Pre-equilibrium dileptons look thermal

The dilepton mass distribution from pre-equilibrium matter in ultrarelativistic nuclear collisions is indistinguishable from a thermally produced distribution.Comment: CERN-TH.6813/93, 3 pages (latex) plus 1 figure (uuencoded postscript file

Heavy resonance production in high energy nuclear collisions

We estimate freezeout conditions for $s$, $c$, and $b$ quarks in high energy nuclear collisions. Freezeout is due either to loss of thermal contact, or to particles ``wandering'' out of the region of hot matter. We then develop a thermal recombination model in which both single-particle (quark and antiquark) and two-particle (quark-antiquark) densities are conserved. Conservation of two-particle densities is necessary because quarks and antiquarks are always produced in coincidence, so that the local two-particle density can be much larger than the product of the single-particle densities. We use the freezeout conditions and recombination model to discuss heavy resonance production at zero baryon density in high energy nuclear collisions.Comment: revtex, 15 pages, no figures, KSUCNR-009-9

A C-13(alpha,n)O-16 calibration source for KamLAND

We report on the construction and performance of a calibration source for KamLAND using the reaction C-13(alpha,n)O-16 with Po-210 as the alpha progenitor. The source provides a direct measurement of this background reaction in our detector, high energy calibration points for the detector energy scale, and data on quenching of the neutron visible energy in KamLAND scintillator. We also discuss the possibility of using the reaction C-13(alpha,n)O-16 as a source of tagged slow neutrons.Comment: 6 pages, 4 figures. Revised to agree with the published tex

2-(Thio­phen-2-yl)-1-(thio­phen-2-ylmeth­yl)-1H-benzimidazole

In the title compound, C16H12N2S2, the thio­phene groups are rotationally disordered over two sets of sites, by approximately 180°, with occupancy ratios of 0.916 (2):0.084 (2) and 0.903 (2):0.097 (2). The major components of the thio­phene and methyl­ene substituted thio­phene rings are canted by 24.06 (12) and 85.07 (10)°, respectively, from the benzimidazole ring system plane and the dihedral angle between the major component thio­phene ring planes is 84.90 (14)°. In the crystal, there is a weak C—H⋯N hydrogen bond which links mol­ecules into chains

Thermal quark production in ultra-relativistic nuclear collisions

We calculate thermal production of u, d, s, c and b quarks in ultra-relativistic heavy ion collisions. The following processes are taken into account: thermal gluon decay (g to ibar i), gluon fusion (g g to ibar i), and quark-antiquark annihilation (jbar j to ibar i), where i and j represent quark species. We use the thermal quark masses, $m_i^2(T)\simeq m_i^2 + (2g^2/9)T^2$, in all the rates. At small mass ($m_i(T)<2T$), the production is largely dominated by the thermal gluon decay channel. We obtain numerical and analytic solutions of one-dimensional hydrodynamic expansion of an initially pure glue plasma. Our results show that even in a quite optimistic scenario, all quarks are far from chemical equilibrium throughout the expansion. Thermal production of light quarks (u, d and s) is nearly independent of species. Heavy quark (c and b) production is quite independent of the transition temperature and could serve as a very good probe of the initial temperature. Thermal quark production measurements could also be used to determine the gluon damping rate, or equivalently the magnetic mass.Comment: 14 pages (latex) plus 6 figures (uuencoded postscript files); CERN-TH.7038/9

Coexistence of Spin Canting and Metamagnetism in a One-Dimensional Mn(II) Compound Bridged by Alternating Double End-to-End and Double End-On Azido Ligands and the Analog Co(II) Compound

Two new compounds of general formula [M(N3)2(dmbpy)] in which dmbpy = 5,5′-dimethyl-2,2′-bipyridine, and M = Mn(II) or Co(II), have been solvothermally synthesized and characterized structurally and magnetically. The structures consist of zig-zag polymeric chains with alternating bis-µ(azide-N1)2M and bis-µ(azide-N1,N3)2M units in which the cis-octahedrally based coordination geometry is completed by the N,N’-chelating ligand dmbpy. The molecular structures are basically the same for each metal. The Mn(II) compound has a slightly different packing mode compared to the Co(II) compound, resulting from their different space groups. Interestingly, relatively weak interchain interactions are present in both compounds and this originates from π–π stacking between the dmbpy rings. The magnetic properties of both compounds have been investigated down to 2 K. The measurements indicate that the manganese compound shows spin-canted antiferromagnetic ordering with a Néel temperature of TN = 3.4 K and further, a field-induced magnetic transition of metamagnetism at temperatures below the TN. This finding affords the first example of an 1D Mn(II) compound with alternating double end-on (EO) and double end-to-end (EE) azido-bridged ligands, showing the coexistence of spin canting and metamagnetism. The cobalt compound shows a weak ferromagnetism resulting from a spin-canted antiferromagnetism and long-range magnetic ordering with a critical temperature, TC = 16.2 K

