1,571 research outputs found

    Effect of Fodder Demonstrations in Rainfed Multi-location Conditions of Uttar Pradesh and Uttarakhand

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    Presently green fodder availability is 64.66 M tons and dry fodder (64.23 M tons.) in Uttar Pradesh, India., the green fodder deficit is 28.3% and dry fodder surplus by 14.1% respectively. Whereas, in Uttrakhand. Green fodder availability is 4.07 M tons and dry fodder 2.83 M tons, green fodder deficit is 48.1% and dry fodder 42.1%. There are many limitations affecting the forage production such as small holding of farmers and preferential need of food grains crops, limited availability of quality seed of improved varieties of fodder crops, low priority for investment in fodder production by the farmers. There is varied problem soils (acid, salt affected and water logged) prevailing in the area, lack of post harvest management for surplus fodder, no priority for fodder seed production by the farmers/seed producing agencies, no MSP for any of the fodder crops and lack of mechanization in fodder farming. Therefore, Nation Initiative on Fodder Technology Demonstrations will focus on increasing productivity through adoption of improved and appropriate technology best suited to the agro-climatic conditions in the zone in both arable and non-arable land. The objective of the technology demonstration is i). Accelerating production of fodder through promotion of fodder production, conservation and utilization enhancing the availability of the fodder throughout the year ii). Developing seed and planting material demonstrations units at KVK for fulfill the requirements of their vicinity. iii). Establishing back ward and forward linkages with different stake holders for profitable forage based life style husbandry

    Protein kinase CĪ¶ regulates phospholipase D activity in rat-1 fibroblasts expressing the Ī±(1A )adrenergic receptor

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    BACKGROUND: Phenylephrine (PHE), an Ī±(1 )adrenergic receptor agonist, increases phospholipase D (PLD) activity, independent of classical and novel protein kinase C (PKC) isoforms, in rat-1 fibroblasts expressing Ī±(1A )adrenergic receptors. The aim of this study was to determine the contribution of atypical PKCĪ¶ to PLD activation in response to PHE in these cells. RESULTS: PHE stimulated a PLD activity as demonstrated by phosphatidylethanol production. PHE increased PKCĪ¶ translocation to the particulate cell fraction in parallel with a time-dependent decrease in its activity. PKCĪ¶ activity was reduced at 2 and 5 min and returned to a sub-basal level within 10ā€“15 min. Ectopic expression of kinase-dead PKCĪ¶, but not constitutively active PKCĪ¶, potentiated PLD activation elicited by PHE. A cell-permeable pseudosubstrate inhibitor of PKCĪ¶ reduced basal PKCĪ¶ activity and abolished PHE-induced PLD activation. CONCLUSION: Ī±(1A )adrenergic receptor stimulation promotes the activation of a PLD activity by a mechanism dependent on PKCĪ¶; Our data also suggest that catalytic activation of PKCĪ¶ is not required for PLD stimulation

    What do We Know the Snow Darkening Effect Over Himalayan Glaciers?

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    The atmospheric absorbing aerosols such as dust, black carbon (BC), organic carbon (OC) are now well known warming factors in the atmosphere. However, when these aerosols deposit onto the snow surface, it causes darkening of snow and thereby absorbing more energy at the snow surface leading to the accelerated melting of snow. If this happens over Himalayan glacier surface, the glacier meltings are expected and may contribute the mass balance changes though the mass balance itself is more complicated issue. Glacier has mainly two parts: ablation and accumulation zones. Those are separated by the Equilibrium Line Altitude (ELA). Above and below ELA, snow accumulation and melting are dominant, respectively. The change of ELA will influence the glacier disappearance in future. In the Himalayan region, many glacier are debris covered glacier at the terminus (i.e., in the ablation zone). Debris is pieces of rock from local land and the debris covered parts are probably not affected by any deposition of the absorbing aerosols because the snow surface is already covered by debris (the debris covered parts have different mechanism of melting). Hence, the contribution of the snow darkening effect is considered to be most important "over non debris covered part" of the Himalayan glacier (i.e., over the snow or ice surface area). To discuss the whole glacier retreat, mass balance of each glacier is most important including the discussion on glacier flow, vertical compaction of glacier, melting amount, etc. The contribution of the snow darkening is mostly associated with "the snow/ice surface melting". Note that the surface melting itself is not always directly related to glacier retreats because sometimes melt water refreezes inside of the glacier. We should discuss glacier retreats in terms of not only the snow darkening but also other contributions to the mass balance

