Signaling, Entanglement, and Quantum Evolution Beyond Cauchy Horizons

Consider a bipartite entangled system half of which falls through the event horizon of an evaporating black hole, while the other half remains coherently accessible to experiments in the exterior region. Beyond complete evaporation, the evolution of the quantum state past the Cauchy horizon cannot remain unitary, raising the questions: How can this evolution be described as a quantum map, and how is causality preserved? What are the possible effects of such nonstandard quantum evolution maps on the behavior of the entangled laboratory partner? More generally, the laws of quantum evolution under extreme conditions in remote regions (not just in evaporating black-hole interiors, but possibly near other naked singularities and regions of extreme spacetime structure) remain untested by observation, and might conceivably be non-unitary or even nonlinear, raising the same questions about the evolution of entangled states. The answers to these questions are subtle, and are linked in unexpected ways to the fundamental laws of quantum mechanics. We show that terrestrial experiments can be designed to probe and constrain exactly how the laws of quantum evolution might be altered, either by black-hole evaporation, or by other extreme processes in remote regions possibly governed by unknown physics.Comment: Combined, revised, and expanded version of quant-ph/0312160 and hep-th/0402060; 13 pages, RevTeX, 2 eps figure

Observation of Amounts of Movement Practice Provided during Stroke Rehabilitation

Objective To investigate how much movement practice occurred during stroke rehabilitation, and what factors might influence doses of practice provided. Design Observational survey of stroke therapy sessions. Setting Seven inpatient and outpatient rehabilitation sites. Participants We observed a convenience sample of 312 physical and occupational therapy sessions for people with stroke. Interventions Not applicable. Main Outcome Measures We recorded numbers of repetitions in specific movement categories and data on potential modifying factors (patient age, side affected, time since stroke, FIM item scores, years of therapist experience). Descriptive statistics were used to characterize amounts of practice. Correlation and regression analyses were used to determine whether potential factors were related to the amount of practice in the 2 important categories of upper extremity functional movements and gait steps. Results Practice of task-specific, functional upper extremity movements occurred in 51% of the sessions that addressed upper limb rehabilitation, and the average number of repetitions/session was 32 (95% confidence interval [CI]=20–44). Practice of gait occurred in 84% of sessions that addressed lower limb rehabilitation and the average number of gait steps/session was 357 (95% CI=296–418). None of the potential factors listed accounted for significant variance in the amount of practice in either of these 2 categories. Conclusions The amount of practice provided during poststroke rehabilitation is small compared with animal models. It is possible that current doses of task-specific practice during rehabilitation are not adequate to drive the neural reorganization needed to promote function poststroke optimally

Electric Propulsion Research and Development at NASA

Electric propulsion (EP) is an important technology for NASA. It has played a major role on three missions, that is Deep Space 1, Dawn and Space Technology 7, and it is planned for use on many more. The ion propulsion system for the ongoing Dawn mission has achieved several notable accomplishments, including providing a total velocity change (delta-V) of over 11 km/s to the spacecraft. As a result of these successes, solar electric propulsion (SEP) is now broadly recognized as an essential technology for both robotic and human exploration. NASA is currently conducting many projects focused on research and development of EP for a variety of applications. All three of NASA's mission directorates that deal directly with space exploration are actively engaged in supporting work in this area. This paper describes these projects in more detail, including the specific engineering activities being conducted at NASA's main centers for EP technology development, namely Glenn Research Center (GRC) and the Jet Propulsion Laboratory (JPL)

The Deglaciation of Maine, USA

The glacial geology of Maine records the northward recession of the Late Wisconsinan Laurentide Ice Sheet, followed by development of a residual ice cap in the Maine-Québec border region due to marine transgression of the St. Lawrence Lowland in Canada. The pattern of deglaciation across southern Maine has been reconstructed from numerous end moraines, deltas and submarine fans deposited during marine transgression of the coastal lowland. Inland from the marine limit, a less-detailed sequence of deglaciation is recorded by striation patterns, meltwater channels, scattered moraines and waterlain deposits that constrain the trend of the ice margin. There is no evidence that the northern Maine ice cap extended as far south-west as the Boundary Mountains and New Hampshire border. Newly-obtained radiocarbon ages from marine and terrestrial ice-proximal environments have improved the chronology of glacial recession in Maine. Many of these ages were obtained by coring late-glacial sediments beneath ponds and lakes. Data from this study show that the state was deglaciated between about 14.5 and 11.0 ka BP (14C years). The coastal moraine belt in southern Maine was deposited by oscillatory ice-margin retreat during the cold pre-Bølling time. Rapid ice recession to northern Maine then occurred between 13 and 11 ka BP, during the warmer Bølling/Allerød chronozones. Radiocarbon-dated pond sediments in western and northern Maine show lithologic evidence of Younger Dryas climatic cooling and persistence of the northern ice cap into Younger Dryas time. A large discrepancy still exists between radiocarbon ages of deglaciation in coastal south-western Maine and the timing of ice retreat indicated by New England varve records in areas to the west. Part of this problem may stem from the uncertainty of reservoir corrections applied to the radiocarbon ages of marine organics

