99 research outputs found
Effects of Financial Statement on the Performance and Growth of SME’s: A Survey of SME’s in Eldoret Langas Area
The study investigates the effects of financial management statements on performance and sustainable growth of SME’s. It engaged a robust OLS econometric model to empirically analyze performance levels alongside the determining variables in this case the profit loss, incomplete records and balance sheet being the main explanatory variables. The findings revealed that performance of SME’s is significantly pegged on decisions based on the statements since, entrepreneurs who registered high profit levels, appreciated the positive and significant contribution of profit loss, incomplete records and the Balance sheet. However, entrepreneurs who registered Average, Low and Breakeven profit levels attributed the negatively significant and reversal effect of financial statement on the undesirable profitability rating. In addition, higher education level seemed to have had an insignificant impact on improving performance level but rather, a neutralization effect of sustaining the prevailing performance level from deteriorating. Hence, without an appropriate adoption of these statements in accordance with the business management ethics, growth and subsequent progress of SME’s in this region remains stifled at the start-up and Life-style development stages prescribed in the enterprise life-cycle model. Keywords: Growth, SME’s, Profitability, Financial Statemen
levels and factors associated with homicide-related deaths in a rural South African population
MSc (Med), Population-Based Field Epidemiology, School of Public Health, Faculty of Health Sciences, University of the WitwatersrandABSTRACT
Background: World Health Organization (WHO) estimates that more than 1.6 million people die every year because of violence and out of these deaths, homicide accounts for almost one third. Ninety percent (90%) of homicide are thought to occur in low and middle income countries. South Africa has one of the most disturbing rates of homicide in the world. These high homicide rates besides resulting in reduced life expectancy also have serious health, social and economic consequences. Aim: The study aimed at quantifying the burden as well as and identifying factors associated with homicide deaths in rural KwaZulu-Natal in South Africa during the period of 2000 to 2008. Objectives: To estimate a 9 year period (2000-2008) homicide incidence rates as well as identify factors associated with homicide-related deaths. Further, the analysis described spatial distribution of homicide-related deaths in a rural South African population. Design: Analytical longitudinal study. Methods: Using data drawn from the Verbal Autopsies (VAs) conducted on all deaths recorded during annual demographic and health surveillance over a 9-year period (2000-2008), Kaplan-Meier (K-M) survival estimates of incidence rates were used to estimate the cumulative probability of death until the end of the period. Estimates were reported by sex and residency. Weibull regression methods were used to investigate factor associated with homicide deaths. Kulldorff spatial scan statistics was used to describe homicide clustering.
Results: With 536 homicide-related deaths, and 814, 715 total Person Years of contribution, the study found an overall incidence rate of 66 (95% CI= (60, 72) per 100, 000 Person Years of
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Observation (PYOs) for the period studied. Death due to firearm was reported the leading cause of mortality (65%). Most deaths occurred over the weekends (43%), followed by Friday (16.2%).The highest homicide incidence rates were recorded in 2001 (90; 95% CI= (71, 111) per 100,000 person years at risk and 2004 (86; 95% CI= (68, 108) per 100,000 person years at risk. Males had a rate that was about six times more than females 115 (95% CI=105,127) per 100,000 PYOs. Age-specific homicide rate were highest among males aged 25-29 years (209.90 per 100,000 PYOs) and females aged 50-54 years (78 per 100,000 PYOs). Resident, age, sex, education, socioeconomic status, and employment independently predicted homicide risk. The study identified two geographical clusters with significantly elevated homicide risk. Conclusion: A significant six fold difference in homicide rate existed between males and females. Sex differential increases with age, with males aged 15-54 years the most likely to be killed, and females aged 55 years and above having the highest homicide rate. Increase in wealth status and level of education increases one‘s risk of homicide. Employment per se was protective from homicide risk. Firearm was the leading cause of mortality. Most deaths occur over the weekend. Two geographical areas with elevated homicide risk were observed. These findings underscore the need to have timely information and strategies for effective violence prevention program to subgroups and areas at risk
