328 research outputs found

    An Interactive Tool to Compare and Communicate Traffic Safety Risks: TrafficSTATS

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    TrafficSTATS (www.traffic-stats.us) is a publicly-available, interactive, web-based query tool that provides estimates of passenger vehicle and other traffic safety risks. Using "cube" database technology, TrafficSTATS houses publicly-available government data on traffic fatalities from the Fatality Analysis Reporting System (FARS) and personal travel behavior from the National Household Travel Survey (NHTS) and calculates risk statistics in real time for user-specified queries. We describe the motivation for developing the tool, explain the technology developed to store the data and facilitate the queries, and provide a series of examples of the types of comparisons that can be made quickly and efficiently

    Estimation of dominance variance in purebred Yorkshire swine

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    peer reviewedWe used 179,485 Yorkshire reproductive and 239,354 Yorkshire growth records to estimate additive and dominance variances by Method Fraktur R. Estimates were obtained for number born alive (NBA), 21-d litter weight (LWT), days to 104.5 kg (DAYS), and backfat at 104.5 kg (BF). The single-trait models for NBA and LWT included the fixed effects of contemporary group and regression on inbreeding percentage and the random effects mate within contemporary group, animal permanent environment, animal additive, and parental dominance. The single-trait models for DAYS and BF included the fixed effects of contemporary group, sex, and regression on inbreeding percentage and the random effects litter of birth, dam permanent environment, animal additive, and parental dominance. Final estimates were obtained from six samples for each trait. Regression coefficients for 10% inbreeding were found to be -.23 for NBA, -.52 kg for LWT, 2.1 d for DAYS, and 0 mm for BF. Estimates of additive and dominance variances expressed as a percentage of phenotypic variances were, respectively, 8.8 +/- .5 and 2.2 +/- .7 for NBA, 8.1 +/- 1.1 and 6.3 +/- .9 for LWT, 33.2 +/- .4 and 10.3 +/- 1.5 for DAYS, and 43.6 +/- .9 and 4.8 +/- .7 for BF. The ratio of dominance to additive variances ranged from .78 to .11

    Neuroblastic tumors of the adrenal gland in elderly patients: a case report and review of the Literature

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    Background: Neuroblastic neoplasms (NN) include ganglioneuromas (GN), ganglioneuroblastomas (GNB), and neuroblastomas (NB). They generally arise in childhood from primitive sympathetic ganglion cells. Their incidence in adults, especially among elderly, is extremely low. Case Presentation: This is the case of a 74-year-old woman with history of abdominal pain, weakness and night sweating since several months. Blood pressure was normal. CT-scan showed a 10 cm left adrenal mass, without other pathologic findings. An open left-sided adrenalectomy was performed. Recovery was uneventful with hospital length of stay of 8 days. Based on morphological, immunohistochemical, and molecular features the diagnosis was a nodular GNB. A positron emission tomography (PET) performed 6 weeks after the resection did not show any residual tumor or distant metastases. The patient was followed-up with annual clinical and radiological exams. Conclusion: This case presentation, associated with a review of the literature, illustrates the importance to include NN in the preoperative differential diagnosis of adrenal tumors in adults and highlights the need for multidisciplinary patient work-up and management

    Prediction of the individual enteric methane emission of dairy cows from milk mid-infrared spectra

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    peer reviewedThe livestock sector is considered the largest producer of methane (CH4) from anthropogenic sources, world wide contributing 37% of emissions (FAO, 2006). An important step to study and develop mitigation methods for livestock emissions is to be able to measure them on a large scale. However, it is difficult to obtain a large number of individual CH4 measurements with the currently available techniques (chambers or SF6). The aim of this study was to develop a high throughput tool for determination of CH4 emissions from dairy cows. Anaerobic fermentation of food in the reticulorumen is the basis of enteric CH4 production. End-products of that enteric fermentation can be found in the milk (e.g., volatile fatty acids). Therefore individual enteric CH4 emissions could be quantified from whole milk mid-infrared (MIR) spectra which reflect milk composition and can be obtained at low cost (e.g., national milk recording). Prediction equations of individual CH4 emissions (determined using the SF6 method) from milk MIR spectra have been established (Dehareng et al., 2012; Soyeurt et al., 2013). The results presented here are the improvement of this methodology by using a multiple breed and country approach

    Invited review: From heat stress to disease-Immune response and candidate genes involved in cattle thermotolerance.

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    peer reviewedHeat stress implies unfavorable effects on primary and functional traits in dairy cattle and, in consequence, on the profitability of the whole production system. The increasing number of days with extreme hot temperatures suggests that it is imperative to detect the heat stress status of animals based on adequate measures. However, confirming the heat stress status of an individual is still challenging, and, in consequence, the identification of novel heat stress biomarkers, including molecular biomarkers, remains a very relevant issue. Currently, it is known that heat stress seems to have unfavorable effects on immune system mechanisms, but this information is of limited use in the context of heat stress phenotyping. In addition, there is a lack of knowledge addressing the molecular mechanisms linking the relevant genes to the observed phenotype. In this review, we explored the potential molecular mechanisms explaining how heat stress affects the immune system and, therefore, increases the occurrence of immune-related diseases in cattle. In this regard, 2 relatively opposite hypotheses are under focus: the immunosuppressive action of cortisol, and the proinflammatory effect of heat stress. In both hypotheses, the modulation of the immune response during heat stress is highlighted. Moreover, it is possible to link candidate genes to these potential mechanisms. In this context, immune markers are very valuable indicators for the detection of heat stress in dairy cattle, broadening the portfolio of potential biomarkers for heat stress

    Estimating internal pelvic sizes using external body measurements in the double-muscled Belgian Bleu beef breed

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    In the double-muscled (DM) Belgian Blue beef (BBB) breed, caesarean section (CS) is being applied systematically as a management tool to prevent dystocia. As a matter of fact, CS is the only possible way of calving in the breed. High birth weight and a relatively small pelvic area are the main causes of dystocia and, in the DM-BBB breed, the reasons for the systematically applied CS. Selection for lower birth weight and larger pelvic sizes might reduce dystocia and routine CS. Few data on inner pelvic sizes of pedigree animals are available. Using external measurements to estimate the inner pelvic sizes might be an option to resolve this problem. In this study, animals of the DM-BBB breed were measured and weighed on farms and in abattoirs. External and internal pelvic sizes increased with live weight and age of the animals. Gender had a significant influence on inner pelvic traits. Increased muscular conformation was associated with decreased inner pelvic dimensions. Models with weight, gender, age, withers height and outer pelvic width (TcTc) can be used to estimate inner pelvic sizes (R-2 between 0.35 and 0.77). The estimated inner pelvic sizes can then be used to genetically evaluate pelvic traits in the DM-BBB breed. Improving weight, withers height and TcTc width in combination with lowering muscular conformation may help to decrease the high rate of caesarean section in the DM-BBB
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