclusionsAn LC-MS/MS-based assay to quantify isoniazid levels in hair with performance characteristics suitable for TDM was developed and validated. Hair concentrations of isoniazid assess long-term exposure and may be useful for monitoring adherence to latent or active TB treatment in the setting of HIV

Promoting adoption of best management practice for forest nurseries through a communication campaign

High quality tree seedlings are critical factors which determine the success of tree plantation projects. To produce high quality seedlings, nursery operators need to apply appropriate nursery management practices. However, tree seedlings produced by nursery operators in the Philippines are often of low quality, due in part to weak organization in the nursery sector and lack of skills in the application of nursery practices among nursery operators. The QSeedling Project or Seedling Enhancement Project funded by the Australian Centre for International Agricultural Research (ACIAR) is being implemented in Leyte and Northern Mindanao to remedy this skills gap. The project includes a communication component to promote widespread adoption of best management practice in forest nurseries. Following the strategic communication approach, information dissemination activities in the project are based on the needs of the target users. Training workshops have been held on producing high quality seedlings. Also, communication materials have been developed for nursery operations, including a training guide, videos, instructional posters on Q-seedling production technologies, and a jingle about Q-seedlings. This paper describes the design and use of these communication materials

Camilo José Cela en Alicante, 1975

Copia digital. Madrid : Ministerio de Educación, Cultura y Deporte. Subdirección General de Coordinación Bibliotecaria, 201

Suspect screening of maternal serum to identify new environmental chemical biomonitoring targets using liquid chromatography-quadrupole time-of-flight mass spectrometry.

The use and advantages of high-resolution mass spectrometry (MS) as a discovery tool for environmental chemical monitoring has been demonstrated for environmental samples but not for biological samples. We developed a method using liquid chromatography-quadrupole time-of-flight MS (LC-QTOF/MS) for discovery of previously unmeasured environmental chemicals in human serum. Using non-targeted data acquisition (full scan MS analysis) we were able to screen for environmental organic acids (EOAs) in 20 serum samples from second trimester pregnant women. We define EOAs as environmental organic compounds with at least one dissociable proton which are utilized in commerce. EOAs include environmental phenols, phthalate metabolites, perfluorinated compounds, phenolic metabolites of polybrominated diphenyl ethers and polychlorinated biphenyls, and acidic pesticides and/or predicted acidic pesticide metabolites. Our validated method used solid phase extraction, reversed-phase chromatography in a C18 column with gradient elution, electrospray ionization in negative polarity and automated tandem MS (MS/MS) data acquisition to maximize true positive rates. We identified "suspect EOAs" using Agilent MassHunter Qualitative Analysis software, to match chemical formulas generated from each sample run with molecular formulas in our unique database of 693 EOAs assembled from multiple environmental literature sources. We found potential matches for 282 (41%) of the EOAs in our database. Sixty-five of these suspect EOAs were detected in at least 75% of the samples; only 19 of these compounds are currently biomonitored in National Health and Nutrition Examination Survey. We confirmed two of three suspect EOAs by LC-QTOF/MS using a targeted method developed through LC-MS/MS, reporting the first confirmation of benzophenone-1 and bisphenol S in pregnant women's sera. Our suspect screening workflow provides an approach to comprehensively scan environmental chemical exposures in humans. This can provide a better source of exposure information to help improve exposure and risk evaluation of industrial chemicals