Extraction and analysis of tea (Camellia sinensis) seed oil from different clones in Kenya
Kenyan tea (Camellia sinensis) is widely grown for its leaves and is commercialized as black tea. Product diversification and value addition is currently an area of great interest. This study provides data on the physico-chemical properties of Kenyan tea seed oil from selected clones of tea seeds to ascertain its potential applications. Soxhlet extraction using hexane was employed to obtain tea seed oil followed by chemical analysis to assess its properties. Oil yield, iodine value, saponification value, peroxide value, free fatty acids, total polyphenols and antioxidant activity were determined. The oil yields ranged between 16 to 25% w/w. Iodine value was in the range of 86 to 91 g I2/100 g, peroxide value < 3.5 meq O2/kg, saponification value between 182 to 187 mg KOH/g, free fatty acid < 1.5% oleic acid, total polyphenols 0.036 to 0.043 mg/L gallic acid and antioxidant activity of between 14 to 21% 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity. Tea seed oil is stable and can be a potential source of natural antioxidants.Keywords: Tea seed oil, iodine value, saponification value, peroxide value, free fatty acids, total polyphenols, antioxidant activityAfrican Journal of Biotechnology Vol. 12(8), pp. 841-84
An investigation of the transport and dispersion of atmospheric pollutants over Nairobi City
Current rapid deterioration of air quality in most urban can be majorly attributed to ongoing urbanization.
This study simulates air pollutant dispersal over Nairobi city using Hybrid Single Particle Lagrangian Integrated
Trajectory (HYSPLIT) model, considering a case for emission of Total Suspended Particles (TSP) into the
environment. The wind climatology was established using Wind Rose Plot (WRPlot) view. The predominant wind
speed over the city is 4-6 knots and the wind direction is easterly. The forward trajectory of a pollutant released in the city is generally observed to flow to the western side of the city. The pollutant is observed to be dispersed beyond 100 km from the city reducing the concentration of the same in the city. The study recommends for a consultative planning process of the city that factors in the wind characteristics over the city; most industrial activities should be located to the extreme western side of the city to minimize concentration of pollutants over the city. The study
further recommends research to be carried out for a longer period of time to ascertain the quality of rain water during the long rain season. This calls for accurate observation and monitoring of pollution levels over the city and other cities in the country
Assessment of Integrated Disease Surveillance Data Uptake in Community Health Systems within Nairobi County, Kenya
Background: Kenya has since independence struggled to restructure its health system to provide services to its entire population especially in outbreak responses. The last decade has seen the country witness disease outbreaks across the country i.e. Rift Valley fever in June 2018, and Chikungunya and Dengue fever in Mombasa in February 2018. This exposed the country’s lack of preparedness in handling outbreaks at grass root level. Outbreak incidences tend to prevail at community level before a public health action is established, with the situation becoming dire in the lower tier health facilities.Objective: The purpose of the study was to assess the uptake of Integrated Disease Surveillance Response (IDSR) health data and utilisation at community level health systems in the six sub counties within Nairobi County of Kenya.Methodology: The study used cross-sectional descriptive research design on a target population of 1840 community health workers. The study used Yamane formula to calculate the sample size of 371 respondents, selected using stratified sampling and simple random sampling methods. The logistic regression model was used to assess the benefits of Integrated Data Surveillance and Response data in health facilities across Nairobi County. Data was collected using questionnaires, analysis done using Statistical Packages