28 research outputs found
Les conduites parentales comme mĂ©canisme du lien entre le tempĂ©rament et les comportements extĂ©riorisĂ©s chez les enfants d'Ăąge scolaire : un modĂšle influencĂ© par la relation entre lâenfant et la personne enseignante
Les troubles du comportement extĂ©riorisĂ©s (TCE) se caractĂ©risent principalement par des comportements dâagressivitĂ©, dâimpulsivitĂ© ou dâopposition. Le modĂšle thĂ©orique de Granic et Patterson (2006) illustre, de maniĂšre intĂ©grĂ©e, diffĂ©rents facteurs impliquĂ©s dans la trajectoire dĂ©veloppementale des jeunes qui prĂ©sentent des TCE entre lâenfance et lâĂąge adulte. SpĂ©cifiquement, les difficultĂ©s tempĂ©ramentales de lâenfant (p. ex. faible affectivitĂ© nĂ©gative, extraversion Ă©levĂ©e ou faible rĂ©gulation volontaire) le mettraient plus Ă risque dâĂȘtre confrontĂ© Ă des conduites parentales inappropriĂ©es (p. ex. hostilitĂ©, permissivitĂ©) en rĂ©ponse Ă ses comportements. Un patron dâinteraction parent-enfant problĂ©matique pourrait alors sâinstaller au sein de la dyade. Avec le temps, les enfants exposĂ©s Ă des conduites parentales hostiles et/ou permissives en viennent Ă dĂ©velopper des comportements extĂ©riorisĂ©s plus manifestes tels que de lâagressivitĂ© et de lâopposition. Le modĂšle de Granic et Patterson (2006) suggĂšre Ă©galement que les enfants exposĂ©s Ă de telles conduites de la part de leurs parents tendent Ă gĂ©nĂ©raliser leurs comportements avec leurs pairs. Or, bien que moins mises de lâavant dans le modĂšle, dâautres personnes significatives peuvent aussi exercer une influence dans la vie des enfants qui prĂ©sentent des TCE, notamment la personne enseignante. Certaines Ă©tudes rĂ©centes ont dâailleurs montrĂ© quâune relation plus nĂ©gative avec la personne enseignante peut accentuer lâinfluence de conduites parentales plus adverses sur le dĂ©veloppement des TCE, alors quâune relation entre lâenfant et la personne enseignante (REE) plus positive pourrait en amoindrir lâinfluence (Roubinov et al., 2020; Wang et al., 2021). De mĂȘme, le modĂšle nâaborde pas lâimpact des conduites parentales plus positives, comme la sensibilitĂ© parentale, sur la trajectoire des jeunes qui prĂ©sentent des TCE. Lâobjectif du prĂ©sent mĂ©moire est donc dâexaminer le rĂŽle mĂ©diateur des conduites parentales dâhostilitĂ©, de permissivitĂ© et de sensibilitĂ© dans la relation entre le tempĂ©rament et les TCE chez les enfants dâĂąge scolaire, en plus de considĂ©rer le rĂŽle modĂ©rateur de la REE dans lâassociation entre les conduites parentales et les TCE.
Ce mĂ©moire repose sur des donnĂ©es longitudinales issues dâun projet plus large intitulĂ© lâĂtude longitudinale sur les troubles du comportement des filles et des garçons (DĂ©ry et al., 2007-2021; Lapalme et al., 2018-2023). LâĂ©chantillon de la prĂ©sente Ă©tude est composĂ© de 434 enfants (44,70 % de filles) prĂ©sentant des comportements extĂ©riorisĂ©s sĂ©vĂšres au T1 (M Ăąge de l'enfant = 8,40; ET = 0,94). Les parents ont rĂ©pondu Ă des questionnaires portant sur le tempĂ©rament de leur enfant au T1 et leurs conduites parentales au T3 (M Ăąge de l'enfant = 10,29 ; ET = 0,95). Les personnes enseignantes ont Ă©galement Ă©valuĂ© la qualitĂ© de leur relation avec l'enfant au T3. Enfin, les parents ont rĂ©pondu Ă des questionnaires permettant dâĂ©valuer les TCE de leur enfant au T1 et au T4 (M Ăąge de l'enfant = 11,29 ; ET = 0,94).
