9 research outputs found

    Analysis of classroom teachers’ storytelling in teaching mathematical skills : Storytelling in teaching mathematical skills

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    The storytelling method is one of the important ways that removes the obstacles to learning mathematics and makes it an understandable lesson. In this research, it is aimed that primary school teachers design stories for students to gain concepts about problem solving, fluency, reasoning and understanding skills. The study is a qualitative case study and the participants are 25 classroom teachers. The data were analyzed descriptively through qualitative programs. According to the results of the research, teachers can teach mathematical skills and the achievements in the international mathematics curriculum through storytelling. However, in their stories, they limitedly refer to the acquisitions that will enable them to relate to other courses such as teaching interdisciplinary concepts and object modeling. As a result of the study, it can be recommended to increase the awareness of teachers in in-service training or in undergraduate courses of teacher candidates on subjects such as the acquisition of mathematical skills, modeling and teaching interdisciplinary concepts. For this, alternative methods and techniques such as storytelling can be used

    Protein oxidation markers in women with and without gestational diabetes mellitus: A possible relation with paraoxonase activity

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    Uzun, Hafize/0000-0002-1347-8498; Gelisgen, Remise/0000-0003-4121-5107; Cakatay, Ufuk/0000-0001-9861-7380; Guralp, Onur/0000-0002-3517-3046WOS: 000298144400021PubMed: 21885148Aims: To clarify the levels of protein oxidation markers such as protein carbonyl (PCO), protein hydroperoxides (P-OOH), advanced oxidation protein products (AOPP) and nitrotyrosine (NT), as well as antioxidative enzymes such as paraoxonase (PON-1) in women with and without gestational diabetes mellitus (GDM). Methods: The study was conducted on 23 women with GDM and 22 women without GDM. The levels of the P-OOH, AOPP, and PON-1 were determined by colorimetric methods; whereas NT and PCO levels were measured by ELISA. Results: The concentrations of protein oxidation markers were significantly increased and PON1 activity was significantly decreased in GDM group compared to those of normal pregnant women. The control group showed a significant negative correlation between PON-1 and PCO (r = -0.451, p = 0.027); whereas in GDM group, there was a significant positive correlation between P-OOH and HbA1c (r = 0.89, p = 0.001). There was no significant correlation between AOPP, PON-1, P-OOH, PCO, and HbA1c in either group. Conclusions: There is evidence of a possible association between protein oxidation and decreased PON1 activity in GDM. The increase in protein oxidation parameters in the GDM group leading to decreased PON1 activity might, we think, create a predisposition for clinical complications in GDM group. (C) 2011 Elsevier Ireland Ltd. All rights reserved.Istanbul UniversityIstanbul University [BYP-871/23122005]This work was supported by The Research Fund of Istanbul University (Project number: BYP-871/23122005)

    Evaluation of oxidative stress markers in first trimester for assessment of preeclampsia risk.

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    The aim of this study is to determine the predictive values of oxidative stress markers and antioxidants in the development of preeclampsia between 10-14 and also at 20-24 weeks of gestation, after the completion of vascular transformation

    Deneysel etanol uygulamasında darbepoetin alfanın beyin dokusu oksidatif stresi üzerine etkileri

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    İstanbul Bilim Üniversitesi, Tıp Fakültesi.Objectives: The hyperglycosylated erythropoietin analogue darbepoetin alpha (α) has longer half-life and higher in vivo activity. There is no data about the effects of darbepoetin-α on ethanol-induced oxidative stress. In this study, we investigated the effects of darbepoetin-α on brain tissue oxidant/antioxidant status and nitric oxide levels in experimental ethanol administration. Patients and Methods: Forty-four adult male Wistar albino rats were randomly divided into groups: salinetreated group (S) (n=10), saline and darbepoetintreated group (D) (10 μg/kg) (n=10), experimental ethanol-administered [2.5 g/kg (2.6 ml/kg) twice at 2-hr intervals] group (E) (n=12), ethanol-administered and darbepoetin-treated group (ED) (n=12).Amaç: Eritropoetin analoğu darbepoetin alfa, yarı ömrü uzun ve in vivo yüksek aktiviteye sahip bir moleküldür. Alkolün etkili olduğu organizmada darbepoetinin etkisi henüz ortaya konulmamıştır. Bu çalışmada, deneysel etanol uygulamasında darbepoetin alfanın beyin dokusu oksidan/antioksidan denge ve nitrik oksit seviyesi üzerine etkilerini araştırdık. Hastalar ve Yöntemler: Kırk dört erişkin erkek Wistar Albino sıçan raslantısal olarak gruplara ayrıldı: %0.9 NaCl uygulanan grup (S) (n=10), %0.9 NaCl ve darbepoetin verilen grup (D) (10 μg /kg) (n=10), deneysel etanol uygulaması yapılan [2.5 g/kg (2.6 ml/kg) 2-saatlik aralıklar ile iki defa] grup (E) (n=12), etanol uygulanan ve darbepoetin verilen grup (ED) (n=12)
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