for Social Sciences, and findings presented in form of tables and bar graphs.Results: The study had 315 questionnaires were duly filled and returned, representing 85% response rate. The findings showed that 268(85%) Healthcare Workers lacked training on using disease surveillance data; 236(75%) cited lack of tools for disease surveillance in facilities, while 173(55%)cited lack of timely IDSR data as hindrance to IDSR data uptake. The regression findings showed that training of healthcare workers on IDSR, installation of disease surveillance system tools, and timely collection and dissemination of surveillance data increases the likelihood of IDSR data uptake in community health facilities.Conclusion: The study concluded that IDSR system tools should be installed in community health facilities across the six sub counties in Nairobi County. Training should be emphasised to ensure all health care workers have the required skills to use the IDSR data. There is need to ensure IDSR data is collected and disseminated on time to make it available for interpretation and use by health care workers in their respective facilities
Retrospective cohort study: Clinical presentation and outcomes of pre-eclampsia and eclampsia at Kenyatta National Hospital, Nairobi, Kenya
Pre-eclampsia has two distinct subtypes: early onset pre-eclampsia, which occurs before 34 weeks of gestation, and late onset pre-eclampsia, which occurs after 34 weeks. Few studies examine and compare early and late onset pre-eclampsia in a low- and middle-income country setting. This study’s goal was to establish a profile of patients with hypertensive disorders in pregnancy, especially pre-eclampsia and eclampsia, over a two-year period. At Kenya’s national referral hospital, clinical presentation at admission was examined, as was management of complications, along with maternal and newborn health outcomes in the hospital’s maternity unit, to ascertain any differences in health outcomes for early and late onset pre-eclampsia. This report details the study’s findings, showing that out of the 620 records reviewed, 44 percent of pre-eclamptic and eclamptic women exhibited early onset of pre-eclampsia, while 56 percent had late onset. Early onset of pre-eclampsia was associated with greater disease severity as well as adverse maternal and perinatal outcomes. Early detection, continuous monitoring, identification of risk factors, and prompt referral are critical in mitigating the serious consequences of pre-eclampsia and eclampsia
Neonatal nasogastric tube feeding in a low-resource African setting - using ergonomics methods to explore quality and safety issues in task sharing.
BACKGROUND: Sharing tasks with lower cadre workers may help ease the burden of work on the constrained nursing workforce in low- and middle-income countries but the quality and safety issues associated with shifting tasks are rarely critically evaluated. This research explored this gap using a Human Factors and Ergonomics (HFE) method as a novel approach to address this gap and inform task sharing policies in neonatal care settings in Kenya. METHODS: We used Hierarchical Task Analysis (HTA) and the Systematic Human Error Reduction and Prediction Approach (SHERPA) to analyse and identify the nature and significance of potential errors of nasogastric tube (NGT) feeding in a neonatal setting and to gain a preliminary understanding of informal task sharing. RESULTS: A total of 47 end tasks were identified from the HTA. Sharing, supervision and risk levels of these tasks reported by subject matter experts (SMEs) varied broadly. More than half of the tasks (58.3%) were shared with mothers, of these, 31.7% (13/41) and 68.3% were assigned a medium and low level of risk by the majority (≥4) of SMEs respectively. Few tasks were reported as 'often missed' by the majority of SMEs. SHERPA analysis suggested omission was the commonest type of error, however, due to the low risk nature, omission would potentially result in minor consequences. Training and provision of checklists for NGT feeding were the key approaches for remedying most errors. By extension these strategies could support safer task shifting. CONCLUSION: Inclusion of mothers and casual workers in care provided to sick infants is reported by SMEs in the Kenyan neonatal settings. Ergonomics methods proved useful in working with Kenyan SMEs to identify possible errors and the training and supervision needs for safer task-sharing
The Plasmodium falciparum Rh5 invasion protein complex reveals an excess of rare variant mutations.
