1,009 research outputs found

    The architecture and fine structure of gill filaments in the brown mussel, Perna perna

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    For many years, bivalve molluscs have played a useful role in determining the impact of pollution on marine organisms. In the northern hemisphere, ecologists from countries subscribing to the International Mussel Watch have used toxin-mediated changes in the organs of Mytilus edulis, especially in the morphology of gill filaments, to indicate the biotoxicity of marine effluent. M. edulis is not indigenous to South African waters. For us to adopt a similar approach on the South African east coast, it is necessary to catalogue both the normal appearance and toxin-mediated changes in our local brown mussel Perna perna. In this study, the gill filaments from five healthy, adult brown mussels were studied by light and transmission electron microscopy. Special attention was paid to filament architecture, ennervation of filaments, number and type of cells populating filament epithelia and variations in epithelial cell morphology and cilia ultrastructure. Filament shape was maintained by thickened chi-tln and strategically placed smooth myocytes. The epithelium was populated with eight morphologically distinctive non-secretory, mucus secreting or sensory cell types in various stages of differentiation. Unmyelinated nerves were situated beneath six cell types. Significant differences in filament architecture and epithelial cell morphology were found between M. edulis and P. perna. It is hoped that this comprehensive description of normal P. perna gill filaments will provide a morphological baseline for local pollution impact studies

    Helium mixtures in nanotube bundles

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    An analogue to Raoult's law is determined for the case of a 3He-4He mixture adsorbed in the interstitial channels of a bundle of carbon nanotubes. Unlike the case of He mixtures in other environments, the ratio of the partial pressures of the coexisting vapor is found to be a simple function of the ratio of concentrations within the nanotube bundle.Comment: 3 pages, no figures, submitted to Phys. Rev. Let

    Site characterisation : astronomical seeing from a turbulence-resolving model

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    A Lunar Laser Ranging (LLR) system is to form part of geodetic instrumentation to be located at a new fundamental space geodetic observatory for South Africa. For optimal efficiency, LLR requires optical resolution or so-called astronomical seeing conditions of ~1 arc-second in order to deliver usable ranging data. Site characterisation should include a description of astronomical seeing for various locations on-site and overall atmospheric conditions. Atmospheric turbulence degrades astronomical seeing. In-situ methods of determining astronomical seeing are difficult, time-consuming and costly. We propose the use of a turbulence-resolving model to determine and predict astronomical seeing at a site. Large Eddy Simulation NERSC (Nansen Environmental and Remote Sensing Centre) Improved Code (LESNIC) is a turbulence-resolving simulation code which models atmospheric turbulence. It has been used to compile a database of turbulence-resolving simulations, referred to as DATABASE64. This database consists of a collection of LESNIC runs for a stably stratified planetary boundary layer (SBL) over a homogeneous aerodynamically rough surface. Results from DATABASE64 for the nocturnal boundary layer are employed to render profiles of the vertical distribution of optical turbulence (CN 2 profiles). Seeing parameter values are also obtained by making use of DATABASE64 results. The CN 2 profiles and seeing parameter values obtained from DATABASE64 results are compared with general observational results that have been published in the literature. The values obtained are consistent with results from field campaigns as reported. Turbulence-resolving models, such as LESNIC, show potential for delivering and predicting profiles and parameters to characterise astronomical seeing, which are essential prerequisites for establishing an LLR system at the most suitable site and most suitable on-site location. A two-pronged approach is envisaged – in addition to modelling, quantitative seeing measurements obtained with an on-site seeing monitor will be used to verify and calibrate results produced by the LESNIC model.http://www.gssa.org.za/index.php?module=htmlpages&func=display&pid=5nf201

    Using Genetic Variation to Explore the Causal Effect of Maternal Pregnancy Adiposity on Future Offspring Adiposity: A Mendelian Randomisation Study

