Guidelines of the German Medical Association on quality assurance in medical laboratory testing

The Richtlinie der Bundesärztekammer zur Qualitätssicherung laboratoriumsmedizinischer Untersuchungen (Guideline of the German Medical Association on Quality Assurance in Medical Laboratory Examinations - Rili-BAEK) has been completed and published in a revised version in 2014 (Deutsches Ärzteblatt, Jg. 111, Heft 38, 19. September 2014, A1583-A1618).The development of quality management regulations for medical laboratories in Germany already started in 1971 with the publication of the first "Guidelines of the German Medical Association for Statistical Quality Control and Proficiency Testing in the Field of Medical Science" (Richtlinien der Bundesärztekammer zur Durchführung der statistischen Qualitätskontrolle und von Ringversuchen im Bereich der Heilkunde; Deutsches Ärzteblatt 1971, 30, 2228ff.) These guidelines were afterwards modified and developed further in the years 1971, 1988, 2002, and finally in 2008. All these guidelines including the one implemented in 2008 primarily focused on the assessment of process quality through internal and external quality control. Historically, parameters with chemical and biochemical measurands and methods from serum and plasma were addressed first, but over time, the regulations also tackled aspects of necessary technical capabilities and the prerequisites for high quality of analytic results in medical laboratories. In a further step, quality regulations for the analysis of other sample materials such as whole blood, CSF, sperm, and urine were included. Finally most other important areas of laboratory medicine like immune hematology, the whole field of microbiology with direct and indirect detection of pathogens and molecular biology including moleculargenetic and cytogenetic examination were integrated in the currently implied in the guidelines of 2014.The newest version of the Guideline implemented in 2014, which is now mandatory in Germany for all laboratories performing medical laboratory examinations of human specimens, for the first time realizes a total quality management effort for medical laboratories according to current national and international standards including the quality of analytical and structural processes. Therefore, today medical laboratories have to lay open all parts of their analytical processes including the structure of the pre-analytic, analytic and post-analytic phases. Moreover, the Guideline also covers analytical methods for which so far no minimum quality standards have been defined before. This makes the current Guideline of the German Medical Association on Quality Assurance in Medical Laboratory Examinations an important step forward towards a significant improvement of quality in laboratory medicine

Untersuchungen zu oekologischen Problemfaellen der Textilveredlung mit dem Ziel der Eliminierung von Reaktivfarbstoffhydrolysaten, des Wiedereinsatzes von Klotz-Ausruestungsmittelrestflotten sowie zur Entsorgung von Alginat-Druckverdickungen. Bd. 2 Teil 3: Entsorgung von Alginat-Druckverdickungen. Schlussbericht

SIGLEAvailable from TIB Hannover: F94B1317 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekBundesministerium fuer Forschung und Technologie (BMFT), Bonn (Germany)DEGerman

Untersuchungen zu oekologischen Problemfaellen der Textilveredelung mit dem Ziel der Eliminierung von Reaktivfarbstoffhydrolysaten, des Wiedereinsatzes von Klotz-Ausruestungsmittelrestflotten sowie zur Entsorgung von Alginat-Druckverdichtungen. Bd. 1 Teil 1: Eliminierung von Reaktivfarbstoffhydrolysaten. Teil 2: Wiedereinsatz von Klotz-Ausruestungsmittel-Restflotten am Beispiel der Aviviermittel

Available from TIB Hannover: F94B1318 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEBundesministerium fuer Forschung und Technologie (BMFT), Bonn (Germany)DEGerman

SATPOS - Satellitenpositions- und Zeitbestimmung fuer GNSS-2. Bd. 2: Bahnbestimmung bei Intersatellit-Verbindungen Abschlussbericht

SIGLEAvailable from TIB Hannover: F00B1160 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekBundesministerium fuer Bildung, Wissenschaft, Forschung und Technologie, Bonn (Germany); DLR Deutsches Zentrum fuer Luft- und Raumfahrt e.V., Bonn (Germany)DEGerman

Dilepton production in a chemically equilibrating, expanding and hadronizing quark-gluon plasma

Dilpeton production is considered within a complete dynamical framework for thermalized matter assumed to be formed in ultra-relativistic heavy-ion collisions. Our model includes (i) chemical equilibration processes in the initially gluon enriched plasma, and (ii) longitudinal and transversal expansion, and (iii) the hadronization through a mixed phase. Besides the basic electromagnetic quark - antiquark annihilation process we also take into account the QCD Compton like and annihilation processes for calculating the dilepton rate in the deconfined phase, while in the hadronic stage we employ a parametrization of the effective form factor which is based on the complete set of meson decays and reactions. We find that, due to the transverse expansion of the matter, the dilepton yield from the hadron gas is strongly reduced and, therefore, the deconfined matter gives the dominant contribution in case of initial conditions which are expected to be achieved at RHIC. This provides the basis for the M _p_e_r_p_e_n_d_i_c_u_l_a_r _t_o scaling restoration of the dilepton spectra from thermalized matter. (orig.)37 refs.Available from TIB Hannover: RR 1847(95-89) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman

SATPOS - Satellitenpositions- und Zeitbestimmung fuer GNSS-2. Bd. 3: Methoden der Zeitbestimmung Abschlussbericht

SIGLEAvailable from TIB Hannover: F00B1161 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekBundesministerium fuer Bildung, Wissenschaft, Forschung und Technologie, Bonn (Germany); DLR Deutsches Zentrum fuer Luft- und Raumfahrt e.V., Bonn (Germany)DEGerman

Statutory health insurance coverage of noninvasive prenatal testing (NIPT)

In its position paper on statutory health insurance coverage of what is referred to as noninvasive prenatal testing (NIPT), the German Society of Midwifery Science (DGHWi) argues for the tests to be covered by statutory health insurance as this would also ensure the necessary government monitoring and psychosocial and medical advice and support. At the same time, the DGHWi urges for structural measures to be taken to support the statutory health insurance coverage of NIPT. These include, most importantly, comprehensive government support for families of children with special needs. Health insurance coverage of NIPT must also be accompanied by extensive social science research to facilitate a better understanding of this complex technology and its ethical, political and social implications.In ihrem Positionspapier zur Kassenzulassung von sogenannten Nichtinvasiven Pränatalen Tests (NIPTs) spricht sich die Deutsche Gesellschaft für Hebammenwissenschaft (DGHWi) für eine Kostenübernahme der Tests durch die gesetzliche Krankenversicherung aus, da auf diese Weise die notwendige staatliche Steuerung und psychosoziale und medizinische Beratung und Begleitung gewährleistet werden kann. Gleichzeitig drängt die DGHWi auf strukturelle Maßnahmen, die die Kassenzulassung von NIPTs begleiten sollten. Dazu gehört vor allem eine umfassende staatliche Unterstützung von Familien mit Kindern mit besonderen Bedarfen. Die Kassenzulassung von NIPTs sollte umfänglich sozialwissenschaftlich begleitet werden, um diese komplexe Technologie und ihre ethischen, politischen und sozialen Effekte besser zu verstehen