9 research outputs found
Spatiotemporal scaling of North American continental interior wetlands: implications for shorebird conservation
Within interior North America, erratic weather patterns and heterogeneous wetland complexes cause wide spatio-temporal variation in the resources available to migrating shorebirds. Identifying the pattern-generating components of landscape-level resources and the scales at which shorebirds respond to these patterns will better facilitate conservation efforts for these species. We constructed descriptive models that identified weather variables associated with creating the spatio-temporal patterns of shorebird habitat in ten landscapes in north-central Oklahoma. We developed a metric capable of measuring the dynamic composition and configuration of shorebird habitat in the region and used field data to empirically estimate the spatial scale at which shorebirds respond to the amount and configuration of habitat. Precipitation, temperature, solar radiation and wind speed best explained the incidence of wetland habitat, but relationships varied among wetland types. Shorebird occurrence patterns were best explained by habitat density estimates at a 1.5 km scale. This model correctly classified 86 % of shorebird observations. At this scale, when habitat density was low, shorebirds occurred in 5 % of surveyed habitat patches but occurrence reached 60 % when habitat density was high. Our results suggest scale dependence in the habitat-use patterns of migratory shorebirds. We discuss potential implications of our results and how integrating this information into conservation efforts may improve conservation strategies and management practices
Spatiotemporal scaling of North American continental interior wetlands: implications for shorebird conservation
Characteristics within and around stopover wetlands used by migratory shorebirds: Is the neighborhood important?
Broad-scale relationships between shorebirds and landscapes in the southern Great Plains
Stopover use by migrating shorebirds is affected by patch-level characteristics of habitat, but the relative influence of broad-scale factors is poorly understood. We conducted surveys of ten 10-km-radius landscapes in north-central Oklahoma from 2007 through 2009 to examine the influence of the amount and composition of wetland habitats and surrounding land cover on shorebird use during migration. We used generalized linear modeling and an information-theoretic framework to identify factors that best explained species richness, total abundance, and abundance of four groups of shorebirds classified by breeding status and migration distance. Total abundance and richness both increased with the area of wetland habitat within a landscape, regardless of the composition of semi-natural and developed land cover surrounding wetlands. Abundance of shorebird species with different migration strategies varied in relation to the composition of wetland types within a landscape. The amounts of various permanent and semi-permanent wetlands best explained abundance of resident species. Short-distance migrant abundance was best explained by the amount of permanent lacustrine wetlands. The amounts of temporary and semipermanent floodwater habitats were important predictors for abundance of intermediate- and long-distance migrants, although permanent riverine habitats were also important for intermediate-distance migrants. Shorebird species richness was best explained by the amounts of floodwater habitats and permanent riverine wetlands. Broad-scale studies thus provide important insights on use of stopover habitats by migratory shorebirds. Within this region, conservation of riverine habitats with a large complement of ephemeral habitats is necessary to provide the stopover habitat for migrating shorebirds
Differential expression of striatal proteins in a mouse model of DOPA-responsive dystonia reveals shared mechanisms among dystonic disorders
GBA-Related Parkinson's Disease: Dissection of Genotype–Phenotype Correlates in a Large Italian Cohort
Background: Variants in GBA are the most common genetic risk factor for Parkinson's disease (PD). The impact of different variants on the PD clinical spectrum is still unclear. Objectives: We determined the frequency of GBA-related PD in Italy and correlated GBA variants with motor and nonmotor features and their occurrence over time. Methods: Sanger sequencing of the whole GBA gene was performed. Variants were classified as mild, severe, complex, and risk. β-glucocerebrosidase activity was measured. The Kaplan-Meier method and Cox proportional hazard regression models were performed. Results: Among 874 patients with PD, 36 variants were detected in 14.3%, including 20.4% early onset. Patients with GBA-PD had earlier and more frequent occurrence of several nonmotor symptoms. Patients with severe and complex GBA-PD had the highest burden of symptoms and a higher risk of hallucinations and cognitive impairment. Complex GBA-PD had the lowest β-glucocerebrosidase activity. Conclusions: GBA-PD is highly prevalent in Italy. Different types of mutations underlie distinct phenotypic profiles. © 2020 International Parkinson and Movement Disorder Society