Cyclic universe due to phantom and quintessence

We explore a cyclic universe due to phantom and quintessence fields. We find that, in every cycle of the evolution of the universe, the phantom dominates the cosmic early history and quintessence dominates the cosmic far future. In this model of universe, there are infinite cycles of expansion and contraction. Different from the inflationary universe, the corresponding cosmic space-time is geodesically complete and quantum stable. But similar to the Cyclic Model, the flatness problem, the horizon problem and the large scale structure of the universe can be explained in this cyclic universe.Comment: 8 pages, 5 figures. To appear in GR

Comparisons of MVAC and MVDC systems in dynamic operation, fault protection and post-fault restoration

One of the most significant obstacles preventing the large-scale application of direct-current (DC) technology in medium voltage (MV) distribution networks is their fault protection. The existing AC relay protection needs to be changed or redesigned to protect the future overlay MVAC and MVDC distribution networks. Therefore, a comprehensive understanding of the dynamic and fault behavior and post-fault restoration strategies of MVAC and MVDC systems are critically important. Moreover, a comparison of MVAC and MVDC systems during a fault will also contribute to designing the protection systems of hybrid MV AC/DC systems. In this paper, the challenges of protecting DC faults of MVDC systems and possible solutions are first introduced. Then, the fault characteristics and post-fault restoration of MVDC and MVAC distribution systems are compared and investigated through case studies. Time-domain simulations have been conducted in PSCAD/EMTDC. The work in this paper will be valuable for the protection design for future hybrid MV AC/DC systems

Characterization of variants in the promoter of BZLF1 gene of EBV in nonmalignant EBV-associated diseases in Chinese children

<p>Abstract</p> <p>Background</p> <p>Diseases associated with Epstein-Barr virus (EBV) infections, such as infectious mononucleosis (IM), EBV-associated hemophagocytic lymphohistiocytosis (EBV-HLH) and chronic active EBV infection (CAEBV) are not rare in Chinese children. The association of type 1 or type 2 EBV and variants of the EBV BZLF1 promoter zone (Zp) with these diseases is unclear.</p> <p>Results</p> <p>The objective of this study was to investigate the relationship between EBV genotypes (Zp variants and EBV type 1 and 2) and the clinical phenotypes of EBV-associated diseases in Chinese children. The Zp region was directly sequenced in 206 EBV-positive DNA samples from the blood of patients with IM, EBV-HLH, CAEBV, and healthy controls. Type 1 or type 2 EBV was examined by PCR for EBNA2 and EBNA3C subtypes. Four polymorphic Zp variants were identified: Zp-P, Zp-V3, Zp-P4 and Zp-V1, a new variant. The Zp-V3 variant was significantly associated with CAEBV (<it>P </it>≤ 0.01). The frequency of co-infection with Zp variants was higher in patients with CAEBV and EBV-HLH, compared with IM and healthy controls, mostly as Zp-P+V3 co-infection. Type 1 EBV was predominant in all categories (81.3-95%) and there was no significant difference in the frequency of the EBV types 1 and 2 in different categories (<it>P </it>> 0.05).</p> <p>Conclusions</p> <p>Type 1 EBV and BZLF1 Zp-P of EBV were the predominant genotypes in nonmalignant EBV associated diseases in Chinese children and Zp-V3 variant may correlates with the developing of severe EBV infection diseases, such as CAEBV and EBV-HLH.</p

Combination Therapy With Fingolimod and Neural Stem Cells Promotes Functional Myelination

Myelination, which occurs predominantly postnatally and continues throughout life, is important for proper neurologic function of the mammalian central nervous system (CNS). We have previously demonstrated that the combination therapy of fingolimod (FTY720) and transplanted neural stem cells (NSCs) had a significantly enhanced therapeutic effect on the chronic stage of experimental autoimmune encephalomyelitis, an animal model of CNS autoimmunity, compared to using either one of them alone. However, reduced disease severity may be secondary to the immunomodulatory effects of FTY720 and NSCs, while whether this therapy directly affects myelinogenesis remains unknown. To investigate this important question, we used three myelination models under minimal or non-inflammatory microenvironments. Our results showed that FTY720 drives NSCs to differentiate into oligodendrocytes and promotes myelination in an ex vivo brain slice culture model, and in the developing CNS of healthy postnatal mice in vivo. Elevated levels of neurotrophic factors, e.g., brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor, were observed in the CNS of the treated infant mice. Further, FTY720 and NSCs efficiently prolonged the survival and improved sensorimotor function of shiverer mice. Together, these data demonstrate a direct effect of FTY720, beyond its known immunomodulatory capacity, in NSC differentiation and myelin development as a novel mechanism underlying its therapeutic effect in demyelinating diseases

A MEASUREMENT SYSTEM OF HUMAN-BODY CONSTITUTION AND STRENGTH EXERCISE

This paper introduces a measurement and training system based on sensors, computer software and hardware for body constitution measurement and strength training. The system adopts the sensor technology, computer software and hardware technology, as well as digital display technology to perform automatic data collection and processing in real time in order to enhance the system accuracy and the running efficiency. The measurement errors caused by the staff members, who are over-involved in measurements and by the original equipment, are greatly reduced. According to the measured data, physical educators and instructors can make informed decisions and readjust the items of physical education, by observing the changes in body constitution before and after the exercise. This system is helpful for formulation of a scientific exercise plan and to improve exercise effectiveness

NCOS and D-branes in Time-dependent Backgrounds

We study noncommutative open string (NCOS) theories realized in string theory with time-dependent backgrounds. Starting from a noncommutative Yang-Mills theory (NCYM) with a constant space-space noncommutativity but in a time-dependent background and making an S-dual transformation, we show that the resulting theory is an NCOS also in a time-dependent background but now with a time-dependent time-space noncommutativity and a time-dependent string scale. The corresponding dual gravity description is also given. A general SL(2,Z) transformation on the NCYM results in an NCOS with a time-dependent time-space noncommutativity and a constant space-space noncommutativity, and also in a time-dependent background.Comment: 12 pages, references added; v3: minor correction, to appear in PL

Comparative investigation of damage induced by diatomic and monoatomic ion implantation in silicon

The damaging effect of mono- and diatomic phosphorus and arsenic ions implanted into silicon was investigated by spectroscopic ellipsometry (SE) and high-depth-resolution Rutherford backscattering and channeling techniques. A comparison was made between the two methods to check the capability of ellipsometry to examine the damage formed by room temperature implantation into silicon. For the analysis of the spectroscopic ellipsometry data we used the conventional method of assuming appropriate optical models and fitting the model parameters (layer thicknesses and volume fractions of the amorphous silicon component in the layers) by linear regression. The depth dependence of the damage was determined by both methods. It was revealed that SE can be used to investigate the radiation damage of semiconductors together with appropriate optical model construction which can be supported or independently checked by the channeling method. However, in case of low level damage (consisting mainly of isolated point defects) ellipsometry can give false results, overestimating the damage using inappropriate dielectric functions. In that case checking by other methods like channeling is desirable