Pour rĂ©pondre aux objectifs du prĂ©sent mĂ©moire, une analyse acheminatoire par modĂšles dâĂ©quations structurelles (SEM) a Ă©tĂ© rĂ©alisĂ©e permettant de tester les diffĂ©rents liens de mĂ©diations modĂ©rĂ©es simultanĂ©ment. Ă partir de cette analyse, trois modĂšles indirects modĂ©rĂ©s se sont avĂ©rĂ©s significatifs en contrĂŽlant pour le niveau initial (T1) de TCE des enfants. Ces modĂšles ont rĂ©vĂ©lĂ© qu'une plus grande hostilitĂ© parentale explique en partie l'association entre une plus faible rĂ©gulation volontaire chez l'enfant et des TCE plus sĂ©vĂšres au dĂ©but de l'adolescence, ainsi que l'association entre une plus grande affectivitĂ© nĂ©gative chez l'enfant et des TCE plus sĂ©vĂšres au dĂ©but de l'adolescence, mais seulement lorsque la personne enseignante rapporte une proximitĂ© faible Ă modĂ©rĂ©e avec l'enfant. Une plus grande permissivitĂ© parentale explique en partie l'association entre une faible rĂ©gulation volontaire chez l'enfant et des TCE plus Ă©levĂ©s au dĂ©but de l'adolescence, mais uniquement lorsque la personne enseignante rapporte une proximitĂ© Ă©levĂ©e avec l'enfant. Ces rĂ©sultats appuient le modĂšle de Granic et Patterson (2006) et soulignent que les vulnĂ©rabilitĂ©s tempĂ©ramentales de lâenfant sont associĂ©es Ă des conduites parentales plus adverses, qui contribuent Ă leur tour au dĂ©veloppement de comportements extĂ©riorisĂ©s plus sĂ©vĂšres chez les enfants. Les rĂ©sultats permettent Ă©galement de contribuer au modĂšle en montrant que la proximitĂ© avec la personne enseignante peut agir comme facteur de protection pour les enfants exposĂ©s Ă des conduites parentales plus hostiles. Cela suggĂšre que les personnes enseignantes qui sont en mesure dâoffrir aux enfants qui prĂ©sentent des TCE une expĂ©rience relationnelle diffĂ©rente et plus positive pourrait leur permettre de rĂ©viser leurs schĂšmes relationnels et de diminuer leurs TCE. Or, les rĂ©sultats suggĂšrent aussi que la proximitĂ© dans la REE pourrait agir comme facteur de risque pour les enfants exposĂ©s Ă des conduites parentales plus permissives. Bien que surprenant, ce rĂ©sultat pourrait suggĂ©rer quâun Ă©quilibre entre la proximitĂ© et la mise en place de limites dans la REE serait plus bĂ©nĂ©fique pour les enfants exposĂ©s Ă des conduites parentales plus permissives. Quelques recommandations cliniques sont formulĂ©es Ă la lumiĂšre de ces constats. Dâabord, les rĂ©sultats soulignent lâimportance de soutenir les personnes enseignantes dans le dĂ©veloppement dâune relation qui permet de rĂ©pondre aux besoins spĂ©cifiques des enfants en considĂ©rant leur tempĂ©rament et les conduites parentales auxquelles ils ont Ă©tĂ© exposĂ©s. Des actions concertĂ©es entre les diffĂ©rents acteurs significatifs dans la vie des enfants (parents et personnes enseignantes) seraient aussi des plus pertinentes pour les mener sur une trajectoire dĂ©veloppementale plus adaptĂ©e
Temperament and externalizing problems
Abstract : This study examines how maternal adverse parenting (hostility, neglect, low warmth) and psychological distress explain the associations between child temperament factors and externalizing problems. It also examines if these associations differ according to the childâs biological sex. The sample consists of 339 school-age children receiving in-school services for conduct problems. Data were collected through questionnaires completed by mothers at 3 time points, at one-year intervals. Results from path analyses revealed that maternal psychological distress partly explained the associations between each child temperamental factors (negative affectivity, surgency/extraversion, effortful control) and levels of externalizing problems. Specifically, the indirect effect of psychological distress on child negative affectivity and externalizing problems was only significant for boys, not girls. Maternal hostility, on the other hand, mediated the association between child surgency/extraversion and externalizing problems in both boys and girls. Interestingly, neglectful parenting and maternal warmth did not explain the association between child temperamental