Virological and serological surveillance for type A influenza in the black-legged kittiwake (Rissa tridactyla)

<p>Abstract</p> <p>Background</p> <p>The epidemiology of avian influenza viruses (AIVs) in gulls is only partially known. The role of the world's most numerous gull species, the black-legged kittiwake (<it>Rissa tridactyla</it>), as a potential AIV reservoir species has been unclear. The prevalence of AIV and humoral response against AIV were therefore studied in a colony of apparently healthy black-legged kittiwakes breeding in a nesting cliff in the South West Barents Region of Norway (70°22' N, 31°10' E), in 2008 and 2009.</p> <p>Results</p> <p>AIVs were detected from the oropharynx and cloaca in low amounts, with prevalences of 15% and 5%, in 2008 and 2009, respectively. Direct, partial sequencing of the hemagglutinin (HA) gene revealed that the H4 subtype was present. In 2009, antibodies to influenza A virus were detected in sera from 57 of 80 adult birds. In contrast, none of the three-week-old chicks (n = 18) tested seropositive. Hemagglutination inhibition (HI) assays demonstrated that the adult kittiwakes primarily had antibodies specific to the gull-associated H13 and H16 subtypes, with antibodies to H16 being most common.</p> <p>Conclusions</p> <p>These results support that the highly pelagic black-legged kittiwake is a reservoir of AIV. The serological findings suggest that H16 might be the main AIV subtype in the black-legged kittiwake. Further studies are needed to understand the ecology of AIV in the black-legged kittiwake and in gulls in general.</p

Social representation of hearing aids: cross-cultural study in India, Iran, Portugal, and the United Kingdom

Vinaya Manchaiah,1 Berth Danermark,2 Vinay,3 Tayebeh Ahmadi,4 David Tom&eacute;,5 Rajalakshmi Krishna,6 Per Germundsson7 1Department of Speech and Hearing Sciences, Lamar University, Beaumont, Texas, USA; 2Swedish Institute for Disability Research, &Ouml;rebro University, &Ouml;rebro, Sweden; 3Department of Clinical Medicine, University of Troms&oslash;, Troms&oslash;, Norway; 4Department of Audiology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran; 5Department of Audiology, School of Allied Health Sciences, Polytechnic Institute of Porto, Vila Nova de Gaia, Portugal; 6All India Institute of Speech and Hearing, University of Mysore, Mysore, India; 7The Department of Health and Welfare Studies, Malm&ouml; University, Malm&ouml;, Sweden Background: The current study was aimed at understanding the social representation of hearing aids in India, Iran, Portugal, and the United Kingdom. We also compared these results to explore the cross-cultural differences and similarities among these countries. Methods: The study involved a cross-sectional design, and the data were collected from four different countries using the snowball sampling method. Data were analyzed using a content analysis to identify the most-similar categories of responses reported, a co-occurrences analysis to see which of these categories are reported commonly, and a chi-square analysis to study if there was any association between positive, neutral, and negative connotations among participants in different countries. Results: The current study revealed four different social representations of hearing aids from India, Iran, Portugal, and the United Kingdom, and also a global index. Conclusion: The study results provide very useful insights into how hearing aids are represented in the society. These findings may have important implications for public education and also for manufacturers from the viewpoint of designing and marketing hearing aids in different countries. Keywords: hearing aids, hearing loss, social representation, cross-culture, attitudes, perceptio

Social representation of &ldquo;hearing loss&rdquo;: cross-cultural exploratory study in India, Iran, Portugal, and the UK

Vinaya Manchaiah,1 Berth Danermark,2 Tayebeh Ahmadi,3 David Tom&eacute;,4 Fei Zhao,5 Qiang Li,6 Rajalakshmi Krishna,7 Per Germundsson8 1Department of Speech and Hearing Sciences, Lamar University, Beaumont, TX, USA; 2Swedish Institute for Disability Research, &Ouml;rebro University, &Ouml;rebro, Sweden; 3Department of Audiology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran; 4Department of Audiology, School of Allied Health Sciences, Polytechnic Institute of Porto, Vila Nova de Gaia, Portugal; 5Centre for Speech Language Therapy and Hearing, Cardiff Metropolitan University, Cardiff, UK; 6Department of Social Science and Law, Tianjin University of Technology, Tianjin, People&rsquo;s Republic of China; 7All India Institute of Speech and Hearing, University of Mysore, Mysore, India; 8Department of Health and Welfare Studies, Malm&ouml; University, Malm&ouml;, Sweden Background: Hearing loss is one of the most common chronic conditions in older adults. In&nbsp;audiology literature, several studies have examined the attitudes and behavior of people with hearing loss; however, not much is known about the manner in which society in general views and perceives hearing loss. This exploratory study was aimed at understanding the social representation of hearing loss (among the general public) in the countries of India, Iran, Portugal, and the UK. We also compared these social representations.Materials and methods: The study involved a cross-sectional design, and participants were recruited using the snowball sampling method. A total of 404 people from four countries participated in the study. Data were collected using a free-association task where participants were asked to produce up to five words or phrases that came to mind while thinking about hearing loss. In addition, they were also asked to indicate if each word they presented had positive, neutral, or negative associations in their view. Data were analyzed using various qualitative and quantitative methods.Results: The most frequently occurring categories were: assessment and management; causes of hearing loss; communication difficulties; disability; hearing ability or disability; hearing instruments; negative mental state; the attitudes of others; and sound and acoustics of the environment. Some categories were reported with similar frequency in most countries (eg, causes of hearing loss, communication difficulties, and negative mental state), whereas others differed among countries. Participants in India reported significantly more positive and fewer negative associations when compared to participants from Iran, Portugal, and the UK. However, there was no statistical difference among neutral responses reported among these countries. Also, more differences were noted among these countries than similarities.Conclusion: These findings provide useful insights into the public perception of hearing loss that may prove useful in public education and counseling. Keywords: hearing loss, hearing impairment, social representation, societal attitude, cross-culture, perception of disabilit

The evolutionary dynamics of influenza A virus adaptation to mammalian hosts

Few questions on infectious disease are more important than understanding how and why avian influenza A viruses successfully emerge in mammalian populations, yet little is known about the rate and nature of the virus’ genetic adaptation in new hosts. Here, we measure, for the first time, the genomic rate of adaptive evolution of swine influenza viruses (SwIV) that originated in birds. By using a curated dataset of more than 24 000 human and swine influenza gene sequences, including 41 newly characterized genomes, we reconstructed the adaptive dynamics of three major SwIV lineages (Eurasian, EA; classical swine, CS; triple reassortant, TR). We found that, following the transfer of the EA lineage from birds to swine in the late 1970s, EA virus genes have undergone substantially faster adaptive evolution than those of the CS lineage, which had circulated among swine for decades. Further, the adaptation rates of the EA lineage antigenic haemagglutinin and neuraminidase genes were unexpectedly high and similar to those observed in human influenza A. We show that the successful establishment of avian influenza viruses in swine is associated with raised adaptive evolution across the entire genome for many years after zoonosis, reflecting the contribution of multiple mutations to the coordinated optimization of viral fitness in a new environment. This dynamics is replicated independently in the polymerase genes of the TR lineage, which established in swine following separate transmission from non-swine hosts