Thermal photon production in high-energy nuclear collisions

We use a boost-invariant one-dimensional (cylindrically symmetric) fluid dynamics code to calculate thermal photon production in the central rapidity region of S+Au and Pb+Pb collisions at SPS energy ($\sqrt{s}=20$ GeV/nucleon). We assume that the hot matter is in thermal equilibrium throughout the expansion, but consider deviations from chemical equilibrium in the high temperature (deconfined) phase. We use equations of state with a first-order phase transition between a massless pion gas and quark gluon plasma, with transition temperatures in the range $150 \leq T_c \leq 200$ MeV.Comment: revised, now includes a_1 contribution. revtex, 10 pages plus 4 figures (uuencoded postscript

Reduced Intestinal Tumorigenesis in APCmin Mice Lacking Melanin-Concentrating Hormone

Background: Melanin-concentrating hormone (MCH) is an evolutionary conserved hypothalamic neuropeptide that in mammals primarily regulates appetite and energy balance. We have recently identified a novel role for MCH in intestinal inflammation by demonstrating attenuated experimental colitis in MCH deficient mice or wild type mice treated with an anti-MCH antibody. Therefore, targeting MCH has been proposed for the treatment of inflammatory bowel disease. Given the link between chronic intestinal inflammation and colorectal cancer, in the present study we sought to investigate whether blocking MCH might have effects on intestinal tumorigenesis that are independent of inflammation. Methodology Tumor development was evaluated in MCH-deficient mice crossed to the APCmin mice which develop spontaneously intestinal adenomas. A different cohort of MCH−/− and MCH+/+ mice in the APCmin background was treated with dextran sodium sulphate (DSS) to induce inflammation-dependent colorectal tumors. In Caco2 human colorectal adenocarcinoma cells, the role of MCH on cell survival, proliferation and apoptosis was investigated. Results: APCmin mice lacking MCH developed fewer, smaller and less dysplastic tumors in the intestine and colon which at the molecular level are characterized by attenuated activation of the wnt/beta-catenin signaling pathway and increased apoptotic indices. Form a mechanistic point of view, MCH increased the survival of colonic adenocarcinoma Caco2 cells via inhibiting apoptosis, consistent with the mouse studies. Conclusion: In addition to modulating inflammation, MCH was found to promote intestinal tumorigenesis at least in part by inhibiting epithelial cell apoptosis. Thereby, blocking MCH as a therapeutic approach is expected to decrease the risk for colorectal cancer

A Comparison of U. S. and European University-Industry Relations in the Life Sciences

We draw on diverse data sets to compare the institutional organization of upstream life science research across the United States and Europe. Understanding cross-national differences in the organization of innovative labor in the life sciences requires attention to the structure and evolution of biomedical networks involving public research organizations (universities, government laboratories, nonprofit research institutes, and research hospitals), science-based biotechnology firms, and multinational pharmaceutical corporations. We use network visualization methods and correspondence analyses to demonstrate that innovative research in biomedicine has its origins in regional clusters in the United States and in European nations. But the scientific and organizational composition of these regions varies in consequential ways. In the United States, public research organizations and small firms conduct R&D across multiple therapeutic areas and stages of the development process. Ties within and across these regions link small firms and diverse public institutions, contributing to the development of a robust national network. In contrast, the European story is one of regional specialization with a less diverse group of public research organizations working in a smaller number of therapeutic areas. European institutes develop local connections to small firms working on similar scientific problems, while cross-national linkages of European regional clusters typically involve large pharmaceutical corporations. We show that the roles of large and small firms differ in the United States and Europe, arguing that the greater heterogeneity of the U. S. system is based on much closer integration of basic science and clinical development