factors and externalizing problems. The findings suggest small but significant temperament child-driven effects on maternal psychological distress and hostility, in turn, translating into higher levels of externalizing problems. These findings support the relevance of temperament-based interventions for children with conduct problems and of increased mental health support for their mothers. By aiding mothers in developing a larger repertoire of parenting strategies, mothers may be better equipped to respond appropriately to their child with various temperamental characteristics, hence, reducing their psychological distress and hostile behaviors and limiting the development of externalizing problems
Determinants of urinary concentrations of dialkyl phosphates among pregnant women in Canada â Results from the MIREC study
AbstractOrganophosphate (OP) insecticides are commonly used in agriculture. Their use decreased in recent years as they were gradually replaced by other pesticides, but some OPs are still among the insecticides most used in Canada. Exposure to elevated levels of OPs during pregnancy has been associated with adverse birth outcomes and poorer neurodevelopment in children. The objective of the present study was to examine the relationship between the concentrations of OP pesticides urinary dialkyl phosphate (DAP) metabolites and various factors that are potential sources of exposure or determinants of DAP levels. In the Maternal-Infant Research on Environmental Chemicals (MIREC) Study, six DAPs were measured in 1st trimester urine samples of 1884 pregnant women living in Canada. They were grouped into sums of dimethyl alkyl phosphates (DMAP) and diethyl alkyl phosphates (DEAP) for statistical analysis. We found that 93% of women had at least one DAP detected in their urine. Geometric means (GM) of specific gravity-corrected levels for urine dilution were 59 (95% CI 56â62) and 21 (95% CI 20â22) nmol/L for DMAP and DEAP, respectively. The following characteristics were significantly associated with higher urinary concentrations of DMAP or DEAP: higher education, nulliparous, normal pre-pregnancy body mass index, non-smoker, not fasting at sampling, winter season at sampling, and early and late day collection times. Dietary items that were significantly related with higher urinary concentrations included higher intake of citrus fruits, apple juice, sweet peppers, tomatoes, beans and dry peas, soy and rice beverages, whole grain bread, white wine and green and herbal teas. This study indicates that exposure to these compounds is quasi-ubiquitous. The factors associated with greater DAP levels identified here could be useful to regulatory agencies for risk analysis and management. However, some exposure misclassification might occur due to the single DAP measurement available, and to the presence of preformed DAPs in the environment
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Stitching Together the Urban Fabric
This Urban Design Studio in Springfield focused on incremental and systemic design changes at specific places in Downtown to improve the quality of life. The analysis investigated six interweaving, overlapping urban systems: Music and Art, Food and Retail, Working, Public Green, Education and Housing. Overlooked streets and their immediate context were of major focus: Worthington Street, Dwight Street, Willow Street and the stilted Interstate 91 viaduct.
Downtown Springfield is currently undergoing a substantial change of the physical urban fabric: The renovation of the Union Station into a multi-modal transportation hub, the MGM Casino Resort and the new Dr. Seuss Museum at the Quadrangle. While these projects create larger-scale hubs at the edges of downtown, there is the necessity of stitching Downtown together with small scale amenities and activities. How can we bridge the gaps and create stepping stones that make downtown streets a more walkable and bicycle-friendly experience? How can we create new economic opportunities and possibilities to serve needs for adult education, gathering and small-scale entertainment?
