6,692 research outputs found
Design, Simulation and Development of Software Modules for the Control of Concrete Elements Production Plant
A multi-color fast-switching microfluidic droplet dye laser
We describe a multi-color microfluidic dye laser operating in whispering gallery mode based on a train of alternating droplets containing solutions of different dyes; this laser is capable of switching the wavelength of its emission between 580 nm and 680 nm at frequencies up to 3.6 kHz -— the fastest among all dye lasers reported; it has potential applications in on-chip spectroscopy and flow cytometry
Microwave Continuum Emission and Dense Gas Tracers in NGC 3627: Combining Jansky VLA and ALMA Observations
We present Karl G. Jansky Very Large Array (VLA) Ka band (33 GHz) and Atacama
Large Millimeter Array (ALMA) Band 3 (94.5 GHz) continuum images covering the
nucleus and two extranuclear star-forming regions within the nearby galaxy NGC
3627 (M 66), observed as part of the Star Formation in Radio Survey (SFRS).
Both images achieve an angular resolution of 2\arcsec, allowing us to
map the radio spectral indices and estimate thermal radio fractions at a linear
resolution of 90 pc at the distance of NGC 3627. The thermal fraction
at 33 GHz reaches unity at and around the peaks of each HII region; we
additionally observed the spectral index between 33 and 94.5 GHz to become both
increasingly negative and positive away from the peaks of the HII regions,
indicating an increase of non-thermal extended emission from diffusing
cosmic-ray electrons and the possible presence of cold dust, respectively.
While the ALMA observations were optimized for collecting continuum data, they
also detected line emission from the transitions of HCN and
HCO. The peaks of dense molecular gas traced by these two spectral lines
are spatially offset from the peaks of the 33 and 94.5 GHz continuum emission
for the case of the extranuclear star-forming regions, indicating that our data
reach an angular resolution at which one can spatially distinguish sites of
recent star formation from the sites of future star formation. Finally, we find
trends of decreasing dense gas fraction and velocity dispersion with increasing
star formation efficiency among the three regions observed, indicating that the
dynamical state of the dense gas, rather than its abundance, plays a more
significant role in the star formation process.Comment: 9 pages, 5 figures, accepted for publication in Ap
Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory.
Modeling studies suggest that clustered structural plasticity of dendritic spines is an efficient mechanism of information storage in cortical circuits. However, why new clustered spines occur in specific locations and how their formation relates to learning and memory (L&M) remain unclear. Using in vivo two-photon microscopy, we track spine dynamics in retrosplenial cortex before, during, and after two forms of episodic-like learning and find that spine turnover before learning predicts future L&M performance, as well as the localization and rates of spine clustering. Consistent with the idea that these measures are causally related, a genetic manipulation that enhances spine turnover also enhances both L&M and spine clustering. Biophysically inspired modeling suggests turnover increases clustering, network sparsity, and memory capacity. These results support a hotspot model where spine turnover is the driver for localization of clustered spine formation, which serves to modulate network function, thus influencing storage capacity and L&M
Hyperbaric Oxygen Therapy as a Sole Agent Is Not Immunosuppressant in a Highly Immunogenic Mouse Model
Background. Hyperbaric oxygen (HBO) therapy, which is used for many conditions, may also have immunosuppressive effects and could be used for prevention or treatment of graft-versus-host disease (GvHD). If HBO is immunosuppressant, then we hypothesize that HBO therapy will delay the T-cell mediated skin graft rejection. Methods. C57/BL6 black-coated (H2B) mice received skin graft from CBA (H2D) white-coated mice. Mice were treated with either 19 session of 240 kpa oxygen or 29 session of 300 kpa oxygen, for 90 minutes. Mice were housed either 4 per cage or separately, to prevent friction and mechanical factors that may affect graft survival. Skin grafts were assessed daily. Results. There was no difference in length of graft survival between mice that received either regimens of HBO therapy and mice that did not receive HBO therapy. Conclusions. HBO therapy, as a sole agent, did not delay skin graft rejection in a highly immunogenic mouse model
Stereocontrolled Total Synthesis of Bastimolide B Using Iterative Homologation of Boronic Esters
[Image: see text] Bastimolide B is a polyhydroxy macrolide isolated from marine cyanobacteria displaying antimalarial activity. It features a dense array of hydroxylated stereogenic centers with 1,5-relationships along a hydrocarbon chain. These 1,5-polyols represent a particularly challenging motif for synthesis, as the remote position of the stereocenters hampers stereocontrol. Herein, we present a strategy for 1,5-polyol stereocontrolled synthesis based on iterative boronic ester homologation with enantiopure magnesium carbenoids. By merging boronic ester homologation and transition-metal-catalyzed alkene hydroboration and diboration, the acyclic backbone of bastimolide B was rapidly assembled from readily available building blocks with full control over the remote stereocenters, enabling the total synthesis to be completed in 16 steps (LLS)
Hadronic Resonances from Lattice QCD
The determination of the pattern of hadronic resonances as predicted by
Quantum Chromodynamics requires the use of non-perturbative techniques. Lattice
QCD has emerged as the dominant tool for such calculations, and has produced
many QCD predictions which can be directly compared to experiment. The concepts
underlying lattice QCD are outlined, methods for calculating excited states are
discussed, and results from an exploratory Nucleon and Delta baryon spectrum
study are presented.Comment: 8 pages, VII Latin American Symposium on Nuclear Physics and
Application
Results and Frontiers in Lattice Baryon Spectroscopy
The Lattice Hadron Physics Collaboration (LHPC) baryon spectroscopy effort is
reviewed. To date the LHPC has performed exploratory Lattice QCD calculations
of the low-lying spectrum of Nucleon and Delta baryons. These calculations
demonstrate the effectiveness of our method by obtaining the masses of an
unprecedented number of excited states with definite quantum numbers. Future
work of the project is outlined.Comment: To appear in the proceedings for the VII Latin American Symposium of
Nuclear Physics and Application
Complex Radio Spectral Energy Distributions in Luminous and Ultraluminous Infrared Galaxies
We use the Expanded Very Large Array to image radio continuum emission from
local luminous and ultraluminous infrared galaxies (LIRGs and ULIRGs) in 1 GHz
windows centered at 4.7, 7.2, 29, and 36 GHz. This allows us to probe the
integrated radio spectral energy distribution (SED) of the most energetic
galaxies in the local universe. The 4-8 GHz flux densities agree well with
previous measurements. They yield spectral indices \alpha \approx -0.67 (where
F_\nu \propto \nu^\alpha) with \pm 0.15 (1\sigma) scatter, typical of
nonthermal (synchrotron) emission from star-forming galaxies. The contrast of
our 4-8 GHz data with literature 1.5 and 8.4 GHz flux densities gives further
evidence for curvature of the radio SED of U/LIRGs. The SED appears flatter
near \sim 1 GHz than near \sim 6 GHz, suggesting significant optical depth
effects at the lower frequencies. The high frequency (28-37 GHz) flux densities
are low compared to extrapolations from the 4-8 GHz data. We confirm and extend
to higher frequency a previously observed deficit of high frequency radio
emission for luminous starburst galaxies.Comment: 7 pages, 3 figures, 1 table, accepted for publication in the EVLA
Special Issue of ApJ Letter
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