Electric Propulsion Research and Development at NASA

Electric propulsion (EP) is an important technology for NASA. It has played a major role on three missions, that is Deep Space 1, Dawn and Space Technology 7, and it is planned for use on many more. The ion propulsion system for the ongoing Dawn mission has achieved several notable accomplishments, including providing a total velocity change (delta-V) of over 11 km/s to the spacecraft. As a result of these successes, solar electric propulsion (SEP) is now broadly recognized as an essential technology for both robotic and human exploration. NASA is currently conducting many projects focused on research and development of EP for a variety of applications. All three of NASA's mission directorates that deal directly with space exploration are actively engaged in supporting work in this area. This paper describes these projects in more detail, including the specific engineering activities being conducted at NASA's main centers for EP technology development, namely Glenn Research Center (GRC) and the Jet Propulsion Laboratory (JPL)

Assumptions behind grammatical approaches to code-switching: when the blueprint is a red herring

Many of the so-called ‘grammars’ of code-switching are based on various underlying assumptions, e.g. that informal speech can be adequately or appropriately described in terms of ‘‘grammar’’; that deep, rather than surface, structures are involved in code-switching; that one ‘language’ is the ‘base’ or ‘matrix’; and that constraints derived from existing data are universal and predictive. We question these assumptions on several grounds. First, ‘grammar’ is arguably distinct from the processes driving speech production. Second, the role of grammar is mediated by the variable, poly-idiolectal repertoires of bilingual speakers. Third, in many instances of CS the notion of a ‘base’ system is either irrelevant, or fails to explain the facts. Fourth, sociolinguistic factors frequently override ‘grammatical’ factors, as evidence from the same language pairs in different settings has shown. No principles proposed to date account for all the facts, and it seems unlikely that ‘grammar’, as conventionally conceived, can provide definitive answers. We conclude that rather than seeking universal, predictive grammatical rules, research on CS should focus on the variability of bilingual grammars

Spectrum of Mutations in the RPGR Gene That Are Identified in 20% of Families with X-Linked Retinitis Pigmentosa

SummaryThe RPGR (retinitis pigmentosa GTPase regulator) gene for RP3, the most frequent genetic subtype of X-linked retinitis pigmentosa (XLRP), has been shown to be mutated in 10%–15% of European XLRP patients. We have examined the RPGR gene for mutations in a cohort of 80 affected males from apparently unrelated XLRP families, by direct sequencing of the PCR-amplified products from the genomic DNA. Fifteen different putative disease-causing mutations were identified in 17 of the 80 families; these include four nonsense mutations, one missense mutation, six microdeletions, and four intronic-sequence substitutions resulting in splice defects. Most of the mutations were detected in the conserved N-terminal region of the RPGR protein, containing tandem repeats homologous to those present in the RCC-1 protein (a guanine nucleotide-exchange factor for Ran-GTPase). Our results indicate that mutations either in as yet uncharacterized sequences of the RPGR gene or in another gene located in its vicinity may be a more frequent cause of XLRP. The reported studies will be beneficial in establishing genotype-phenotype correlations and should lead to further investigations seeking to understand the mechanism of disease pathogenesis

Spectrum of Mutations in the RPGR Gene That Are Identified in 20% of Families with X-Linked Retinitis Pigmentosa

SummaryThe RPGR (retinitis pigmentosa GTPase regulator) gene for RP3, the most frequent genetic subtype of X-linked retinitis pigmentosa (XLRP), has been shown to be mutated in 10%–15% of European XLRP patients. We have examined the RPGR gene for mutations in a cohort of 80 affected males from apparently unrelated XLRP families, by direct sequencing of the PCR-amplified products from the genomic DNA. Fifteen different putative disease-causing mutations were identified in 17 of the 80 families; these include four nonsense mutations, one missense mutation, six microdeletions, and four intronic-sequence substitutions resulting in splice defects. Most of the mutations were detected in the conserved N-terminal region of the RPGR protein, containing tandem repeats homologous to those present in the RCC-1 protein (a guanine nucleotide-exchange factor for Ran-GTPase). Our results indicate that mutations either in as yet uncharacterized sequences of the RPGR gene or in another gene located in its vicinity may be a more frequent cause of XLRP. The reported studies will be beneficial in establishing genotype-phenotype correlations and should lead to further investigations seeking to understand the mechanism of disease pathogenesis