A Design Charrette with residents, stakeholders and community activists was held in the beginning of the studio. The charrette was organized around the six urban systems. The students led image-driven interviews with the community members, mapped places with existing assets or places with opportunities.
Four design scenarios were created: HEART OF THE CITY -DESIGNING ARTERIES FOR THE PEOPLE designed the urban fabric around Worthington Street. 24/7, year around programming of underutilized parking lots, public art and lighting, temporary closure of streets and activation of empty storefronts work together with a coherent design palette. DWIGHT STREET REVIVAL: Dwight Street is transformed into a green bike and walk artery with new and repurposed places for working, living, adult education, and art. STOCKBRIDGE SQUARE: A VILLAGE IN THE CITY creates a village in the city adjacent to the MGM Casino Resort with open space for the community, mixed use buildings, sustainable street systems, ground level retail and multiple market-rate housing options. The village will attract new residents in downtown. ECOLOGY VISION creates a healthy downtown Springfield with âtoolkitâ around restored urban ecological systems for a livable and beautiful city. A stormwater park underneath I-91 is accompanied by a pedestrian boulevard and an urban forest.
STITCHING TOGETHER THE URBAN FABRIC raises awareness for discovering the little notes and in-betweens. This proposal encompasses sustainability in a comprehensive way. It will make Springfield green and beautiful, will increase diversity, create jobs and bring vitality back
Reduced dielectric screening and enhanced energy transfer in single and few-layer MoS2
We report highly efficient non-radiative energy transfer from cadmium
selenide (CdSe) quantum dots to monolayer and few-layer molybdenum disulfide
(MoS2). The quenching of the donor quantum dot photoluminescence increases as
the MoS2 flake thickness decreases, with the highest efficiency (>95%) observed
for monolayer MoS2. This counterintuitive result arises from reduced dielectric
screening in thin layer semiconductors having unusually large permittivity and
a strong in-plane transition dipole moment, as found in MoS2. Excitonic energy
transfer between a 0D emitter and a 2D absorber is fundamentally interesting
and enables a wide range of applications including broadband optical
down-conversion, optical detection, photovoltaic sensitization, and color
shifting in light-emitting devices.Comment: 14 pages, 4 figure
Inhibition of Autoimmune Diabetes in NOD Mice by miRNA Therapy.
Autoimmune destruction of the pancreatic islets in Type 1 diabetes is mediated by both increased proinflammatory (Teff) and decreased regulatory (Treg) T lymphocytes resulting in a significant decrease in the Treg:Teff ratio. The non-obese diabetic (NOD) mouse is an excellent in vivo model for testing potential therapeutics for attenuating the decrease in the Treg:Teff ratio and inhibiting disease pathogenesis. Here we show for the first time that a bioreactor manufactured therapeutic consisting of a complex of miRNA species (denoted as TA1) can effectively reset the NOD immune system from a proinflammatory to a tolerogenic state thus preventing or delaying autoimmune diabetes. Treatment of NOD mice with TA1 resulted in a systemic broad-spectrum upregulation of tolerogenic T cell subsets with a parallel downregulation of Teff subsets yielding a dramatic increase in the Treg:Teff ratio. Moreover, the murine-derived TA1 was highly effective in the inhibition of allorecognition of HLA-disparate human PBMC. TA1 demonstrated dose-responsiveness and exhibited equivalent or better inhibition of allorecognition driven proliferation than etanercept (a soluble TNF receptor). These findings demonstrate that miRNA-based therapeutics can effectively attenuate or arrest autoimmune disease processes and may be of significant utility in a broad range of autoimmune diseases including Type 1 diabetes
The Science Performance of JWST as Characterized in Commissioning
This paper characterizes the actual science performance of the James Webb
Space Telescope (JWST), as determined from the six month commissioning period.
