64 research outputs found

    Manipulative imputations in a distributed decision support setting:the effects of information asymmetry and information aggregation complexity

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    According to earlier research, distributed decision support structures are susceptible to deception. We complement the existing works by analyzing group members' attempts to manipulate group decisions supported by distributed communications. Experimentally, we manipulated two systemic features of a distributed support structure: the members' information asymmetry and decision rule complexity. Both of these features refer to structural properties of aggregated information exchange. We confirmed several hypothesized effects: An increase in the information asymmetry in the aggregation of information increases the incidence of the members' manipulative tendency. It also increases the effectiveness of the members' manipulative imputations. However, the complexity of a decision rule negatively moderates both of these effects. We point out the theoretical relevance and managerial implications of our findings. We conclude that managing team members' information asymmetry and complexity of issues under their practical consideration may result in valuable disclosures

    Topological insights in polynuclear Ni/Na coordination clusters derived from a schiff base ligand

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    This article presents the syntheses, crystal structures, topological features and magnetic properties of two NiII/NaI coordination clusters (CCs) formulated [NiII3Na(L1)3(HL1 (MeOH)2] (1) and [NiII6Na(L1)5(CO3)(MeO (MeOH)3(H2O)3]·4(MeOH) 2(H2O) [2 4(MeOH) 2(H2O)] where H2L1 is the semi rigid Schiff base ligand (E)-2-(2-hydroxy-3 methoxybenzylideneamino)-phenol). Compound 1 possesses a rare NiII3NaI cubane (3M4-1) topology and compound 2 is the first example in polynuclear Ni/Na chemistry that exhibits a 2,3,4M7-1 topology

    Modern coordination chemistry

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    Transcriptional changes are regulated by metabolic pathway dynamics but decoupled from protein levels

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    Transcription is necessary for the synthesis of new proteins, often leading to the assumption that changes in transcript levels lead to changes in protein levels which directly impact a cell’s phenotype. Using a synchronized biological rhythm, we show that despite genome-wide partitioning of transcription, transcripts and translation levels into two phase-shifted expression clusters related to metabolism, detectable protein levels remain constant over time. This disconnect between cycling translation and constant protein levels can be explained by slow protein turnover rates, with overall protein levels maintained by low level pulses of new protein synthesis. Instead, rhythmic post-translational regulation of the activities of different proteins, influenced by the metabolic state of the cells, appears to be key to coordinating the physiology of the biological rhythm with cycling transcription. Thus, transcriptional and translational cycling reflects, rather than drives, metabolic and biosynthetic changes during biological rhythms. We propose that transcriptional changes are often the consequence, rather than the cause, of changes in cellular physiology and that caution is needed when inferring the activity of biological processes from transcript data
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