BACKGROUND: The invasion of the red blood cells by Plasmodium falciparum merozoites involves the interplay of several proteins that are also targets for vaccine development. The proteins PfRh5-PfRipr-PfCyRPA-Pfp113 assemble into a complex at the apical end of the merozoite and are together essential for erythrocyte invasion. They have also been shown to induce neutralizing antibodies and appear to be less polymorphic than other invasion-associated proteins, making them high priority blood-stage vaccine candidates. Using available whole genome sequencing data (WGS) and new capillary sequencing data (CS), this study describes the genetic polymorphism in the Rh5 complex in P. falciparum isolates obtained from Kilifi, Kenya. METHODS: 162 samples collected in 2013 and 2014 were genotyped by capillary sequencing (CS) and re-analysed WGS from 68 culture-adapted P. falciparum samples obtained from a drug trial conducted from 2005 to 2007. The frequency of polymorphisms in the merozoite invasion proteins, PfRh5, PfRipr, PfCyRPA and PfP113 were examined and where possible polymorphisms co-occurring in the same isolates. RESULTS: From a total 70 variants, including 2 indels, 19 SNPs [27.1%] were identified by both CS and WGS, while an additional 15 [21.4%] and 36 [51.4%] SNPs were identified only by either CS or WGS, respectively. All the SNPs identified by CS were non-synonymous, whereas WGS identified 8 synonymous and 47 non-synonymous SNPs. CS identified indels in repeat regions in the p113 gene in codons 275 and 859 that were not identified in the WGS data. The minor allele frequencies of the SNPs ranged between 0.7 and 34.9% for WGS and 1.1-29.6% for CS. Collectively, 12 high frequency SNPs (> 5%) were identified: four in Rh5 codon 147, 148, 203 and 429, two in p113 at codons 7 and 267 and six in Ripr codons 190, 259, 524, 985, 1003 and 1039. CONCLUSION: This study reveals that the majority of the polymorphisms are rare variants and confirms a low level of genetic polymorphisms in all proteins within the Rh5 complex
Cost-benefit analysis of substituting bamboo for tobacco : a case study of smallholder tobacco farmers in South Nyanza, Kenya
This study applied the framework of cost benefit analysis to both tobacco and bamboo. Results showed that bamboo farming is financially and economically beneficial to tobacco farmers. Bamboo is amenable to intercropping in the first two years and restores degraded areas from tobacco growing. There are cumulative incremental benefits. However, tobacco has been considered more profitable because it has a guaranteed market where farmers receive complete reimbursement for produce at once. This study examined bamboo as a crop substitute for tobacco in four districts in South Nyanza, Kenya
Agronomic management controls microbial populations in soils of western Kenya
The provision of food requirements for current and future generations can be guaranteed through agricultural intensification options that safeguard the production resource base. Over the years, the debate on sustainable agricultural intensification has not been matched with due regard to how the intensification options influence the functions and balance of soil organisms and soil biology in general. Soil mesofauna and microorganisms have received very little attention so far. In sub-Saharan Africa (SSA) especially, there is very little knowledge and documentation of soil micro-organismal functioning and how these affect and are affected by the abiotic environment (soil physical and chemical properties, and climatic conditions), as well as agricultural management and intensification. Therefore, there is need to evaluate how measures to restore soil fertility and improve its productivity influence not only crop productivity and soil physical and chemical changes, but also soil biology, i.e. the diversity of macro-, meso- and micro-fauna and flora.
In addition, the impact of ‘sustainable’ intensification on the evolution of greenhouse gas (GHG) emissions and related climate footprint remains to be assessed in a comprehensive manner.
Key intensification options currently under promotion by practitioners include conservation agriculture and various integrated soil fertility management (ISFM) options. Minimum soil disturbance, a minimum soil cover of at least 30% throughout the season and crop rotation/intercropping, all of which are principles of conservation agriculture (CA), have been shown to not only introduce shifts in microbial populations but also improve soil structure (Kihara et al., 2012) and enhance carbon sequestration in the top soil. On the other hand, increased aggregation in CA provides anaerobic microsites suitable for micro-organisms that contribute to nitrogen (N) losses through denitrification, and the release of nitrous oxide (N2O); a potent GHG. How such losses are influenced by nutrient inputs, such as through application of mineral fertilizer or biological N fixation, remains largely un-assessed in SSA.
The use of chemical fertilizers, one way of increasing crop productivity in SSA, can have variable effects on microbial biomass and activity (Wardle, 1992; Treseder, 2008). For instance, increased amounts of readily available forms of key inorganic mineral nutrients, e.g. N and P, can decrease population and diversity of various microbial functional groups associated with nutrient uptake (e.g. arbuscular mycorrhizae fungi) and nitrogen fixation (e.g. rhizobium) (Azcón-Aguilar and Bago, 1994; Smith and Read, 1997). On the other hand, fertilizer use increases plant biomass production which, when returned to the soil, promotes microbial proliferation and diversity (Álvarez, 2005). The effects of fertilizer use, either alone or in combination of organic resources, on soil micro-organisms need, therefore, to be evaluated in order to guide sound soil management practices
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