RESPONSE OF PUBLIC LAND RANCHERS TO POLICY CHANGES

Policy analysis and planning requires that we know what the likely responses of affected parties to given policy changes. We conducted a random survey of ranchers holding 1998 public land grazing permits in all western states to determine the social and economic characteristics of permit holders, to assess their attitudes about public land policies, and to gauge their responses to three policies related to public land grazing. Respondents were asked how their operations would change due to three different levels of AUM reductions, three different grazing fee increases, and to changes in allowed season of use. The respondents were clustered into eight different types of ranchers using management objective, education, business organization, ranch size, labor, income, and financial aspects. Perceived ranching objectives included preserving family tradition, culture, and values; raising family in a rural setting; living closer to friends and family; earning a good return on investment; avoiding difficulty obtaining a job outside the ranch due to skills; protecting environmental resources; and planning to pass business on to children. Based on the clusters, different policy choices will have differential impacts depending on the type of rancher and individual management goals. Their responses to the various policy choices indicate that analysis using the refined clusters will lead to a different impact assessment compared to using average responses for the population.Agricultural and Food Policy, Land Economics/Use,

AS-204/LM-1 launch vehicle operational flight trajectory

Apollo Saturn-204/LM-1 launch vehicle operational flight trajector

Safety and physiological effects of two different doses of elosulfase alfa in patients with morquio a syndrome: A randomized, double-blind, pilot study.

The primary treatment outcomes of a phase 2, randomized, double-blind, pilot study evaluating safety, physiological, and pharmacological effects of elosulfase alfa in patients with Morquio A syndrome are herewith presented. Patients aged ≥7 years and able to walk ≥200 m in the 6-min walk test (6MWT) were randomized to elosulfase alfa 2.0 or 4.0 mg/kg/week for 27 weeks. The primary objective was to evaluate the safety of both doses. Secondary objectives were to evaluate effects on endurance (6MWT and 3-min stair climb test [3MSCT]), exercise capacity (cardio-pulmonary exercise test [CPET]), respiratory function, muscle strength, cardiac function, pain, and urine keratan sulfate (uKS) levels, and to determine pharmacokinetic parameters. Twenty-five patients were enrolled (15 randomized to 2.0 mg/kg/week and 10 to 4.0 mg/kg/week). No new or unexpected safety signals were observed. After 24 weeks, there were no improvements versus baseline in the 6MWT, yet numerical improvements were seen in the 3MSCT with 4.0 mg/kg/week. uKS and pharmacokinetic data suggested no linear relationship over the 2.0-4.0 mg/kg dose range. Overall, an abnormal exercise capacity (evaluated in 10 and 5 patients in the 2.0 and 4.0 mg/kg/week groups, respectively), impaired muscle strength, and considerable pain were observed at baseline, and there were trends towards improvements in all domains after treatment. In conclusion, preliminary data of this small study in a Morquio A population with relatively good endurance confirmed the acceptable safety profile of elosulfase alfa and showed a trend of increased exercise capacity and muscle strength and decreased pain

Microseismicity and permeability enhancement of hydrogeologic structures during massive fluid injections into granite at 3 km depth at the Soultz HDR site

A high-rate injection of 20 000 m3 of water into granite between 2.8 and 3.4 km depth at the Soultz hot dry rock (HDR) test site in France in 1993 September led to a 200-fold increase in borehole transmissivity and produced a subvertical cloud of microseismicity of dimensions 0.5 km wide, 1.2 km long, 1.5 km high and oriented 25°NW. The resulting data set is unusually complete and well suited to studying permeability creation/enhancement processes in crystalline rock and the utility of microseismic data for revealing them. Although the microseismic cloud defined using joint hypocentre determination (JHD) locations was diffuse and showed little structure, application of the collapsing method showed it to be composed largely of discrete tubes and planes that propagated coherently. One prominent structure that extended 350 m downwards from the vicinity of a flow inlet early in the injection and that appears to contain a major flow path was subjected to detailed investigation to establish its hydrogeologic nature and the mechanisms underpinning its inferred permeability enhancement. High-resolution microseismic mapping techniques (i.e. multiplets and clustering) showed it to be a subvertical, NNW-SSE striking, fracture zone of width 10-20 m. The strike and scale of the structure identifies it as a member of a family of hydrothermally altered, cataclastic shear structures that constitute the primary permeable paths for fluid migration within the rock mass, both under ambient and forced fluid flow conditions. The microseismicity occurred on subvertical, small-scale fractures within the cataclastic shear zone whose azimuths scatter within 22° of parallel to the parent structure. Although the structure is likely to have been naturally permeable to some degree, its permeability appears to have been significantly enhanced as a consequence of the injection. The most likely mechanism of permeability enhancement, which is in accord with the strong preference for the microseismicity to grow downwards, involves strike-slip shearing, which produced the opening of vertical tubes at along-strike jogs in the fault (the so-called Hill mesh). Seismic moment release averaged over the structure suggests shear displacements of at least 0.3 mm occurred, which are sufficient to generate aperture changes that are hydraulically significant. The preponderance of discrete structures within the microseismic cloud after collapsing suggests that significant flow and permeability enhancement (i.e. stimulation) within the rock mass is largely confined to the interiors of shear zones that appear to have a spacing of approximately 100

The occurrence of escherichia coli in groundwater of bekasi city (Case Study: Jatiluhur, sumur batu, and jatirangga urban villages)

© 2020 Institute of Physics Publishing. All rights reserved. The self-supply of groundwater at the household level, and especially in densely populated areas, is vulnerable to fecal contamination. The aim of this study was to assess the level of fecal contamination in groundwater of three urban villages in Bekasi City that depend greatly on groundwater: Jatiluhur, Sumur Batu, and Jatirangga. Water samples were taken from 255 households with various types of water sources in the rainy season from February-March 2020. Escherichia coli (E. coli) concentration was quantified with Colilert-18 using IDEXX Quanti-Tray/2000 based on Most Probable Number (MPN) method. E. coli levels were beyond the WHO standard and found in 60% of the sources; 24% were above 100 MPN/100 mL. The presence of E. coli in groundwater indicated a requirement for further treatment prior to the point of consumption and an urgent need to replace the water supply infrastructure for improved water sources