Author Correction: A Model of the Cosmos in the ancient Greek Antikythera Mechanism (Scientific Reports, (2021), 11, 1, (5821), 10.1038/s41598-021-84310-w)

Correction to: Scientific Reports https://doi.org/10.1038/s41598-021-84310-w, published online 12 March 202

Defining new technological traditions of Late Islamic Arabia: a view on Bahlā Ware from al-Ain (UAE) and the lead-barium glaze production

In this paper, the monochrome glazed Bahlā Ware from al-Ain dated between the seventeenth and twentieth centuries (Late Islamic Arabian Period) has been analysed aiming to reconstruct the production technology of the ceramic fabrics and glazes. The results of the petrographic and chemical analyses suggest a unique technological tradition embedded in the culture of Late Islamic Arabia. This tradition incorporates the production of a lead-barium glaze coated over a single type of ceramic fabric that spans for nearly three centuries. Since this is the first evidence for the production of a lead-barium glaze in the Islamic World, the origins of this technology remain uncertain, but the results of the ceramic petrography identify the Omani Peninsula as the most likely source for the ceramic fabric. During the economic peak of al-Ain in the eighteenth century, this tradition shows signs of technological diversity visible in the appearance of new fabrics and glazes. Considering the wide distribution of Bahlā Ware in the Western Indian Ocean, understanding of the production technology and provenance of al-Ain’s ceramics has important implications for archaeological interpretation

Machine translation for subtitling: a large-scale evaluation

This article describes a large-scale evaluation of the use of Statistical Machine Translation for professional subtitling. The work was carried out within the FP7 EU-funded project SUMAT and involved two rounds of evaluation: a quality evaluation and a measure of productivity gain/loss. We present the SMT systems built for the project and the corpora they were trained on, which combine professionally created and crowd-sourced data. Evaluation goals, methodology and results are presented for the eleven translation pairs that were evaluated by professional subtitlers. Overall, a majority of the machine translated subtitles received good quality ratings. The results were also positive in terms of productivity, with a global gain approaching 40%. We also evaluated the impact of applying quality estimation and filtering of poor MT output, which resulted in higher productivity gains for filtered files as opposed to fully machine-translated files. Finally, we present and discuss feedback from the subtitlers who participated in the evaluation, a key aspect for any eventual adoption of machine translation technology in professional subtitlin

Researching with Twitter timeline data: A demonstration via “everyday” socio-political talk around welfare provision

Increasingly, social media platforms are understood by researchers to be valuable sites of politically-relevant discussions. However, analyses of social media data are typically undertaken by focusing on ‘snapshots’ of issues using query-keyword search strategies. This paper develops an alternative, less issue-based, mode of analysing Twitter data. It provides a framework for working qualitatively with longitudinally-oriented Twitter data (user-timelines), and uses an empirical case to consider the value and the challenges of doing so. Exploring how Twitter users place “everyday” talk around the socio-political issue of UK welfare provision, we draw on digital ethnography and narrative analysis techniques to analyse 25 user-timelines and identify three distinctions in users’ practices: users’ engagements with welfare as TV entertainment or as a socio-political concern; the degree of sustained engagement with said issues, and; the degree to which users’ tweeting practices around welfare were congruent with or in contrast to their other tweets. With this analytic orientation, we demonstrate how a longitudinal analysis of user-timelines provides rich resources that facilitate a more nuanced understanding of user engagement in everyday socio-political discussions online

Linear dichroism and circular dichroism in photosynthesis research

The efficiency of photosynthetic light energy conversion depends largely on the molecular architecture of the photosynthetic membranes. Linear- and circular-dichroism (LD and CD) studies have contributed significantly to our knowledge of the molecular organization of pigment systems at different levels of complexity, in pigment–protein complexes, supercomplexes, and their macroassemblies, as well as in entire membranes and membrane systems. Many examples show that LD and CD data are in good agreement with structural data; hence, these spectroscopic tools serve as the basis for linking the structure of photosynthetic pigment–protein complexes to steady-state and time-resolved spectroscopy. They are also indispensable for identifying conformations and interactions in native environments, and for monitoring reorganizations during photosynthetic functions, and are important in characterizing reconstituted and artificially constructed systems. This educational review explains, in simple terms, the basic physical principles, and theory and practice of LD and CD spectroscopies and of some related quantities in the areas of differential polarization spectroscopy and microscopy

Discursive constructions of language and identity: parents' competing perspectives in London Turkish complementary schools

In this paper, I draw on interview data to explore parents' constructions of language and identity in two London Turkish complementary schools. I examine parents' evaluative talk about standard Turkish, Cypriot-Turkish and other regional varieties of Turkish, the cultural values they attach to them and images of personhood these invoke. I demonstrate how parents brought up in Turkey and Cyprus tend to privilege standard Turkish and acknowledge the crucial role Turkish complementary schools play as one of the key vehicles for its spread and promotion. Some parents, however, especially those politically active in promoting Cypriot-Turkish language, culture and history to the British-born generation, voice an alternative discourse where Cypriot-Turkish is intimately linked to their sense of self. Moreover, I investigate parents' perspectives of their children and of their own Turkish language competence in the case of parents brought up in the UK. I illustrate how their Turkish and their children's are compared against a ‘native’ speaker norm firmly located in the countries of origin. The parents' accounts show how different self- and other-ascriptions of proficiency in Turkish are linked to claims of or lack of ‘Turkishness’, largely shaped by their migration histories and narratives, personal and professional transnational experiences

Curative in vivo hematopoietic stem cell gene therapy of murine thalassemia using large regulatory elements

Recently, we demonstrated that hematopoietic stem/progenitor cell (HSPC) mobilization followed by intravenous injection of integrating, helper-dependent adenovirus HDAd5/35++ vectors resulted in efficient transduction of long-term repopulating cells and disease amelioration in mouse models after in vivo selection of transduced HSPCs. Acute innate toxicity associated with HDAd5/35++ injection was controlled by appropriate prophylaxis, making this approach feasible for clinical translation. Our ultimate goal is to use this technically simple in vivo HSPC transduction approach for gene therapy of thalassemia major or sickle cell disease. A cure of these diseases requires high expression levels of the therapeutic protein (γ- or β-globin), which is difficult to achieve with lentivirus vectors because of their genome size limitation not allowing larger regulatory elements to be accommodated. Here, we capitalized on the 35 kb insert capacity of HDAd5/35++ vectors to demonstrate that transcriptional regulatory regions of the β-globin locus with a total length of 29 kb can efficiently be transferred into HSPCs. The in vivo HSPC transduction resulted in stable γ-globin levels in erythroid cells that conferred a complete cure of murine thalassemia intermedia. Notably, this was achieved with a minimal in vivo HSPC selection regimen