We summarize the performance of the spacecraft, telescope, science instruments,
and ground system, with an emphasis on differences from pre-launch
expectations. Commissioning has made clear that JWST is fully capable of
achieving the discoveries for which it was built. Moreover, almost across the
board, the science performance of JWST is better than expected; in most cases,
JWST will go deeper faster than expected. The telescope and instrument suite
have demonstrated the sensitivity, stability, image quality, and spectral range
that are necessary to transform our understanding of the cosmos through
observations spanning from near-earth asteroids to the most distant galaxies.Comment: 5th version as accepted to PASP; 31 pages, 18 figures;
https://iopscience.iop.org/article/10.1088/1538-3873/acb29
The James Webb Space Telescope Mission
Twenty-six years ago a small committee report, building on earlier studies,
expounded a compelling and poetic vision for the future of astronomy, calling
for an infrared-optimized space telescope with an aperture of at least .
With the support of their governments in the US, Europe, and Canada, 20,000
people realized that vision as the James Webb Space Telescope. A
generation of astronomers will celebrate their accomplishments for the life of
the mission, potentially as long as 20 years, and beyond. This report and the
scientific discoveries that follow are extended thank-you notes to the 20,000
team members. The telescope is working perfectly, with much better image
quality than expected. In this and accompanying papers, we give a brief
history, describe the observatory, outline its objectives and current observing
program, and discuss the inventions and people who made it possible. We cite
detailed reports on the design and the measured performance on orbit.Comment: Accepted by PASP for the special issue on The James Webb Space
Telescope Overview, 29 pages, 4 figure
Localization of cholecystokinin receptors in relation to the nigrostriatal and mesolimbic dopaminergic pathways
Additional file 1: of Concentrations of persistent organic pollutants in maternal and cord blood from the maternal-infant research on environmental chemicals (MIREC) cohort study
Results of Statistical Hypothesis TestingâMIREC Persistent Organic Pollutants Analysis-Using censoring methods. Table S1 Results for MIREC persistent organic pollutants in maternal blood by Parity (ÎŒg/L). Table S2 Results for MIREC persistent organic pollutants in maternal blood by maternal age (ÎŒg/L). Table S3 Results for MIREC persistent organic pollutants in maternal blood by smoking status (ÎŒg/L). Table S4 Results for MIREC persistent organic pollutants in maternal blood by household income (ÎŒg/L). Table S5 Results for MIREC persistent organic pollutants in maternal blood by pre-BMI (ÎŒg/L). Table S6 Results for MIREC persistent organic pollutants in maternal blood by place of birth (ÎŒg/L). Table S7 Results for MIREC persistent organic pollutants in maternal blood by fasting (ÎŒg/L). Table S8 Results for MIREC persistent organic pollutants in maternal blood by maternal education (ÎŒg/L). Table S9 Results for MIREC persistent organic pollutants in maternal blood by whether using non-stick cooking vessels. Table S10 Results for MIREC persistent organic pollutants in maternal blood by whether using non-stick cooking vessels in the microwave. Table S11 Results for MIREC persistent organic pollutants in maternal blood by year of collection. Table S12 Results for MIREC persistent organic pollutants in maternal blood by intake of bacon. Table S13 Results for MIREC persistent organic pollutants in maternal blood by intake of fish. Table S14 Results for MIREC persistent organic pollutants in maternal blood by intake of Hamburger. Table S15 Results for MIREC persistent organic pollutants in maternal blood by intake of pork. Table S16 Results for MIREC persistent organic pollutants in maternal blood by intake of poultry. Table S17 Results for MIREC persistent organic pollutants in maternal blood by intake of steak. Table S18 Comparison of demographic groups when the INTERACTION between BMI and total lipid was significant. Table S19 Comparison of demographic groups when the INTERACTION was significant between year of collection and total lipid. Table S20 Comparison of demographic groups when the INTERACTION was significant between intake of bacon and total lipid. Table S21 Results for MIREC persistent organic pollutants in cord blood by infant gender (ÎŒg/L). Table S22 Results for MIREC persistent organic pollutants in cord blood by season of collection (ÎŒg/L). Table S23 Results for MIREC persistent organic pollutants in cord blood by smoking status of mother (”g/L). (DOCX 207 kb