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    Background: It has been suggested that greater maternal adiposity during pregnancy affects lifelong risk of offspring fatness via intrauterine mechanisms. Our aim was to use Mendelian randomisation (MR) to investigate the causal effect of intrauterine exposure to greater maternal body mass index (BMI) on offspring BMI and fat mass from childhood to early adulthood. Methods and Findings: We used maternal genetic variants as instrumental variables (IVs) to test the causal effect of maternal BMI in pregnancy on offspring fatness (BMI and dual-energy X-ray absorptiometry [DXA] determined fat mass index [FMI]) in a MR approach. This was investigated, with repeat measurements, from ages 7 to 18 in the Avon Longitudinal Study of Parents and Children (ALSPAC; n = 2,521 to 3,720 for different ages). We then sought to replicate findings with results for BMI at age 6 in Generation R (n = 2,337 for replication sample; n = 6,057 for total pooled sample). In confounder-adjusted multivariable regression in ALSPAC, a 1 standard deviation (SD, equivalent of 3.7 kg/m2) increase in maternal BMI was associated with a 0.25 SD (95% CI 0.21–0.29) increase in offspring BMI at age 7, with similar results at later ages and when FMI was used as the outcome. A weighted genetic risk score was generated from 32 genetic variants robus

    Nonvalidated home blood pressure devices dominate the online marketplace in Australia: major implications for cardiovascular risk management

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    Self-home blood pressure (BP) monitoring is recommended to guide clinical decisions on hypertension and is used worldwide for cardiovascular risk management. People usually make their own decisions when purchasing BP devices, which can be made online. If patients purchase nonvalidated devices (those not proven accurate according to internationally accepted standards), hypertension management may be based on inaccurate readings resulting in under- or over-diagnosis or treatment. This study aimed to evaluate the number, type, percentage validated, and cost of home BP devices available online. A search of online businesses selling devices for home BP monitoring was conducted. Multinational companies make worldwide deliveries, so searches were restricted to BP devices available for one nation (Australia) as an example of device availability through the global online marketplace. Validation status of BP devices was determined according to established protocols. Fifty nine online businesses, selling 972 unique BP devices were identified. These included 278 upper-arm cuff devices (18.3% validated), 162 wrist-cuff devices (8.0% validated), and 532 wrist-band wearables (0% validated). Most BP devices (92.4%) were stocked by international e-commerce businesses (eg, eBay, Amazon), but only 5.5% were validated. Validated cuff BP devices were more expensive than nonvalidated devices: median (interquartile range) of 101.1 (75.0–151.5) versus 67.4 (30.4–112.8) Australian Dollars. Nonvalidated BP devices dominate the online marketplace and are sold at lower cost than validated ones, which is a major barrier to accurate home BP monitoring and cardiovascular risk management. Before purchasing a BP device, people should check it has been validated at https://www.stridebp.org

    Pulsar kicks from a dark-matter sterile neutrino

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    We show that a sterile neutrino with mass in the 1-20 keV range and a small mixing with the electron neutrino can simultaneously explain the origin of the pulsar motions and the dark matter in the universe. An asymmetric neutrino emission from a hot nascent neutron star can be the explanation of the observed pulsar velocities. In addition to the pulsar kick mechanism based on resonant neutrino transitions, we point out a new possibility: an asymmetric off-resonant emission of sterile neutrinos. The two cases correspond to different values of the masses and mixing angles. In both cases we identify the ranges of parameters consistent with the pulsar kick, as well as cosmological constraints.Comment: 5 pages, 2 figures; final version; discussion and references adde

    Null Wilson loops with a self-crossing and the Wilson loop/amplitude conjecture

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    The present study illuminates the relation between null cusped Wilson loops and their corresponding amplitudes. We find that, compared to the case with no self-crossing, the one loop expectation value of a self-intersecting Wilson loop develops an additional 1/\epsilon singularity associated to the intersection. Interestingly, the same 1/\epsilon pole exists in the finite part of the one loop amplitude, appearing in the BDS conjecture, at the corresponding kinematic limit. At two loops, we explore the behaviour of the remainder function R, encoding the deviation of the amplitude from the BDS conjecture. By analysing the renormalisation group equations for the Wilson loop with a simple self-crossing, we argue that, when approaching the configuration with a self-crossing (u_2 \to 1, u_1\approx u_3), R diverges in the imaginary direction like R ~ i \pi \log^3(1-u_2). This behaviour can be attributed to the non-trivial analytic continuation needed when passing from the Euclidean to the physical region and suggests that R has a branch cut in the negative u_2 axis when the two other cross ratios are approximately equal (u_1 \approx u_3).Comment: 23 pages, 1 figure, typos corrected,references adde
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