4,359 research outputs found
Letter sent from George E. West to Illinois Council of members of National Association of Certified Public Accountants, October 31, 1922
In concluding our effort to improve conditions in the National Association of Certified Public Accountants, we are under obligation to give you this report of the proceedings of the annual meeting held in Washington last June, and to declare the facts concerning certain published statements of President Hutchison. This report has been delayed considerably by our unsuccessful efforts to procure a certified copy of the record of the proceedings, which President Hutchison is arbitrarily withholding
Causes of cull apples
Cover title."This is a revised edition of Bulletin 319, 'Factors causing cull apples in Missouri'"--P. [3]
The holonomy of the supercovariant connection and Killing spinors
We show that the holonomy of the supercovariant connection for M-theory
backgrounds with Killing spinors reduces to a subgroup of SL(32-N,\bR)\st
(\oplus^N \bR^{32-N}). We use this to give the necessary and sufficient
conditions for a background to admit Killing spinors. We show that there is
no topological obstruction for the existence of up to 22 Killing spinors in
eleven-dimensional spacetime. We investigate the symmetry superalgebras of
supersymmetric backgrounds and find that their structure constants are
determined by an antisymmetric matrix. The Lie subalgebra of bosonic generators
is related to a real form of a symplectic group. We show that there is a
one-one correspondence between certain bases of the Cartan subalgebra of
sl(32, \bR) and supersymmetric planar probe M-brane configurations. A
supersymmetric probe configuration can involve up to 31 linearly independent
planar branes and preserves one supersymmetry. The space of supersymmetric
planar probe M-brane configurations is preserved by an SO(32,\bR) subgroup of
SL(32, \bR).Comment: 27 pages, a key reference was added. v3: minor change
Fractional Generalization of Kac Integral
Generalization of the Kac integral and Kac method for paths measure based on
the Levy distribution has been used to derive fractional diffusion equation.
Application to nonlinear fractional Ginzburg-Landau equation is discussed.Comment: 16 pages, LaTe
Dynamics with Low-Level Fractionality
The notion of fractional dynamics is related to equations of motion with one
or a few terms with derivatives of a fractional order. This type of equation
appears in the description of chaotic dynamics, wave propagation in fractal
media, and field theory. For the fractional linear oscillator the physical
meaning of the derivative of order is dissipation. In systems with
many spacially coupled elements (oscillators) the fractional derivative, along
the space coordinate, corresponds to a long range interaction. We discuss a
method of constructing a solution using an expansion in
with small and positive integer . The method is applied to the
fractional linear and nonlinear oscillators and to fractional Ginzburg-Landau
or parabolic equations.Comment: LaTeX, 24 pages, to be published in Physica
The evolution of ultraviolet emission lines from the circumstellar material surrounding SN 1987A
The presence of narrow high-temperature emission lines from nitrogen-rich gas
close to SN 1987A has been the principal observational constraint on the evolu-
tionary status of the supernova's progenitor. A new analysis of the complete
five-year set of low and high resolution IUE ultraviolet spectra of SN 1987A
(1987.2--1992.3) provide fluxes for the N V 1240, N IV] 1486, He II 1640, OIII]
1665, NIII] 1751, and CIII] 1908 lines with significantly reduced random and
systematic errors and reveals significant short-term fluctuations in the light
curves. The N V, N IV] and N III] lines turn on sequentially over 15 to 20 days
and show a progression from high to low ionization potential, implying an ioni-
zation gradient in the emitting region. The line emission turns on suddenly at
83+/-4 days after the explosion, as defined by N IV]. The N III] line reaches
peak luminosity at 399+/-15 days. A ring radius of (6.24+/-0.20)E{17} cm and
inclination of 41.0+/-3.9 is derived from these times, assuming a circular
ring. The probable role of resonant scattering in the N V light curve
introduces systematic errors that leads us to exclude this line from the timing
analysis. A new nebular analysis yields improved CNO abundance ratios
N/C=6.1+/-1.1 and N/O=1.7+/-0.5, confirming the nitrogen enrichment found in
our previous paper. From the late-time behavior of the light curves we find
that the emission origi- nates from progressively lower density gas. We
estimate the emitting mass near maximum (roughly 400 days) to be roughly
4.7E{-2} solar masses, assuming a filling factor of unity and an electron
density of 2.6E4 cm^{-3}. These results are discussed in the context of current
models for the emission and hydrodynamics of the ring.Comment: 38 pages, AASTeX v.4.0, 13 Postscript figures; ApJ, in pres
Thrombolytic removal of intraventricular haemorrhage in treatment of severe stroke: results of the randomised, multicentre, multiregion, placebo-controlled CLEAR III trial
Background:
Intraventricular haemorrhage is a subtype of intracerebral haemorrhage, with 50% mortality and serious disability for survivors. We aimed to test whether attempting to remove intraventricular haemorrhage with alteplase versus saline irrigation improved functional outcome.
Methods:
In this randomised, double-blinded, placebo-controlled, multiregional trial (CLEAR III), participants with a routinely placed extraventricular drain, in the intensive care unit with stable, non-traumatic intracerebral haemorrhage volume less than 30 mL, intraventricular haemorrhage obstructing the 3rd or 4th ventricles, and no underlying pathology were adaptively randomly assigned (1:1), via a web-based system to receive up to 12 doses, 8 h apart of 1 mg of alteplase or 0·9% saline via the extraventricular drain. The treating physician, clinical research staff, and participants were masked to treatment assignment. CT scans were obtained every 24 h throughout dosing. The primary efficacy outcome was good functional outcome, defined as a modified Rankin Scale score (mRS) of 3 or less at 180 days per central adjudication by blinded evaluators. This study is registered with ClinicalTrials.gov, NCT00784134.
Findings:
Between Sept 18, 2009, and Jan 13, 2015, 500 patients were randomised: 249 to the alteplase group and 251 to the saline group. 180-day follow-up data were available for analysis from 246 of 249 participants in the alteplase group and 245 of 251 participants in the placebo group. The primary efficacy outcome was similar in each group (good outcome in alteplase group 48% vs saline 45%; risk ratio [RR] 1·06 [95% CI 0·88–1·28; p=0·554]). A difference of 3·5% (RR 1·08 [95% CI 0·90–1·29], p=0·420) was found after adjustment for intraventricular haemorrhage size and thalamic intracerebral haemorrhage. At 180 days, the treatment group had lower case fatality (46 [18%] vs saline 73 [29%], hazard ratio 0·60 [95% CI 0·41–0·86], p=0·006), but a greater proportion with mRS 5 (42 [17%] vs 21 [9%]; RR 1·99 [95% CI 1·22–3·26], p=0·007). Ventriculitis (17 [7%] alteplase vs 31 [12%] saline; RR 0·55 [95% CI 0·31–0·97], p=0·048) and serious adverse events (114 [46%] alteplase vs 151 [60%] saline; RR 0·76 [95% CI 0·64–0·90], p=0·002) were less frequent with alteplase treatment. Symptomatic bleeding (six [2%] in the alteplase group vs five [2%] in the saline group; RR 1·21 [95% CI 0·37–3·91], p=0·771) was similar.
Interpretation:
In patients with intraventricular haemorrhage and a routine extraventricular drain, irrigation with alteplase did not substantially improve functional outcomes at the mRS 3 cutoff compared with irrigation with saline. Protocol-based use of alteplase with extraventricular drain seems safe. Future investigation is needed to determine whether a greater frequency of complete intraventricular haemorrhage removal via alteplase produces gains in functional status
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