Gold and Silver - but safe?

Gold (Au) and silver (Ag) nanopartucles (NPs) are frequently used in medicine (drug delivery, wound dressings) but also more and more icorporated in every-day life products, such as functional clothing. Therfore, a comprehensive dafety assessment of such particles is essential. Teh aim of this work was the investigation of the suitability of standard DIN-EN-ISO protocolis for cytotoxicity assessment of NPs

Turning Points in the Evolution of Isolated Neutron Stars' Magnetic Fields

During the life of isolated neutron stars (NSs) their magnetic field passes through a variety of evolutionary phases. Depending on its strength and structure and on the physical state of the NS (e.g. cooling, rotation), the field looks qualitatively and quantitatively different after each of these phases. Three of them, the phase of MHD instabilities immediately after NS's birth, the phase of fallback which may take place hours to months after NS's birth, and the phase when strong temperature gradients may drive thermoelectric instabilities, are concentrated in a period lasting from the end of the proto--NS phase until 100, perhaps 1000 years, when the NS has become almost isothermal. The further evolution of the magnetic field proceeds in general inconspicuous since the star is in isolation. However, as soon as the product of Larmor frequency and electron relaxation time, the so-called magnetization parameter, locally and/or temporally considerably exceeds unity, phases, also unstable ones, of dramatic changes of the field structure and magnitude can appear. An overview is given about that field evolution phases, the outcome of which makes a qualitative decision regarding the further evolution of the magnetic field and its host NS.Comment: References updated, typos correcte

Dissociative recombination measurements of HCl+ using an ion storage ring

We have measured dissociative recombination of HCl+ with electrons using a merged beams configuration at the heavy-ion storage ring TSR located at the Max Planck Institute for Nuclear Physics in Heidelberg, Germany. We present the measured absolute merged beams recombination rate coefficient for collision energies from 0 to 4.5 eV. We have also developed a new method for deriving the cross section from the measurements. Our approach does not suffer from approximations made by previously used methods. The cross section was transformed to a plasma rate coefficient for the electron temperature range from T=10 to 5000 K. We show that the previously used HCl+ DR data underestimate the plasma rate coefficient by a factor of 1.5 at T=10 K and overestimate it by a factor of 3.0 at T=300 K. We also find that the new data may partly explain existing discrepancies between observed abundances of chlorine-bearing molecules and their astrochemical models.Comment: Accepted for publication in ApJ (July 7, 2013

The Neutron Stars Census

The paucity of old isolated accreting neutron stars in ROSAT observations is used to derive a lower limit on the mean velocity of neutron stars at birth. The secular evolution of the population is simulated following the paths of a statistical sample of stars for different values of the initial kick velocity, drawn from an isotropic Gaussian distribution with mean velocity $0\leq < V>\leq 550$ ${\rm km s^{-1}}$. The spin--down, induced by dipole losses and the interaction with the ambient medium, is tracked together with the dynamical evolution in the Galactic potential, allowing for the determination of the fraction of stars which are, at present, in each of the four possible stages: Ejector, Propeller, Accretor, and Georotator. Taking from the ROSAT All Sky Survey an upper limit of $\sim 10$ accreting neutron stars within $\sim 140$ pc from the Sun, we infer a lower bound for the mean kick velocity, $\gtrsim 200-300$ ${\rm km s^{-1}},$ corresponding to a velocity dispersion $\sigma_V\gtrsim 125-190$ km s$^{-1}$. The same conclusion is reached for both a constant magnetic field ($B\sim 10^{12}$ G) and a magnetic field decaying exponentially with a timescale $\sim 10^9$ yr. Such high velocities are consistent with those derived from radio pulsar observations. Present results, moreover, constrain the fraction of low velocity stars, which could have escaped pulsar statistics, to less than 1%.Comment: 13 pages, 6 PostScript figures, accepted to Ap

Restrictions on parameters of power-law magnetic field decay for accreting isolated neutron stars

In this short note we discuss the influence of power-law magnetic field decay on the evolution of old accreting isolated neutron stars. We show, that, contrary to exponential field decay (Popov & Prokhorov 2000), no additional restrictions can be made for the parameters of power-law decay from the statistics of isolated neutron star candidates in ROSAT observations. We also briefly discuss the fate of old magnetars with and without field decay, and describe parameters of old accreting magnetars.Comment: 8 pages including 3 PostScript figure

A hierarchical model for aging

We present a one dimensional model for diffusion on a hierarchical tree structure. It is shown that this model exhibits aging phenomena although no disorder is present. The origin of aging in this model is therefore the hierarchical structure of phase space.Comment: 10 pages LaTeX, 4 postscript-figures include

Labeling the human skeleton with 41Ca to assess changes in bone calcium metabolism

Bone research is limited by the methods available for detecting changes in bone metabolism. While dual X-ray absorptiometry is rather insensitive, biochemical markers are subject to significant intra-individual variation. In the study presented here, we evaluated the isotopic labeling of bone using 41Ca, a long-lived radiotracer, as an alternative approach. After successful labeling of the skeleton, changes in the systematics of urinary 41Ca excretion are expected to directly reflect changes in bone Ca metabolism. A minute amount of 41Ca (100nCi) was administered orally to 22 postmenopausal women. Kinetics of tracer excretion were assessed by monitoring changes in urinary 41Ca/40Ca isotope ratios up to 700days post-dosing using accelerator mass spectrometry and resonance ionization mass spectrometry. Isotopic labeling of the skeleton was evaluated by two different approaches: (i) urinary 41Ca data were fitted to an established function consisting of an exponential term and a power law term for each individual; (ii) 41Ca data were analyzed by population pharmacokinetic (NONMEM) analysis to identify a compartmental model that describes urinary 41Ca tracer kinetics. A linear three-compartment model with a central compartment and two sequential peripheral compartments was found to best fit the 41Ca data. Fits based on the use of the combined exponential/power law function describing urinary tracer excretion showed substantially higher deviations between predicted and measured values than fits based on the compartmental modeling approach. By establishing the urinary 41Ca excretion pattern using data points up to day 500 and extrapolating these curves up to day 700, it was found that the calculated 41Ca/40Ca isotope ratios in urine were significantly lower than the observed 41Ca/40Ca isotope ratios for both techniques. Compartmental analysis can overcome this limitation. By identifying relative changes in transfer rates between compartments in response to an intervention, inaccuracies in the underlying model cancel out. Changes in tracer distribution between compartments were modeled based on identified kinetic parameters. While changes in bone formation and resorption can, in principle, be assessed by monitoring urinary 41Ca excretion over the first few weeks post-dosing, assessment of an intervention effect is more reliable ∼150days post-dosing when excreted tracer originates mainly from bon