Highlights from the 24th conference on retroviruses and opportunistic infections, 13-16 February 2017, Seattle, Washington, USA

From the 13th to 16th February 2017, researchers from around the world convened for the 24th annual Conference on Retroviruses and Opportunistic Infections (CROI) at the Washington State Convention Center in Seattle, Washington. The conference was organised by the International Antiviral Society-USA (IAS-USA) in partnership with the CROI Foundation. The conference included over 1000 oral and poster presentations of peer-reviewed original research as well as lectures and symposia featuring insights from leading basic, translational and clinical researchers. Highlighted here are key data presented at the conference

Cirrhosis and liver transplantation in patients co-infected with HIV and hepatitis B or C:an observational cohort study

This study assessed the likelihood of referral for liver transplantation assessment in a prospective cohort of patients co-infected with HIV and hepatitis B or C with complications of cirrhosis. There were 141 co-infected patients from 11 UK centres with at least one complication of cirrhosis recorded (either decompensation or hepatocellular carcinoma) out of 772 identified with cirrhosis and/or HCC. Only 23 of these 141 (16.3%) were referred for liver transplantation assessment, even though referral is recommended for co-infected patients after the first decompensation episode

Neurocranium versus Face: A Morphometric Approach with Classical Anthropometric Variables for Characterizing Patterns of Cranial Integration in Extant Hominoids and Extinct Hominins

The relative importance of the two main cranial complexes, the neurocranium and the splanchnocranium, has been examined in the five species of extant hominoids and in a huge sample of extinct hominins using six standard craniometric variables that measure the length, width and height of each cranial module. Factor analysis and two-block partial least squares were used for establishing the major patterns of developmental and evolutionary integration between both cranial modules. The results obtained show that all extant hominoids (including the anatomically modern humans) share a conserved pattern of developmental integration, a result that agrees with previous studies. The pattern of evolutionary integration between both cranial modules in australopiths runs in parallel to developmental integration. In contrast, the pattern of evolutionary and developmental integration of the species of the genus Homo is the opposite, which is probably the consequence of distinctive selective regimes for both hominin groups.JAPC, JMJA and PP received fundings from Ministerio de Ciencia e Innovación, Gobierno de España (http://www.idi.mineco.gob.es), project CGL2011-30334, and Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía, España (http://www.juntadeandalucia.es/organismo​s/economiainnovacioncienciayempleo.html), project P11-HUM-7248 and Research Groups RNM-146 and HUM-607

Men battering as the new form of domestic violence? A pastoral care perspective from the Kenyan context

The article sets out to show that gender-based violence is no longer restricted to ‘women by men’. Rather society must appreciate that gender battering is a reality across the gender divide, particularly in the 21st century Africa. In its methodology, the article has engaged a theophilosophical approach that involves a social, religious, and a cultural analytical approach. The materials are gathered primarily after interviewing the staff and students from Kenyatta University, Mombasa Campus, and some selected people from the campus surroundings who were consulted orally. To this end, a questionnaire was released in June and July 2012 where about 200 respondents from across the various counties of Kenya were called upon to shedlight on men battering in Kenya. In particular, some of the questions that were posed included: Has battering of men by women been part of our African societies from ancient times or is it a new phenomenon? Statistically, who are battered more men or women? How does domestic violence against men manifest itself? What causes it? Why does it sound new to our society? What can we do about it? The article rests on the premise that even though battering of women is more explicit, men battering by women, which takes many forms, has been there for quite some time, albeit unreported. By taking a holistic approach hence ‘collective responsibility’ across the gender divide, the society can be healed from all forms of gender-based violence

Reconstructive hermeneutics in African Christology

The article sets out to demonstrate African reconstructive Christology as the seventh Christological trend in African Christianity. Considering that African theology is kerygmatically universal, but  theologically provincial, the study shows that Christology in our contemporary Africa can be best  understood by retracing it from the early Christological controversies through to the present times. Certainly, African Christology in the 21st century is dominated by calls for contextualisation,  indigenisation, rebirth, inculturation, renewal, rejuvenation, renaissance and reconstruction. To this end, the article endeavours to demonstrate that Christ, the ideal reconstructionist, the one who broke the cultural codes of his time in order to reconstruct the society, is the relevant model to our contemporary world. The article draws its theoretical framework from the works of Jesse Mugambi, Kä Mana, and Wachege, amongst other proponents of reconstructive motif in African theology. In its methodology, the article first attempts to identify some early Christological developments through to the  contemporary trends. It subsequently attempts a survey of the six Christological trends of the 20th century; that is a Christological trend that commits itself to interpreting and adapting Christology to modern mentality and situation; Christologies geared exclusively to the historical Jesus; Christology that tends to uphold the Trinitarian theology; Christologies based on the proclaimed Christ and the historical Jesus; Asian Christologies of inculturation and liberation; and African Christologies of inculturation and liberation. Afterwards, it analyses Christological trends of the 21st century where a seventh dimension, African reconstructive Christology, has become the norm. In so doing, the article builds on the premise that the primary task of African Christology today is restoration

The Menengai Tuff: a 36 ka widespread tephra and its chronological relevance to Late Pleistocene human evolution in East Africa

The East African Rift preserves the world's richest Middle and Late Pleistocene (∼780–12\ua0ka) geological, archaeological and paleontological archives relevant to the emergence of Homo sapiens. This region also provides unparalleled chronological control for many important sites through tephrochronology, the dating and correlation of volcanic ashes as widespread isochronous markers in the geological record. There are many well-characterized Pliocene-Early Pleistocene tephras that are widespread across East Africa. A comparable framework is lacking for the Middle and Late Pleistocene; a period characterized by spatially and temporally complex patterns of climate change, as well as the emergence of modern Homo sapiens and the dispersal of this species across and out of Africa. Unraveling relationships among these spatial and temporally complex phenomena requires a precise chronology. To this end we report the Menengai Tuff, a widespread volcanic ash produced by the large-scale caldera-forming eruption in Kenya and Ar/Ar dated to 35.62\ua0±\ua00.26\ua0ka. Geochemical characterization of 565 glass shards from 36 samples by wavelength-dispersive electron probe microanalysis show the Menengai Tuff was deposited over >115,000\ua0km and is found in the Baringo, Chalbi, Elmenteita, Nakuru, Olorgesailie, Turkana, and Victoria basins, all of which preserve rich Late Pleistocene paleoenvironmental and archaeological archives. Correlation and dating of the Menengai Tuff demonstrate that it is the most widespread tephra and largest eruption currently known from the Late Pleistocene of East Africa. As such, it is a valuable marker in establishing a Late Pleistocene chronology for paleoclimatic, archeological, and paleontological records relevant to the study of human evolution