    Naturally split supersymmetry

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    Nonobservation of superparticles till date, new Higgs mass limits from the CMS and ATLAS experiments, WMAP constraints on relic density, various other low energy data, and the naturalness consideration, all considered simultaneously imply a paradigm shift of supersymmetric model building. In this paper we perform, for the first time, a detailed numerical study of brane-world induced supersymmetry breaking for both minimal and next-to-minimal scenarios. We observe that a naturally hierarchical spectrum emerges through an interplay of bulk, brane-localized and quasi-localized fields, which can gain more relevance in the subsequent phases of the LHC run.Comment: 6 pages, 6 eps figures; v2: minor updates, to appear in JHE

    The systematic study of the influence of neutron excess on the fusion cross sections using different proximity-type potentials

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    Using different types of proximity potentials, we have examined the trend of variations of barrier characteristics (barrier height and its position) as well as fusion cross sections for 50 isotopic systems including various collisions of C, O, Mg, Si, S, Ca, Ar, Ti and Ni nuclei with 1ā‰¤N/Z<1.61\leq N/Z < 1.6 condition for compound systems. The results of our studies reveal that the relationships between increase of barrier positions and decrease of barrier heights are both linear with increase of N/ZN/Z ratio. Moreover, fusion cross sections also enhance linearly with increase of this ratio.Comment: 28 pages, 7 figures, 5 Table

    Nanocrystals of metals, semiconductors and oxides: novel synthesis and applications

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    Films of nanocrystals such as Au, Ag and Pd, semiconducting sulphides such as CdS, ZnS and CoS, and oxides such as Fe2O3 and CuO have been prepared by employing reactions at liquid-liquid (organic-aqueous) interfaces. In this method, a suitable organic derivative of the metal taken in the organic layer reacts at the interface with the appropriate reagent present in the organic layer. Two typical applications of nanocrystals pertaining to magnetic devices and dip-pen lithography are briefly presented

    Human surfactant protein D alters oxidative stress and HMGA1 expression to induce p53 apoptotic pathway in eosinophil leukemic cell line

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    This article is made available through the Brunel Open Access Publishing Fund. Copyright: Ā© 2013 Mahajan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Surfactant protein D (SP-D), an innate immune molecule, has an indispensable role in host defense and regulation of inflammation. Immune related functions regulated by SP-D include agglutination of pathogens, phagocytosis, oxidative burst, antigen presentation, T lymphocyte proliferation, cytokine secretion, induction of apoptosis and clearance of apoptotic cells. The present study unravels a novel ability of SP-D to reduce the viability of leukemic cells (eosinophilic leukemic cell line, AML14.3D10; acute myeloid leukemia cell line, THP-1; acute lymphoid leukemia cell lines, Jurkat, Raji; and human breast epithelial cell line, MCF-7), and explains the underlying mechanisms. SP-D and a recombinant fragment of human SP-D (rhSP-D) induced G2/M phase cell cycle arrest, and dose and timedependent apoptosis in the AML14.3D10 eosinophilic leukemia cell line. Levels of various apoptotic markers viz. activated p53, cleaved caspase-9 and PARP, along with G2/M checkpoints (p21 and Tyr15 phosphorylation of cdc2) showed significant increase in these cells. We further attempted to elucidate the underlying mechanisms of rhSP-D induced apoptosis using proteomic analysis. This approach identified large scale molecular changes initiated by SPD in a human cell for the first time. Among others, the proteomics analysis highlighted a decreased expression of survival related proteins such as HMGA1, overexpression of proteins to protect the cells from oxidative burst, while a drastic decrease in mitochondrial antioxidant defense system. rhSP-D mediated enhanced oxidative burst in AML14.3D10 cells was confirmed, while antioxidant, N-acetyl-L-cysteine, abrogated the rhSP-D induced apoptosis. The rhSP-D mediated reduced viability was specific to the cancer cell lines and viability of human PBMCs from healthy controls was not affected. The study suggests involvement of SP-D in hostā€™s immunosurveillance and therapeutic potential of rhSP-D in the eosinophilic leukemia and cancers of other origins.Department of Biotechnology, Indi
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