Tecnologia digital aplicada às restaurações minimamente invasivas

Dissertação para obtenção do grau de Mestre no Instituto Universitário Egas MonizDurante os últimos 30 anos surgiu uma nova abordagem na medicina dentária que promove o desempenho de todos os procedimentos clínicos de forma o mais conservadora possível, a fim de preservar o máximo possível de tecido dentário ou ósseo. Uma das áreas mais envolvida por esta nova tendência é a reabilitação oral. Nesta área da prática clínica diária há 20 ou 30 anos removíamos tecido saudável para assegurar a remoção preventiva e completa da cárie. Durante os últimos anos passamos a tentar remover o mínimo possível de tecido dentário. Esta mudança tem sido possível graças a vários fatores. Por um lado, nos últimos anos temos assistido a grandes avanços nos sistemas adesivos, o que nos permite obter para além de uma retenção mecânica uma retenção química, por outro lado, a contínua evolução tecnológica permite-nos através de imagens digitais planear e realizar tanto preparações como restaurações da forma menos invasiva possível. O sistema que mais tem ajudado nesta mudança é o CAD-CAM (Computer Aided Design/Computer Aided Manufacturing). Através deste sistema e dos seus componentes conseguimos realizar digitalmente todos os processos da odontologia minimamente invasiva, tornando o processo mais fácil e seguro. Graças ainda à tecnologia podemos realizar um diagnóstico precoce das cáries, fazer guias para a preparação dos dentes e desenhar as peças. Isto, juntamente com os avanços acima mencionados relativamente aos sistemas adesivos e materiais, permite-nos realizar um tratamento minimamente invasivo, com boa estética e grande precisão. O objetivo deste trabalho foi avaliar como as novas tecnologias digitais podem influenciar e ajudar na dentisteria minimamente invasiva. Para tal será feita uma pesquisa bibliográfica, assente em artigos disponíveis nas bases de dados Cochrane Library , Medline/Pubmed, Scielo, Google Scholar e B-on, e referentes a artigos dos últimos 10 anos.During the last 30 years a new trend has emerged in dentistry that promotes the performance of all clinical procedures as conservatively as possible in order to preserve as much tooth or bone tissue as possible. One of most affected areas by this new trend is dentistry. In this area of daily clinical practice 20-30 years ago we used to remove healthy tissue to ensure complete removal of caries. During the last few years we have moved on to trying to remove as little tooth tissue as possible. This change was possible thanks to several factors. On the one hand, in the last few years we witnessed great advances in adhesive systems, which allow us to achieve chemical retention. On the other hand, the ongoing technological evolution allows us to design both the preparations and the dental pieces in a minimally invasive way. The system that has helped the most in this change of attitude is CAD-CAM (Computer Aided Design/Computer Aided Manufacturing). Through this system and its components we can carry out all the processes of minimally invasive dentistry digitally, making the process easier and safer. Thanks to this technology, we can carry out an early diagnosis of caries, make preparation guides for the teeth and design the prosthetic pieces. This, together with the aforementioned advances in adhesive systems and materials, allows us to perform a minimally invasive treatment, with good aesthetics and great precision. The aim of this work is to evaluate how new digital technologies can influence and help in minimally invasive dentistry. This evaluation will be made from a bibliographical research, based on articles available in the Cochrane Library, Medline/Pubmed, Scielo, Google Scholar and B-on databases, giving priority to articles referring to the last 10 years.Durante los últimos 30 años ha surgido una nueva tendencia en la odontología que promueve la realización de todos los procedimientos clínicos de la forma más conservadora posible para preservar la mayor cantidad de tejido dental u óseo. Uno de los ámbitos más afectados por esta nueva tendencia es la dentistería. En este ámbito de la práctica clínica diaria, hace 20-30 años eliminábamos el tejido sano para asegurar la eliminación completa de la carie. Durante los últimos años hemos pasado a intentar eliminar el menor tejido dental posible. Este cambio ha sido posible gracias a varios factores. Por un lado, en los últimos años han surgido grandes avances en los sistemas adhesivos, que permiten conseguir una retención química. Por otro lado, la continua evolución tecnológica nos permite diseñar tanto las preparaciones como las piezas dentales de la forma menos invasiva posible. El sistema que más ha ayudado a este cambio de actitud es el CAD-CAM (diseño asistido por ordenador/fabricación asistida por ordenador). A través de este sistema y sus componentes somos capaces de realizar digitalmente todos los procesos de la dentistería mínimamente invasiva, haciendo el proceso más fácil y seguro. Gracias a esta tecnología podemos realizar un diagnóstico precoz de cáries, realizar guías para el tallado de dientes y diseñar las piezas. Esto, junto con los avances ya mencionados en sistemas adhesivos y materiales, nos permite realizar un tratamiento mínimamente invasivo, con buena estética y gran precisión. El objetivo de este trabajo es evaluar cómo las nuevas tecnologías digitales pueden influir y ayudar en la odontología mínimamente invasiva. Esta evaluación se realizará a partir de una investigación bibliográfica, basada en artículos disponibles en las bases de datos Cochrane Library , Medline/Pubmed, Scielo, Google Scholar y B-on, dando prioridad a los artículos publicados en los últimos 10 años